An Analysis of Nectin-4 (PVRL4) in Penile Squamous Cell Carcinoma

European Urology Open Science - Tập 49 - Trang 1-5 - 2023
G.Daniel Grass1, Jad Chahoud2, Alex Lopez3, Jasreman Dhillon3, Steven A. Eschrich4, Peter A.S. Johnstone1, Philippe E. Spiess2
1Department of Radiation Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA
2Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA
3Department of Pathology, H Lee Moffitt Cancer Center, Tampa, FL, USA
4Department of Biostatistics and Bioinformatics Shared Resource, H. Lee Moffitt Cancer Center, Tampa, FL, USA

Tài liệu tham khảo

Thomas, 2021, Penile cancer, Nat Rev Dis Primers, 7, 11, 10.1038/s41572-021-00246-5 Joshi, 2022, Immune-based therapies in penile cancer, Nat Rev Urol, 19, 457, 10.1038/s41585-022-00617-x Joshi, 2022, Penile cancer: updates in systemic therapy, Asian J Urol, 9, 374, 10.1016/j.ajur.2022.03.006 Yan, 2022, First-line programmed death receptor-1 (PD-1) inhibitor and epidermal growth factor receptor (EGFR) blockade, combined with platinum-based chemotherapy, for stage IV penile cancer, BJU Int Liu, 2021, Role of Nectin-4 protein in cancer, Int J Oncol, 59, 93, 10.3892/ijo.2021.5273 Reches, 2020, Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity, J Immunother Cancer, 8, e000266, 10.1136/jitc-2019-000266 Heath, 2021, The biology and rationale of targeting nectin-4 in urothelial carcinoma, Nat Rev Urol, 18, 93, 10.1038/s41585-020-00394-5 Yuan, 2019, Intrinsic radiosensitivity, genomic-based radiation dose and patterns of failure of penile cancer in response to adjuvant radiation therapy, Rep Pract Oncol Radiother, 24, 593, 10.1016/j.rpor.2019.09.006 Kuasne, 2015, Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers, Clin Epigenet, 7, 46, 10.1186/s13148-015-0082-4 Azizi, 2019, Impact of PI3K-AKT-mTOR signaling pathway up-regulation on prognosis of penile squamous-cell carcinoma: results from a tissue microarray study and review of the literature, Clin Genitourin Cancer, 17, e80, 10.1016/j.clgc.2018.09.012