Airborne bacteria, fungi, and endotoxin levels in residential microenvironments: a case study

Rajasekhar Balasubramanian1, Palaniappan Nainar2, Adharsh Rajasekar1
1Department of Civil and Environmental Engineering, Faculty of Engineering, National University of Singapore, Block EA, 9 Engineering Drive 1, Singapore 117576, Singapore
2Department of Microbiology, Tirunelveli Medical College, Tirunelveli, 627011, India

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Abt, E., Suh, H. H., Allen, G., & Koutrakis, P. (2000). Characterisation of indoor particle sources: A study conducted in the metropolitan Boston area. Environmental Health Perspectives, 108, 35–44.

ACGIH. (1989). Guidelines for the assessment of bioaerosols in the indoor environment. In American Conference of Governmental Industrial Hygienists, Cincinnati, OH.

Alexopoulos, C. J., & Mims, C. W. (1952). Introductory mycology (3rd ed.). USA: John Wiley & Sons Inc.

Andersen, A. A. (1958). New sampler for collection, sizing and enumeration of viable airborne particles. Journal of Bacteriology, 76, 471–484.

ASHRAE Standard-55. (1992). Thermal environment conditions for human occupancy. In American society of heating, refrigerating & air-conditioning engineers, Inc, Atlanta, GA, USA.

Awad, A. H. A. (2007). Airborne dust, bacteria, actinomycetes and fungi at a flourmill. Aerobiologia, 23, 59–69.

Aydogdu, H., Asan, A., Otkun, M. T., & Ture, M. (2005). Monitoring of fungi and bacteria in the indoor air of primary schools in Edirne city, Turkey. Indoor and Built Environment, 14, 411–425.

Brunekreef, B., de Rijk, L., Verhoeff, A. P., & Samson, R. (1990). Classification of dampness in homes. In Indoor Air’90. Proceedings of the 5th International Conference on Indoor Air Quality and Climate, Toronto (pp. 15–20).

Burge, H. A. (1985). Fungus allergens. Clinical Reviews in Allergy, 3, 319–329.

Burge, H. (1990). Bioaerosols: Prevalence and health effects in the indoor environment. Journal of Allergy and Clinical Immunology, 86, 687–701.

Carty, C. L., Gehring, U., Cyrys, J., Bischof, W., & Heinrich, J. (2003). Seasonal variability of endotoxin in ambient fine particulate matter. Journal of Environmental Monitoring, 5, 953–958.

Desai, M. R., & Ghosh, S. K. (2003). Occupational exposure to airborne fungi among ricemill workerswith special reference to aflatoxin producing A-flavus strains. Annals of Agricultural and Environmental Medicine, 10, 159–162.

Douwes, J., Versloot, P., Hollander, A., Heederik, D., & Doekes, G. (1995). Influence of various dust sampling and extraction methods on the measurement of airborne endotoxin. Applied and Environmental Microbiology, 61, 1763–1769.

Dowd, S. E., & Maier, R. M. (2000). Aeromicrobiology. In R. M. Maier, I. L. Pepper, & C. P. Gerba (Eds.), Environmetal microbiology (pp. 91–122). San Diego: Academic.

Ellis, J. J. (1981). The effect of medium temperature and age on Rhizopus delemar sporangiospore size. Mycologia, 73, 362–368.

Gehring, U., Bischof, W., Fahlbusch, B., Wichmann, H. E., & Heinrich, J. (2002). House dust endotoxin and allergic sensitization in children. American Journal of Respiratory and Critical Care Medicine, 166, 939–944.

Gehring, U., Bolte, G., Borte, M., Bischof, W., Fahlbusch, B., Wichmann, H. E., et al. (2001). Exposure to endotoxin decreases the risk of atopic eczema in infancy: A cohort study. Journal of Allergy and Clinical Immunology, 108, 847–854.

Gereda, J. E., Klinnert, M. D., Price, R., Leung, Y. M. D., & Liu, H. A. (2001). Metropolitan home living conditions associated with indoor endotoxin levels. Journal of Allergy and Clinical Immunology, 107, 790–796.

Gorny, R. L., Dutkiewicz, J., & Krysiska-Traczyk, E. (1999). Size distribution of bacterial and fungal bioaerosols in indoor air. Annals of Agriculture and Environmental Medicine, 6, 105–113.

Griffiths, W. D., & DeCosemo, G. A. L. (1994). The assessment of bioaerosols: A critical review. Journal of Aerosol Science, 25, 1425–1458.

Guo, H., Lee, S. C., & Chan, L. Y. (2004). Indoor air quality investigation at air-conditioned and non-air-conditioned markets in Hong Kong. Science of the Total Environmental, 323, 87–98.

Haas, D., Habib, J., Galler, H., Buzina, W., Schlacher, R., Marth, E., et al. (2007). Assessment of indoor air in Austrian apartments with and without visible mold growth. Atmospheric Environment, 41, 5192–5201.

Hameed, A. A. A., Shakour, A. A., & Yasser, H. I. (2003). Evaluation of bio-aerosols at an animal feed manufacturing industry: A case study. Aerobiologia, 19, 1573–3025.

Heederik, D., Brouwer, R., Biersteker, K., & Boleij, J. S. M. (1991). Relationship of airborne endotoxin and bacteria levels in pig farms with the lung function and respiratory symptoms of farmers. International Archives of Occupational and Environmental Health, 62, 595–601.

Heinrich, J., Pitz, M., Bischof, W., Krug, N., & Borm, P. J. A. (2003). Endotoxin in fine (PM2.5) and coarse (PM2.5–10) particle mass of ambient aerosols. A temporo-spatial analysis. Atmospheric Environment, 37, 3659–3667.

Hsu, N. Y., Chen, P. Y., Chang, H. W., & Su, H. J. (2011). Changes in profiles of airborne fungi in flooded homes in southern Taiwan after Typhoon Moraket. Science of the Total Environment, 409, 1677–1682.

Hunter, C. A., Grant, C., Flannigan, B., & Bravery, A. F. (1988). Mould in buildings: The air spora of domestic dwellings. International Biodeterioration, 24, 81–101.

Hunter, C. A., Hull, A. V., Higham, D. F., Grimes, C. P., & Lea, R. G. (1996). Fungi and bacteria. In R. W. Berry, V. M. Brown, S. K. D. Coward, D. R. Crump, M. Gavin, C. P. Grimes, D. F. Higham, A. V. Hull, C. A. Hunter, R. G. Lea, J. W. Llewellyn, & G. J. Raw (Eds.), Indoor air quality in homes: The building research establishment indoor environment study (pp. 99–117). Wartford: Building Research Establishment.

Jothish, P. S., & Nayar, T. S. (2004). Airborne fungal spores in a sawmill environment in Palakkad District, Kerala, India. Aerobiologia, 20, 75–81.

Karlsson, K., & Malmberg, P. (1989). Characterisation of exposure to moulds and actinomycetes in agricultural dusts by scanning electron microscopy. Scandinavian Journal of Work and Environmental Health, 5, 353–359.

Kim, K. Y., & Kim, C. N. (2007). Airborne microbiological characteristics in public buildings of Korea. Building and Environment, 42, 2188–2196.

Kullman, G. J., Thorne, P. S., Waldron, P. F., Marx, J. J., Ault, B., Lewis, D. M., Siegel, P. D., Olenchock S. A., & Merchant, J. A. (1998). Organic dust exposures from work in diary barns. American Industrial Hygiene Association Journal, 59, 403–414.

Lacey, J., & Dutkiewicz, J. (1994). Bioaerosols and occupational lung-disease. Journal of Aerosol Science, 25, 1371–1404.

Lee, S. (2010). Prevalence of childhood asthma in Korea: International study of asthma and allergies in childhood. Allergy Asthma Immunol Res, 2, 61–64.

Lee, K. Y. A., Chan, C. K., Fang, M., & Lau, P. S. A. (2004). The 3-hydroxy fatty acids as biomarkers for quantification and characterisation of endotoxins and gram-negative bacteria in atmospheric aerosols in Hong Kong. Atmospheric Environment, 38, 6307–6317.

Lee, J. H., & Jo, W. K. (2006). Characteristics of indoor and outdoor bioaerosols at Korean high-rise apartment buildings. Environmental Research, 101, 11–17.

Li, C. S., & Kuo, Y.-M. (1993). Characteristics of indoor viable fungi in Taiwan. In Indoor Air’93. Proceedings of the 6th International Conference on Indoor Air Quality and Climate, Helsinki (pp. 183–187).

Liao, V. H., Chio, C. P., Chou, W. C., Ju, Y. R., & Liao, C. M. (2010). Modeling human health risks of airborne endotoxin in homes during the winter and summer seasons. Science of the Total Environment, 408, 1530–1537.

Lim, T. K. (2003). Overview of asthma care in Singapore. The Singapore Family Physician, 29, 7–8.

Long, M. C., Suh, H. H., Kobzik, L., Catalano, P. J., Ning, Y. Y., & Koutrakis, P. (2001). A pilot investigation of the relative toxicity of indoor and outdoor fine particles: In vitro effects of endotoxin and other particulate properties. Environmental Health Perspectives, 109, 1019–1026.

Meklin, T., Hyvärinen, A., Toivola, M., Reponen, T., Koponen, V., Husman, T., et al. (2003). Effect of building frame and moisture damage on microbiological indoor air quality in school buildings. American Industrial Hygiene Association Journal, 64, 108–116.

Michel, O., Ginanni, R., Duchateau, J., Vertongen, F., Le Bon, B., & Sergysels, R. (1991). Domestic endotoxin exposure and clinical severity of asthma. Clinical and Experimental Allergy, 21, 441–448.

Michel, O., Ginanni, R., & Sergysels, R. (1992). Relation between the bronchial obstractive response to inhaled lipopolysaccharide and bronchial responsiveness to histamine. Thorax, 47, 288–291.

Michel, O., Kips, J., Duchateau, J., Vertongen, F., Robert, L., Collet, H., et al. (1996). Severity of asthma is related to endotoxin in house dust. American Journal of Respiratory Critical Care and Medicine, 154, 1641–1646.

Moschandreas, D. J., Cha, D. K., & Qian, J. (1996). Measurement of indoor bioaerosol levels by direct counting method. Journal of Environmental Engineering, 122, 374–378.

Muilenberg, M. L. (1995). The outdoor aerosols. In H. A. Burge (Ed.), Bioaerosols, indoor air research series (p. 163). Boca Raton, Florida, USA: CRC Press, Inc.

Musk, A. W., Venables, K. M., Crook, B., Nunn, A. J., Hawkins, R., & Crook, G. D. W. (1989). Respiratory symptoms, lung-function, and sensitization to flour in a British bakery. British Journal of Industrial medicine, 46, 636–642.

NEA. (1996). Indoor air quality guidelines. In Guidelines for good indoor air quality in office premises (1st ed.). Singapore: National Environmental Agency. http://app2.nea.gov.sg/airquality_guidelines.aspx .

Ng, T. P., & Tan, W. C. (1999). Temporal trends and ethnic variations in asthma mortality in Singapore, 1976–1995. Thorax, 54, 990–994.

Nilsson, S., Merritt, A. S., & Bellander, T. (2011). Endotoxins in urban air in Stockholm, Swedan. Atmospheric Environment, 45, 266–270.

NUH. (2002). The NUH Children’s Medical Institute (CMI) launches “I CAN!” programme for children suffering from asthma and allergies in Singapore. http://www.nuh.com.sg/wbn/slot/u1756/bulletins/bulletin_2.8.pdf .

NUH. (2003). Asia-Pacific specialists in asthma and allergies to look into increasing number of children suffering from asthma and allergies. http://www.nuh.com.sg/wbn/slot/u1753/Patients%20and%20Visitors/Media%20Releases/2003/24%20Nov%2003.pdf .

Oppliger, A., Rusca, S., Charriere, N., Duc, T. V., & Droz, P. O. (2005). Assessment of bioaerosols and inhalable dust exposure in Swiss sawmills. Annals of Occupational Hygiene, 49, 385–391.

Osornio-Vargas, A. R., Bonner, J. C., Alfaro-Moreno, E., Martinez, L., Garcia-Cuellar, C., Rosales, S. P., et al. (2003). Proinflammtory and cytotoxic effects of Mexico city air pollution particulate matter in vitro are dependent on particle size and composition. Environmental Health Perspectives, 111, 1289–1294.

Owen, M. K., Ensor, D. S., & Sparks, L. (1992). Airborne particle sizes and sources found in indoor air. Atmospheric Environmental Part A-General Topics, 26, 2149–2162.

Palmgren, U., Ström, G., Blomquist, G., & Malmberg, P. (1986). Collection of airborne microorganisms on nucleopore filters, estimation and analysis-CAMNEA method. Journal of Applied Bacteriology, 61, 401–406.

Park, J. H., Spiegelman, D. L., Burge, H., Gold, D. R., Chew, G. L., & Milton, D. K. (2000). Longitudinal study of dust and airborne endotoxin in the home. Environmental Health Perspectives, 109, 859–864.

Park, J. H., Spiegelman, D. L., Gold, D. R., Burge, H. A., & Milton, D. K. (2001). Predictors of airborne endotoxin in the home. Environmental Health and Perspectives, 109, 859–864.

Park, C. W., Yoon, K. Y., Kim, Y. D., Park, J. H., & Hwang, J. (2011). Effects of condensational growth on culturability of airborne bacteria: Implications for sampling and control of bioaerosols. Journal of Aerosol Science, 42, 213–223.

Pasanen, A. L. (1992). Airborne mesophilic fungal spores in various residential environments. Atmospheric Environmental Part A-General Topics, 26, 2861–2868.

Pasanen, A. L., Kasanen, J. P., Rautiala, S., Ikaheimo, M., Rantamaki, J., & Kaariainen, H. (2000). Fungal growth and survival in building materials under fluctuating moisture and temperature conditions. International Biodeterioration and Biodegadation, 46, 117–127.

Platts-Mills, T. A. E., Custis, N. J., Woodfolk, J. A., & Platts-Mills, T. A. E. (2005). Airborne endotoxin in homes with domestic animals: Implications for cat-specific tolerance. Journal of Allergy and Clinical Immunology, 116, 384–389.

Rennie, D. C., Lawson, J. A., Kirychuk, S. P., Paterson, C., Willson, P. J., Senthilselvan, A., et al. (2008). Assessment of endotoxin levels in the home and current asthma and wheeze in school-age children. Indoor Air, 18, 447–453.

Reponen, T., Hyvarinen, A., Ruuskanen, J., Raunemaa, T., & Nevalainen, A. (1994). Comparison of concentrations and size distributions of fungal spores in buildings with and without mold problems. Journal Aerosol Science, 25, 1595–1603.

Reponen, T., Hyvärinen, A., Ruuskanen, J., Raunemaa, T., & Nevlalainen, A. (1993). Size distribution of fungal spores in houses with mould problems. In Indoor Air’93. Proceedings of the 6th International Conference on Indoor Air Quality and Climate, Helsinki (pp. 183–187).

Reponen, T., Willeke, K., Ginshpun, S., & Nevlalainen, A. (2001). Biological particle sampling. In P. A. Baron & K. Willeke (Eds.), Aerosol measurement. Hoboken, New Jersey, USA: John Wiley & sons Inc.

Reynolds, S. J., Thorne, P. S., Donham, K. J., Croteau, E. A., et al. (2002). Comparison of endotoxin assays using agricultural dusts. American Industrial Hygiene Assoc Journal, 63, 430–438.

Rolka, H., Krajewska-Kulak, E., Lukaszuk, C., Oksiejczuk, E., Jakoniuk, P., Leszczynska, K., et al. (2005). Indoor air studies of fungi contamination of social welfare home in Czerewki in north-east part of Poland. Roczniki Akademii Medycznej w Bialymstoku, 50(Suppl 1), 26–30.

Rosas, I., Calderon, C., Salinas, E., Martınez, L., Alfaro-Moreno, E., & Milton, D. K. (2001). Animal and worker exposure to dust and biological particles in animal care houses. Aerobiologia, 17, 49–59.

Rylander, R. (2002). Endotoxin in the environment—exposure and effects. Journal of Endotoxin Research, 8, 241–252.

Rylander, R., Bake, B., Fischer, J. J., & Helander, I. M. (1989). Pulmonary function and symptoms after inhalation of endotoxin. American Review of Respiratory Disease, 140, 981–986.

Savino, E., & Caretta, G. (1992). Airborne fungi in an Italian rice mill. Aerobiologia, 8, 267–275.

Schram-Bijkerk, D., Doekes, G., Douwes, J., Boeve, M., Riedler, J., Üblagger, E., et al. (2005). Bacterial and fungal agents in house dust and wheez in children: The PARSIFAL study. Clinical and Experimental Allergy, 35, 1272–1278.

Shelton, B. G., Kirkland, K. H., Flanders, W. D., & Morris, G. K. (2002). Profiles of airborne fungi in buildings and outdoor environments in the United States. Applied and Environmental Microbiology, 68, 1743–1753.

Singh, A., & Singh, A. B. (1994). Airborne fungi in a bakery and the prevalence of respiratory dysfunction among workers. Grana, 33, 349–358.

Sly, R. M. (1988). Mortality from asthma, 1979–1984. Journal of Allergy and Clinical Immunology, 82, 705–717.

Sneath, P. H. A., Mair, N. S., Sharpe, M. E., & Holt, J. G. (1986). Bergey’s manual of systematic bacteriology. Baltimore: Williams & Wilkins Inc.

So, S. Y., Ng, M. M. T., & Ip, M. M. S. (1990). Rising asthma mortality in Hong Kong, 1976–85. Respiratory Medicine, 84, 457–467.

Su, H. J., Wu, P. C., Chen, H. L., Lee, F. C., & Lin, L. L. (2001). Exposure assessment of indoor allergens, endotoxin, and airborne fungi for homes in southern Taiwan. Environmental Research, 85, 135–144.

Sykes, P., Morris, R. H. K., Allen, J. A., Wildsmith, J. D., & Jones, K. P. (2011). Workers’ exposure to dust, endotoxin and β-(1–3) glucan at four large-scale composting facilities. Waste Management, 31, 423–430.

Thorne, P. S., Cohn, R. D., Mav, D., Arbes, S. J., & Zeldin, D. C. (2009). Predictors of endotoxin levels in U.S. housing. Environmental Health Perspectives, 117, 763–771.

Thorne, P. S., & DeKoster, J. A. (1996). Environmental assessment of aerosols, bioaerosols and airborne endotoxins in a machining plant. American Industrial Hygiene Association Journal, 57, 1163–1167.

Thorne, P. S., Reynolds, S. J., Milton, D. K., & Bloebaum, P. D. (1997). Field evaluation of endotoxin air sampling assay methods. American Industrial Hygiene Association Journal, 58, 792–799.

Zorman, T., & Jersek, B. (2008). Assessment of bioaerosol concentrations in different indoor environments. Indoor Built Environment, 17, 155–163.

Zucker, B. A., & Muller, W. (2004). Airborne endotoxins and airborne grame-negative bacteria in a residential neighborhood. Water, Air, and Soil pollution, 158, 67–75.

Zuraimi, M. S., & Tham, K. W. (2008). Indoor air quality and its determinants in tropical child care centers. Atmospheric Environment, 42, 2225–2239.