Alteration of Adenosine Receptors in Patients with Chronic Obstructive Pulmonary Disease

10.1183/09031936.02.01132002

Fredholm BB, Ijzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001;53:527–552.

10.1124/pr.56.4.2

10.1358/dnp.2003.16.5.829316

10.1006/pupt.1999.0191

Varani K, Merighi S, Gessi S, Klotz KN, Leung E, Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Borea PA. [3H]-MRE 3008–F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. Mol Pharmacol 2000;57:968–975.

10.1096/fj.02-0543fje

10.1124/mol.67.1.

10.1124/mol.61.2.415

10.1158/1078-0432.CCR-1134-03

10.1056/NEJMoa032158

Morello S, Ito K, Barnes PJ, Adcock IM. Regulation of adenosine A2A receptor expression in human epithelial cells by inflammatory cytokines. Am J Respir Crit Care Med 2004;169:A196.

Varani K, Caramori G, Casolari P, Pancaldi C, Vincenzi F, Adcock IM, Chung KF, Barnes PJ, Cavallesco G, Azzena G, Borea PA, Papi A. Expression of adenosine receptors in the peripheral lung from COPD patients [abstract]. Proc Am Thorac Soc 2005;2:A399.

10.1164/ajrccm.162.5.9910112

10.1183/09041950.005s1693

10.1136/thorax.58.4.348

10.1038/nbt0993-1026

10.1016/0003-2697(80)90515-1

Ito K, Ito M, Elliot WM, Cosio B, Caramori G, Min Kon O, Barczyk A, Hayashi S, Adcock IM, Hogg JC, et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005; 12:1967–1976.

10.1016/j.healun.2004.06.016

10.1002/(SICI)1098-2299(199811/12)45:3/4<198::AID-DDR17>3.0.CO;2-#

10.1172/JCI118245

Rorke S, Holgate ST. Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. Am J Respir Med 2002;2:99–105.

Ezeamuzie CI, Philips E. Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release. Br J Pharmacol 2001;62:1163–1173.

10.1172/JCI22656

Sullivan GW. Adenosine A2A receptor agonists as anti-inflammatory agents. Curr Opin Investig Drugs 2003;4:1313–1319.

10.2174/1568026043450989