Alpha interferon: The potential drug of adjuvant therapy: Past achievements and future challenges

Davis, 1989, Treatment of chronic hepatitis C with recombinant interferon alfa, N Engl J Med, 321, 1501, 10.1056/NEJM198911303212203 Berman, 1989, Synergistic cytotoxic effect of azidothymidine and recombinant interferon alpha and normal bone marrow progenitor cells, Blood, 74, 1281, 10.1182/blood.V74.4.1281.1281 Reprecht, 1990, Interferon alfa and 3′ azido-deoxythymidine are highly synergistic in mice and prevent viremia after acute retrovirus exposure, J Acquired Immune Def Syndromes, 3, 591 deWit, 1988, Clinical and virological effects of high dose recombinant interferon alpha in disseminated AIDS related Kaposi's sarcoma, Lancet, ii, 1214, 10.1016/S0140-6736(88)90810-0 Lane, 1990, Interferon-α in patients with asymptomatic human immunodeficiency infection, Ann Intern Med, 112, 805, 10.7326/0003-4819-112-11-805 Schneider, 1987, Interferon treatment of human genital papillomavirus infection: Importance of viral type, Int J Cancer, 40, 610, 10.1002/ijc.2910400506 Reid, 1990, Use of interferon and laser therapy vs laser or laser and 5FU in treatment of vaginal intraepithelial neoplasia, Am Soc Colposcopy Ikic, 1981, Application of human leukocyte interferon in patients with carcinoma of the uterine cervix, Lancet, i, 1027, 10.1016/S0140-6736(81)92190-5 Seto, 1983, Local IFN treatment of intraepithelial neoplasia, Antiviral Res, 2, 34 Hsu, 1984, Exfoliative cytology in the evaluation of interferon treatment of cervical intraepithelial neoplasia, Acta Cytol, 28, 111 Einat, 1985, Close link between reduction of c-myc expression by interferon and G0G1 arrest, Nature, 313, 597, 10.1038/313597a0 Piacibello, 1986, Human gamma interferon modifies c-myc expression and growth pattern of U-937 but not its subclone 1937, Cell Biol Intl, 10, 467, 10.1016/0309-1651(86)90042-1 Kelley, 1985, Differential regulation of interferon induced mRNAs and c-myc mRNA by α and γ interferon, Eur J Biochem, 153, 367, 10.1111/j.1432-1033.1985.tb09312.x Yarden, 1986, Tumor necrosis factor reduces c-myc expression and cooperates with interferon γ in Hela cells, Science, 234, 1419, 10.1126/science.3097823 Elias, 1980, Altered pattern of differentiation and proliferation of HL-60 promyelocytic leukemia cells in presence of leucocyte conditioned medium, Leukaemia Res, 4, 301, 10.1016/0145-2126(80)90037-5 Ball, 1984, Gamma interferon induces monocytoid differentiation in the HL-60 cell line, J Clin Invest, 73, 1072, 10.1172/JCI111292 Takei, 1984, The role of interferon γ in induction of differentiation of human myeloid leukemia cell lines, ML-1 and HL-60, Biochem Biophys Res Commun, 100, 10.1016/0006-291X(84)90922-7 Ralph, 1983, Lymphokine induced terminal differentiation of the human monoblast leukemia line U937: A role of gamma interferon, Blood, 62, 1169, 10.1182/blood.V62.6.1169.1169 Gisslinger, 1990, Long-term alfa interferon therapy in myelodysplastic syndromes, Leukemia, 4, 91 Data on file. Schering-Plough Research, Kenilworth, NJ, USA. Berek, 1985, Intraperitoneal recombinant alfa interferon for salvage immunotherapy in stage III epithelial ovarian cancer, Cancer Res, 45, 4447 Talpaz, 1987, Clinical investigation of human alfa interferon in chronic myelogenous leukemia, Blood, 69, 1280, 10.1182/blood.V69.5.1280.1280 Golomb, 1986, Alpha-2-interferon therapy of hairy cell leukemia: A multicenter study of 64 patients, J Clin Oncol, 4, 900, 10.1200/JCO.1986.4.6.900 Maluish, 1985, Phase II trial of recombinant leukocyte interferon for advanced hairy cell leukemia, 4, 221 Cooper, 1987, Interferons in the treatment of myeloma, Cancer, 59, 594, 10.1002/1097-0142(19870201)59:3+<594::AID-CNCR2820591303>3.0.CO;2-7 Costanzi, 1985, Phase II study of alfa-2b interferon in resistant multiple myeloma, J Clin Oncol, 3, 654, 10.1200/JCO.1985.3.5.654 Gutterman, 1980, Leukocyte interferon induced tumor regression in human metastatic breast cancer, multiple myeloma and malignant lymphoma, Ann Intern Med, 93, 399, 10.7326/0003-4819-93-3-399 Quesada, 1986, Treatment of multiple myeloma with recombinant alfa interferon, Blood, 67, 275, 10.1182/blood.V67.2.275.275 Niederle, 1990, Efficacy of alpha IFN and alpha IFN plus gamma in chronic myelogenous leukemia, Blood, 61, 191 Kantarjian, 1990, Treatment of advanced stages of Philadelphia chromosome positive chronic myelogenous leukemia with alpha interferon and low dose cytosine arabinoside, Exp Hematol, 18, 8 Talpaz, 1990, Sustained complete cytogenetic responses among Philadelphia positive chronic myelogenous leukemia patients treated with alpha interferon, Exp Hematol, 18, 6 Medenica, 1989, Interferon pulse therapy vs. continuous therapy of chronic myelogenous leukemia, Blood, 74, 364 Horning, 1985, Human interferon alpha in malignant lymphoma and Hodgkin's disease, Cancer, 56, 1305, 10.1002/1097-0142(19850915)56:6<1305::AID-CNCR2820560614>3.0.CO;2-N Sherwin, 1983, Phase II efficacy of recombinant leukocyte interferon in previously treated non-Hodgkin's lymphoma, 2, 211 Foon, 1984, Treatment of advanced non-Hodgkin's lymphoma with recombinant leukocyte interferon, N Engl J Med, 311, 1148, 10.1056/NEJM198411013111803 Evans, 1991, Interferon alpha-2a in the treatment of acquired immunodeficiency syndrome related Kaposi's sarcoma, J Immunother, 10, 39, 10.1097/00002371-199102000-00006 Krown, 1983, Preliminary observations on the effect of recombinant leukocyte interferon in homosexual men with Kaposi's sarcoma, N Engl J Med, 18, 1071, 10.1056/NEJM198305053081806 Quesada, 1985, Phase II study of alpha interferon in metastatic renal cell carcinoma, J Clin Oncol, 3, 1086, 10.1200/JCO.1985.3.8.1086 Muss, 1987, Recombinant alfa interferon in renal cell carcinoma, J Clin Oncol, 5, 286, 10.1200/JCO.1987.5.2.286 Mattson, 1989, Low dose natural alfa interferon as maintenance for small cell lung cancer, 8, 227 Meyers, 1987, Prophylactic use of human leukocyte interferon after allogeneic marrow transplantation, Ann Intern Med, 107, 809, 10.7326/0003-4819-107-6-809 Mandelli, 1990, Maintenance treatment with recombinant alfa-2b interferon in patients with multiple myeloma responding to conventional induction chemotherapy, N Engl J Med, 322, 1430, 10.1056/NEJM199005173222005 Lister, 1991, Interferon alfa-2b in addition to chlorambucil in the treatment of follicular lymphoma: Preliminary results of a randomized trial in progress, Eur J Cancer Moshowitz, 1982, Xenograft model of alfa IFN in combination with cisplatinum in P388 leukemia, J Infect Res, 2, 887 Balkwill, 1984, Xenograft model of interactions between alfa interferon and xenograft model of breast carcinoma, Cancer Res, 44, 904 Chang, 1983, Inhibition of cell growth in synchronous human hypernephroma cells by recombinant interferon alfa D and irradiation, J Interferon Res, 3, 379, 10.1089/jir.1983.3.379 Bonnem, 1987, Alfa interferon: Combination with other antineoplastic modalities, Semin Oncol, 2, 48 Wadler, 1990, Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies, 50, 3473 Clark, 1987, Two randomized trials of intermittent intravenous versus subcutaneous alpha 2 interferon alone or in combination with 5 fluorouracil in advanced colorectal carcinoma, Int J Colorectal Dis, 2, 26, 10.1007/BF01648994 Kreuser, 1989, Phase I–II study with recombinant alfa-2b-interferon, folinic acid and 5-fluorouracil in metastasized intestinal cancer, Oncology, 12, 20 Wadler, 1989, Fluorouracil and recombinant alfa-2a interferon: An active regimen against advanced colorectal carcinoma, J Clin Oncol, 7, 1769, 10.1200/JCO.1989.7.12.1769 Kemeny, 1990, Combination 5-fluorouracil and recombinant alfa interferon in advanced colorectal carcinoma, 9, 117 Huberman, 1990, 5-fluorouracil plus recombinant alfa interferon in advanced colorectal cancer, 9, 116 Pazdur, 1990, Phase II study of recombinant interferon and 5-fluorouracil in patients with advanced colorectal carcinoma, 9, 117