Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

Wong, 2013, Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations?, Antimicrob Agents Chemother, 57, 6165, 10.1128/AAC.00951-13 Ulldemolins, 2011, The effects of hypoalbuminaemia on optimizing antibiotic dosing in critically ill patients, Clin Pharmacokinet, 50, 99, 10.2165/11539220-000000000-00000 Mimoz, 2006, Steady-state trough serum and epithelial lining fluid concentrations of teicoplanin 12mg/kg per day in patients with ventilator-associated pneumonia, Intensive Care Med, 32, 775, 10.1007/s00134-006-0136-3 Lamont, 2009, Development of teicoplanin dosage guidelines for patients treated within an outpatient parenteral antibiotic therapy (OPAT) programme, J Antimicrob Chemother, 64, 181, 10.1093/jac/dkp147 Soy, 2006, Teicoplanin population pharmacokinetic analysis in hospitalized patients, Ther Drug Monit, 28, 737, 10.1097/01.ftd.0000249942.14145.ff Roberts, 2014, Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: lessons from the DALI Study, Int J Antimicrob Agents, 43, 423, 10.1016/j.ijantimicag.2014.01.023 Brink, 2008, Recommendations to achieve rapid therapeutic teicoplanin plasma concentrations in adult hospitalised patients treated for sepsis, Int J Antimicrob Agents, 32, 455, 10.1016/j.ijantimicag.2008.05.012 Greenberg, 1990, Treatment of bone, joint and vascular-access-associated Gram-positive bacterial infections with teicoplanin, Antimicrob Agents Chemother, 34, 2392, 10.1128/AAC.34.12.2392 Sime, 2014, Altered pharmacokinetics of piperacillin in febrile neutropenic patients with haematological malignancy, Antimicrob Agents Chemother, 58, 3533, 10.1128/AAC.02340-14 Brink, 2009, Pharmacokinetics of once-daily dosing of ertapenem in critically ill patients with severe sepsis, Int J Antimicrob Agents, 33, 432, 10.1016/j.ijantimicag.2008.10.005 Ulldemolins, 2010, Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics, J Antimicrob Chemother, 65, 1771, 10.1093/jac/dkq184 Yagi, 2013, Plasma exposure of free linezolid and its ratio to minimum inhibitory concentration varies in critically ill patients, Int J Antimicrob Agents, 42, 329, 10.1016/j.ijantimicag.2013.06.015 Yano, 2007, Variability in teicoplanin protein binding and its prediction using serum albumin concentrations, Ther Drug Monit, 29, 399, 10.1097/FTD.0b013e3180690755 Pea, 2006, The effect of multifactorial, multidisciplinary educational interventions on appropriate use of teicoplanin, Int J Antimicrob Agents, 27, 344, 10.1016/j.ijantimicag.2005.11.012 Patsalos, 2008, Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: a position paper by the Subcommission on Therapeutic Drug Monitoring, ILAE Commission on Therapeutic Strategies, Epilepsia, 49, 1239, 10.1111/j.1528-1167.2008.01561.x