Ajmaline blocks I Na and I Kr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters
Tài liệu tham khảo
Agullo-Pascual, 2014, Arrhythmogenic cardiomyopathy and Brugada syndrome: diseases of the connexome, FEBS Lett., 588, 1322, 10.1016/j.febslet.2014.02.008
Antzelevitch, 2007, Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes, AJP Hear. Circ. Physiol., 293, H2024, 10.1152/ajpheart.00355.2007
BAZETT, 1997, An analysis of the time-relations of electrocardiograms, Ann. Noninvasive Electrocardiol., 2, 177, 10.1111/j.1542-474X.1997.tb00325.x
Bébarová, 2005, Effect of ajmaline on transient outward current in rat ventricular myocytes, Gen. Physiol. Biophys., 24, 27
Bezzina, 2013, Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death, Nat. Genet., 45, 1044, 10.1038/ng.2712
Brugada, 1992, Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome, JACC, 20, 1391, 10.1016/0735-1097(92)90253-J
Brugada, 2003, The ajmaline challenge in Brugada syndrome: a useful tool or misleading information?, Eur. Heart J., 24, 1085, 10.1016/S0195-668X(03)00232-X
Brugada, 2015, Brugada syndrome phenotype elimination by epicardial substrate ablation, Circ. Arrhythmia Electrophysiol., 8, 1373, 10.1161/CIRCEP.115.003220
Bu, 2009, Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages, Nature, 460, 113, 10.1038/nature08191
Burridge, 2011, A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability, PLoS One, 6, 10.1371/journal.pone.0018293
Catalano, 2009, Magnetic resonance investigations in Brugada syndrome reveal unexpectedly high rate of structural abnormalities, Eur. Heart J., 30, 2241, 10.1093/eurheartj/ehp252
Coronel, 2005, Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study, Circulation, 112, 2769, 10.1161/CIRCULATIONAHA.105.532614
Doss, 2012, Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr), PLoS One, 7, e40288, 10.1371/journal.pone.0040288
Egashira, 2012, Disease characterization using LQTS-specific induced pluripotent stem cells, Cardiovasc. Res., 95, 419, 10.1093/cvr/cvs206
Fischer, 2013, Inhibition of cardiac Kv1.5 and Kv4.3 potassium channels by the class Ia anti-arrhythmic ajmaline: mode of action, Naunyn Schmiedeberg's Arch. Pharmacol., 386, 991, 10.1007/s00210-013-0901-0
Giacomelli, 2017, Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells, Development, 7
Harris, 2013, Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays, Toxicol. Sci., 134, 412, 10.1093/toxsci/kft113
Hasdemir, 2015, High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia, Heart Rhythm., 12, 1584, 10.1016/j.hrthm.2015.03.015
Ishida, 2016, GFRA2 identifies cardiac progenitors and mediates cardiomyocyte differentiation in a RET-independent signaling pathway, Cell Rep., 16, 1026, 10.1016/j.celrep.2016.06.050
Kiesecker, 2004, Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action, Naunyn Schmiedeberg's Arch. Pharmacol., 370, 423, 10.1007/s00210-004-0976-8
Kosmidis, 2016, Readthrough-promoting drugs gentamicin and PTC124 fail to rescue Na v 1.5 function of human-induced pluripotent stem cell-derived cardiomyocytes carrying nonsense mutations in the sodium channel gene SCN5A, Circ. Arrhythmia Electrophysiol., 9, 10.1161/CIRCEP.116.004227
Lambiase, 2009, High-density substrate mapping in brugada syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis, Circulation, 120, 106, 10.1161/CIRCULATIONAHA.108.771401
Le Scouarnec, 2015, Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for brugada syndrome, Hum. Mol. Genet., 24, 2757, 10.1093/hmg/ddv036
Lek, 2016, Analysis of protein-coding genetic variation in 60,706 humans, Nat. Publ. Gr., 536, 285, 10.1038/nature19057
Liang, 2016, Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome, J. Am. Coll. Cardiol., 68, 2086, 10.1016/j.jacc.2016.07.779
Matsa, 2011, Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation, Eur. Heart J., 32, 952, 10.1093/eurheartj/ehr073
Meregalli, 2005, Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?, Cardiovasc. Res., 10.1016/j.cardiores.2005.03.005
Minami, 2012, A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine-and xeno-free conditions, Cell Rep., 1
Mizusawa, 2012, Brugada syndrome, Circ. Arrhythmia Electrophysiol., 10.1161/CIRCEP.111.964577
Morita, 2003, Site-specific arrhythmogenesis in patients with Brugada syndrome, J. Cardiovasc. Electrophysiol., 14, 373, 10.1046/j.1540-8167.2003.02365.x
Morita, 2008, Repolarization heterogeneity in the right ventricular outflow tract: correlation with ventricular arrhythmias in Brugada patients and in an in vitro canine Brugada model, Heart Rhythm., 5, 725, 10.1016/j.hrthm.2008.02.028
Nademanee, 2011, Prevention of ventricular fibrillation episodes in brugada syndrome by catheter ablation over the anterior right ventricular outflow tract epicardium, Circulation, 123, 1270, 10.1161/CIRCULATIONAHA.110.972612
Nademanee, 2015, Fibrosis, connexin-43, and conduction abnormalities in the Brugada syndrome, J. Am. Coll. Cardiol., 66, 1976, 10.1016/j.jacc.2015.08.862
Okita, 2011, A more efficient method to generate integration-free human iPS cells, Nat. Methods, 8, 409, 10.1038/nmeth.1591
Padrini, 1993, Pharmacokinetics and electrophysiological effects of intravenous Ajmaline, Clin. Pharmacokinet., 25, 408, 10.2165/00003088-199325050-00006
Papavassiliu, 2010, Spontaneous type 1 electrocardiographic pattern is associated with cardiovascular magnetic resonance imaging changes in Brugada syndrome, Heart Rhythm., 7, 1790, 10.1016/j.hrthm.2010.09.004
Pellman, 2016, Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: mechanisms and model systems, J. Mol. Cell. Cardiol., 10.1016/j.yjmcc.2016.03.005
Pradhapan, 2013, Cardiomyocyte MEA data analysis (CardioMDA)--a novel field potential data analysis software for pluripotent stem cell derived cardiomyocytes, PLoS One, 8, e73637, 10.1371/journal.pone.0073637
Priori, 2014, Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes, J. Arrhythmia.
Pua, 2016, Development of a comprehensive sequencing assay for inherited cardiac condition genes, J. Cardiovasc. Transl. Res., 9, 3, 10.1007/s12265-016-9673-5
Qu, Y., Vargas, H.M., 2015. Proarrhythmia risk assessment in human induced pluripotent stem cell-derived cardiomyocytes using the maestro MEA platform 147, 286–295. doi:https://doi.org/10.1093/toxsci/kfv128.
Rolf, 2003, The ajmaline challenge in Brugada syndrome: diagnostic impact, safety, and recommended protocol, Eur. Heart J., 24, 1104, 10.1016/S0195-668X(03)00195-7
Roukoz, 2007, Dofetilide: a new class III antiarrhythmic agent, Expert. Rev. Cardiovasc. Ther., 5, 9, 10.1586/14779072.5.1.9
Sagie, 1992, An improved method for adjusting the QT interval for heart rate (the Framingham heart study), Am. J. Cardiol., 70, 797, 10.1016/0002-9149(92)90562-D
Sala, 2016, vol. 8, 1065
Sarquella-Brugada, 2015, Brugada syndrome: clinical and genetic findings, Genet. Med., 18, 1
Schaaf, 2016, Stem Cell Rep., 7
Schmittgen, 2008, Analyzing real-time PCR data by the comparative CT method, Nat. Protoc., 3, 1101, 10.1038/nprot.2008.73
Somers, 2010, Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette, Stem Cells, 28, 1728, 10.1002/stem.495
Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019
Thavandiran, 2013, Design and formulation of functional pluripotent stem cell-derived cardiac microtissues, Proc. Natl. Acad. Sci. U. S. A., 110, E4698, 10.1073/pnas.1311120110
Tiburcy, 2017, Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair, Circulation, 135, 1832, 10.1161/CIRCULATIONAHA.116.024145
Tohyama, 2013, Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes, Cell Stem Cell, 12, 127, 10.1016/j.stem.2012.09.013
Veerman, 2015, Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?, Stem Cells Dev., 24, 10.1089/scd.2014.0533
Veerman, 2016, hiPSC-derived cardiomyocytes from Brugada syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities, Sci. Rep., 6, 10.1038/srep30967
Wilde, 2013, Genetic testing for inherited cardiac disease, Nat. Rev. Cardiol., 10, 571, 10.1038/nrcardio.2013.108