Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Nature - Tập 373 Số 6514 - Trang 523-527 - 1995
Dora Games1, David S. Adams2, Ree Alessandrini3, Robin Barbour1, Patricia Borthelette4, Catherine Blackwell5, Tony Carr1, James A. Clemens6, Thomas Donaldson3, Frances P. Gillespie3, Terry Guido1, S. Hagopian7, Kelly Johnson‐Wood1, Karen Khan1, Mike Lee1, Paul J. Leibowitz3, Ivan Lieberburg1, Sheila P. Little6, Eliezer Masliah8, Lisa McConlogue1, Martin Montoya‐Zavala3, Lennart Mucke9, Lisa Paganini1, Elizabeth Penniman3, Mike Power1, Dale Schenk1, Peter Seubert1, Ben Snyder3, Ferdie Soriano1, Hua Tan1, James Vitale10, Sam Wadsworth3, Ben Wolozin11, Jun Zhao1
1Athena Neurosciences Inc., South San Francisco, USA
2Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, USA
3Exemplar Corporation, Worcester, USA
4Genzyme Corporation, Framingham, USA
5Department of Veterin-arian and Animal Sciences, University of Massachusetts, Amherst, USA
6Lilly Research Laboratories, Indianapolis, USA
7Joint Program in Neonatology, Children's Hospital, Enders, Rm 950, Boston, USA
8Department of Neurosciences, University of California—San Diego, La Jolla, USA
9Department of Neuropharmacology, The Scripps Research Institute, La Jolla USA
10Millennium Pharmaceuticals Inc., Cam-bridge, USA
11Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, USA

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Tài liệu tham khảo

Selkoe, D. J. A. Rev. Neurosci. 17, 489–517 (1994).

Hardy, J. Clin. geriatr. Med. 10, 239–247 (1994).

Mann, D. M. A. et al. Neurodegeneration 1, 201–215 (1992).

Quon, D. et al. Nature 352, 239–241 (1991).

Sanhu, F. A., Salim, M. & Zain, S. B. J. biol. Chem. 266, 21331–21334 (1991).

Lamb, B. T. et al. Nature Genet. 5, 22–30 (1993).

Pearson, B. E. & Choi, T. K. Proc. natn. acad. Sci. U.S.A. 90, 10578–10582 (1993).

Mucke, L. et al. Brain Res. 666, 151–167 (1994).

McConlogue, L. et al. Neurobiol. Aging 15, S12 (1994).

Higgins, L. S. et al. Ann. Neurol. 35, 598–607 (1994).

Sasahara, M. et al. Cell 64, 217–227 (1991).

Murrell, J. et al. Science 254, 97–99 (1991).

Seubert, P. et al. Nature 359, 325–327 (1992).

Cork, L. C. et al. J. Neuropath. exp. Neurol. 47, 629–641 (1988).

Masliah, E. et al. Am. J. Path. 138, 235–246 (1991).

Suzuki, N. et al. Science 264, 1336–1340 (1994).

Roher, A. et al. J. biol. Chem. 269, 3072–3083 (1993).

Maggio, J. E. et al. Proc. natn Acad. Sci. U.S.A. 89, 5462–5466 (1992).

Hogan, B., Constantini, F. & Lacey, E. in Manipulating the Mouse Embryo: A Laboratory Manual (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986).

Chomazynski, P. & Sacchi, N. Analyt. Biochem. 162, 156–159 (1987).

Wang, A. M. et al. Proc. natn. Acad. Sci. U.S.A. 86, 9717–9721 (1989).

Oltersdorf, T. et al. J. biol. Chem. 265, 4492–4497 (1990).

Arai, H. et al. Proc. natn. Acad. Sci. U.S.A. 87, 2249–2253 (1990).

Tamaoka, A. et al. Proc. natn. Acad. Sci. U.S.A. 89, 1345–1349 (1992).

Games, D. et al. Neurobiol. Aging 13, 569–576 (1992).

Saido, T. C. et al. J. biol. Chem. 269, 15253–15257 (1994).

Dickson, D. W. et al. Acta neuropath. 79, 486–493 (1990).

Masliah, E. et al. J. Neuropath. exp. Neurol. 52, 619–632 (1993).

Masliah, E. et al. Acts neuropath. 81, 428–433 (1991).

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Nature

Tập 373 Số 6514

523-527

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