Air pollution and chronic obstructive pulmonary disease

Chronic Diseases and Translational Medicine - Tập 6 - Trang 260-269 - 2020
Rui-Rui Duan1,2,3,4, Ke Hao5, Ting Yang1,2,3,4
1Peking University China-Japan Friendship School of Clinical Medicine, Beijing 100029, China
2Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, 100029, China
3National Clinical Research Center for Respiratory Diseases, Beijing 100029, China
4Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing 100029, China
5Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA

Tóm tắt

AbstractThere is considerable epidemiological evidence indicating that air pollution has adverse effects on human health and is closely related to respiratory diseases, including chronic obstructive pulmonary disease (COPD). These effects, which can be divided into short‐ and long‐term effects, can manifest as an exacerbation of existing symptoms, impaired lung function, and increased hospitalization and mortality rates. Long‐term exposure to air with a high concentration of pollutants may also increase the incidence of COPD. The combined effects of different pollutants may become more complex in the future; hence, there is a need for more intensive research on specific at‐risk populations, and formulating corresponding protective strategies is crucial. We aimed to review the epidemiological evidence on the effect of air pollution on COPD, the possible pathophysiological mechanisms underlying this effect, as well as protective measures against the effects of air pollutants in patients with COPD.

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Chronic Diseases and Translational Medicine

Tập 6

260-269

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