Amberlyst-15, an efficient heterogeneous catalyst for the 1,4-dihydropyridine synthesis

Vietnam Journal of Catalysis and Adsorption - Tập 11 Số 4 - Trang 86-91 - 2022
Tran Quang Hung1, Pham Thi Thanh Loan2, Do Thi Lan Nhi2, Ban Van Phuc1, Nguyen Hien2, Dang Thanh Tuan3, Duong Ngoc Tu1, Do Van Dang3, Vu Xuan Hoan4
1Institute of Chemistry, Vietnam Academy of Science and Technology
2Faculty of Chemistry, Hanoi National University of Education
3Faculty of Chemistry, Hanoi University of Science, Vietnam National University
4Vietnam Petroleum Institute

Tóm tắt

The paper reported synthesizing 1,4-dihydropyridine (1,4-DHP) from β-ketoester, aromatic aldehyde, and ammonium acetate via a two-step, using heterogeneous catalyst Amberlyst-15 in high yields at room temperature. The method was applied to synthesize some 1,4-DHP derivatives. Moreover, the catalyst was reused at least five times without loss of catalytic activity under eco-friendly conditions.

Từ khóa

#1 #4-dihydropyridine #amberlyst-15 #heterogeneous catalyst

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