All four zebrafish Wnt7 genes are expressed during early brain development

Amores, 1998, Zebrafish hox clusters and vertebrate genome evolution, Science, 282, 1711, 10.1126/science.282.5394.1711 Carl, 2007, Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries, Neuron, 55, 393, 10.1016/j.neuron.2007.07.007 Carta, 2004, Wnt7a is a suppressor of cell death in the female reproductive tract and is required for postnatal and estrogen-mediated growth, Biology of Reproduction, 71, 444, 10.1095/biolreprod.103.026534 Chiu, 2010, Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation, Developmental Biology, 344, 1071, 10.1016/j.ydbio.2010.05.495 Dealy, 1993, Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes, Mechanisms of Development, 43, 175, 10.1016/0925-4773(93)90034-U Drummond, A.J., Ashton, B., Buxton, S., Cheung, M., Cooper, A., Heled, J., Kearse, M., Moir, R., Stones-Havas, S., Sturrock, S., Thierer, T., Wilson, A., 2010. Geneious v5.1, Available from:http://www.geneious.com. Essner, 2005, Kupffer’s vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut, Development, 132, 1247, 10.1242/dev.01663 Garriock, 2007, Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16, Developmental Dynamics, 236, 1249, 10.1002/dvdy.21156 Guindon, 2003, A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood, Systematic Biology, 52, 696, 10.1080/10635150390235520 Hall, 2000, Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling, Cell, 100, 525, 10.1016/S0092-8674(00)80689-3 Hollyday, 1995, Wnt expression patterns in chick embryo nervous system, Mechanisms of Development, 52, 9, 10.1016/0925-4773(95)00385-E Huelsenbeck, 2001, MRBAYES: bayesian inference of phylogenetic tress, Bioinformatics, 17, 754, 10.1093/bioinformatics/17.8.754 Kengaku, 1998, Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud, Science, 280, 1274, 10.1126/science.280.5367.1274 Kudoh, T., Concha, M.L., Houart, C., Dawid, I.B. and Wilson, S.W., 2004. Combinatorial FGF and BMP signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. Development in press. Li, 2001, Decreased expression of Wnt7a mRNA is inversely associated with the expression of estrogen receptor-α in human uterine leiomyoma, Journal of Clinical Endocrinology & Metabolism, 86, 454, 10.1210/jc.86.1.454 Macdonald, 1994, Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain, Neuron, 13, 1039, 10.1016/0896-6273(94)90044-2 Miller, 1998, Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract, Development, 125, 3201, 10.1242/dev.125.16.3201 Norton, 2005, HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development, Development, 132, 4963, 10.1242/dev.02084 Nusse, 1982, Many tumors induced by mouse mammary tumor virus contain a provirus integrated in the same region of the host chromosome, Cell, 31, 99, 10.1016/0092-8674(82)90409-3 Nüsslein-Vollhardt, 1980, Mutations affecting segment number and polarity in Drosophila, Nature, 287, 795, 10.1038/287795a0 Parr, 2001, Wnt7b regulates placental development in mice, Developmental Biology, 237, 324, 10.1006/dbio.2001.0373 Parr, 1995, Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb, Nature, 374, 350, 10.1038/374350a0 Parr, 1998, Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a, Nature, 395, 707, 10.1038/27221 Parr, 1993, Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds, Development, 119, 247, 10.1242/dev.119.1.247 Postlethwait, 2000, Zebrafish comparative genomics and the origins of vertebrate chromosomes, Genome Research, 10, 1890, 10.1101/gr.164800 Postlethwait, 1998, Vertebrate genome evolution and the zebrafish gene map, Nature Genetics, 18, 345, 10.1038/ng0498-345 Rajagopal, 2008, Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme, Development, 135, 1625, 10.1242/dev.015495 Rieger, 2010, The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers, Molecular and Cellular Biology, 30, 4267, 10.1128/MCB.01418-09 Rijsewijk, 1987, The Drosophila homologue of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless, Cell, 50, 649, 10.1016/0092-8674(87)90038-9 Rosso, 2005, Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development, Nature Neuroscience, 8, 34, 10.1038/nn1374 Sahores, 2010, Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis, Development, 137, 2215, 10.1242/dev.046722 Semenov, 2007, SnapShot: noncanonical Wnt signaling pathways, Cell, 131, 1378, 10.1016/j.cell.2007.12.011 Shu, 2002, Wnt7b regulates mesenchymal proliferation and vascular development in the lung, Development, 129, 4831, 10.1242/dev.129.20.4831 Sidow, 1992, Diversification of the Wnt gene family on the ancestral lineage of vertebrates, PNAS, 89, 5098, 10.1073/pnas.89.11.5098 Stenman, 2008, Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature, Science, 322, 1247, 10.1126/science.1164594 Tu, 2007, Noncanonical Wnt signaling through G protein-linked PKCd activation promotes bone formation, Developmental Cell, 12, 113, 10.1016/j.devcel.2006.11.003 van Amerongen, 2009, Towards an integrated view of Wnt signaling in development, Development, 136, 3205, 10.1242/dev.033910 Viktorin, 2009, Emx3 is required for the differentiation of dorsal telencephalic neurons, Developmental Dynamics, 238, 1984, 10.1002/dvdy.22031 Wang, 2005, Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5, Molecular and Cellular Biology, 25, 5022, 10.1128/MCB.25.12.5022-5030.2005 Westerfield, 1995 Wittbrodt, 2002, Medaka – a model organism from the far East, Nat Rev Genet, 3, 53, 10.1038/nrg704 Woods, 2006, Mutations in WNT7A cause a range of limb malformations, including fuhrmann syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome, The American Journal of Human Genetics, 79, 402, 10.1086/506332 Yu, 2009, A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney, Development, 136, 161, 10.1242/dev.022087