An ABO-blood group abnormality leading to the detection of a colon-carcinoma
Tóm tắt
A patient who had been admitted to hospital for surgical treatment of inguinal hernias was found to have a blood group phenotype of A1B in the presence of a non-auto-anti-B. No previous records of the patient's blood group were available. The serological workup including absorption and saliva inhibiton studies yielded a high probability for an acquired B-antigen which is known to be often associated with carcinoma of the colon. Subsequent coloscopy revealed the presence of a carcinoma of the sigmoid, unaccessable to palpation. To our knowledge this is the first report in the literature that the serological diagnosis of an acquired B-antigen led to the detection of a hitherto undetected carcinoma.
Tài liệu tham khảo
Byrne V, Brown A, Ropars C, Moore BPL (1979) Acquired B antigen, TK activation and A1 destroying enzyme activity in a patient with septicaemia. Vox Sang 36: 208
Garraty G, Willbanks E, Petz LD (1971) An acquired B antigen associated with proteus vulgaris infection. Vox Sang 21: 45
Lanset S, Ropartz C (1971) A second example of acquired B-like antigen in a healthy person. Vox Sang 20: 82
Marsh WL (1960) The pseudo-B antigen. A study of its development. Vox Sang 5: 387
Marsh WL (1970) Letter to the editor. Transfusion 10: 41
Race RR, Sanger R (1968) Bloodgroups in man, 5th edn. Blackwell, Oxford Edinburgh, p 29
Rekvig OP, Hannestad K (1977) Acid elution of blood group antibodies from intact erythrocytes. Vox Sang 33: 280
Springer GF (1966) Beziehungen zwischen Mikroben und blutgruppenaktiven Substanzen. Angew Chem 78: 967
Stratton F, Renton PH (1959) Acquisition of B-like antigen. Br Med J 2: 244