Aging Biology and Novel Targets for Drug Discovery

Journals of Gerontology - Series A Biological Sciences and Medical Sciences - Tập 67A Số 2 - Trang 168-174 - 2012
David G. Le Couteur1,2, Andrew J. McLachlan2,3, Ronald J. Quinn4, Stephen J. Simpson5, Rafael de Cabo6
1ANZAC Research Institute, Concord Hospital, University of Sydney, Australia
2Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Australia
3Faculty of Pharmacy, University of Sydney, Australia
4Eskitis Institute, Griffith University, Brisbane, Australia
5School of Biological Sciences, University of Sydney, Australia
6Laboratory for Experimental Gerontology, National Institute on Aging, Baltimore, Maryland

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Tài liệu tham khảo

Munos, 2009, Nature reviews. Drug discovery, 8, 959, 10.1038/nrd2961

Paul, 2010, Nature reviews. Drug discovery, 9, 203, 10.1038/nrd3078

2007, Nature reviews. Drug discovery, 6, 187, 10.1038/nrd2275

Kenyon, 2010, Nature; Physical Science (London), 464, 504, 10.1038/nature08980

Sinclair, 2006, Scientific American, 294, 48, 10.1038/scientificamerican0306-48

Macarron, 2006, Drug discovery today, 11, 277, 10.1016/j.drudis.2006.02.001

Mayr, 2009, Current opinion in pharmacology, 9, 580, 10.1016/j.coph.2009.08.004

Overington, 2006, Nature reviews. Drug discovery, 5, 993, 10.1038/nrd2199

Kessel, 2006, Nature reviews. Drug discovery, 5, 985, 10.1038/nrd2203

Mor, 2005, Journal of the American Geriatrics Society, 53, S308, 10.1111/j.1532-5415.2005.53496.x

2006, The Scientist, 20, 28

OLSHANSKY, 2007, Annals of the New York Academy of Sciences, 1114, 11, 10.1196/annals.1396.050

Welch, 1996, Annals of Internal Medicine, 124, 577, 10.1001/archinte.156.5.577

2010, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 65, 693

2011, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 66, 179

1956, Journal of Gerontology, 11, 298, 10.1093/geronj/11.3.298

Finkel, 2000, Nature; Physical Science (London), 408, 239, 10.1038/35041687

Sohal, 1996, Science, 273, 59, 10.1126/science.273.5271.59

Sastre, 2003, Free radical biology & medicine, 35, 1, 10.1016/S0891-5849(03)00184-9

1961, Journal of Gerontology, 16, 247, 10.1093/geronj/16.3.247

Yoshihara, 2010, 67, 103, 10.1016/j.maturitas.2010.05.001

Perez, 2009, Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology, 1790, 1005, 10.1016/j.bbagen.2009.06.003

2005, Annals of Internal Medicine, 142, 37, 10.7326/0003-4819-142-1-200501040-00110

Brown-Borg, 2007, Ageing research reviews, 6, 28, 10.1016/j.arr.2007.02.005

Nass, 2007, Endocrinology and metabolism clinics of North America, 36, 233, 10.1016/j.ecl.2006.08.004

2009, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 64A, 1039, 10.1093/gerona/glp091

Liu, 2007, Annals of Internal Medicine, 146, 104, 10.7326/0003-4819-146-2-200701160-00005

Hersch, 2008, 3, 121

2001, J GERONTOL A BIOL SCI, 56, 340B, 10.1093/gerona/56.8.B340

Handelsman, 2006, Medical Journal of Australia, 185, 436, 10.5694/j.1326-5377.2006.tb00642.x

Harman, 2005, Climacteric : the journal of the International Menopause Society, 8, 124, 10.1080/13697130500118001

Kamel, 2006, Cleveland Clinic Journal of Medicine, 73, 1049, 10.3949/ccjm.73.12.1049

2010, New England Journal of Medicine, 363, 109, 10.1056/NEJMoa1000485

Bhagra, 2008, 15, 239, 10.1097/MED.0b013e3282fc7049

Olsen, 1965, Nature; Physical Science (London), 206, 307, 10.1038/206307b0

Ristow, 2010, Experimental gerontology, 45, 410, 10.1016/j.exger.2010.03.014

Ingram, 2006, Aging cell, 5, 97, 10.1111/j.1474-9726.2006.00202.x

2008, PNAS, 105, 2498, 10.1073/pnas.0710787105

Simpson, 2007, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 62, 707, 10.1093/gerona/62.7.707

2009, AGING ALBANY NY, 1, 875, 10.18632/aging.100098

2010, Journal of Gerontology, 65, 695

INGRAM, 2004, Annals of the New York Academy of Sciences, 1019, 412, 10.1196/annals.1297.074

McCay, 1935, The Journal of Nutrition, 10, 63, 10.1093/jn/10.1.63

McCay, 1928, Science, 67, 249, 10.1126/science.67.1731.249

McCay, 1939, The Journal of Nutrition, 18, 1, 10.1079/BJN19640001

Holliday, 1989, BioEssays : news and reviews in molecular, cellular and developmental biology, 10, 125, 10.1002/bies.950100408

Sinclair, 2005, Mechanisms of ageing and development, 126, 987, 10.1016/j.mad.2005.03.019

Sharp, 2011, Cellular and molecular life sciences : CMLS, 68, 587, 10.1007/s00018-010-0542-0

Fontana, 2010, Science, 328, 321, 10.1126/science.1172539

Baur, 2010, Mechanisms of ageing and development, 131, 261, 10.1016/j.mad.2010.02.007

Anisimov, 2003, Experimental gerontology, 38, 1041, 10.1016/S0531-5565(03)00169-4

1998, Journal of anti-aging medicine, 1, 327, 10.1089/rej.1.1998.1.327

Minor, 2010, Toxicology and applied pharmacology, 243, 332, 10.1016/j.taap.2009.11.025

2005, Physiological Genomics, 23, 343, 10.1152/physiolgenomics.00069.2005

Poels, 2009, BioEssays : news and reviews in molecular, cellular and developmental biology, 31, 944, 10.1002/bies.200900003

2010, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 65, 468

Kola, 2004, Nature reviews. Drug discovery, 3, 711, 10.1038/nrd1470

Lin, 2000, Science, 289, 2126, 10.1126/science.289.5487.2126

Howitz, 2003, Nature; Physical Science (London), 425, 191, 10.1038/nature01960

Wood, 2004, Nature; Physical Science (London), 430, 686, 10.1038/nature02789

Baur, 2006, Nature; Physical Science (London), 444, 337, 10.1038/nature05354

Pearson, 2008, 8, 157, 10.1016/j.cmet.2008.06.011

2011, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 66, 264

Milne, 2007, Nature; Physical Science (London), 450, 712, 10.1038/nature06261

Li, 2008, 8, 38, 10.1016/j.cmet.2008.05.004

Boily, 2009, Oncogene, 28, 2882, 10.1038/onc.2009.147

Zoncu, 2011, Nature reviews. Molecular cell biology, 12, 21, 10.1038/nrm3025

Kapahi, 2010, 11, 453, 10.1016/j.cmet.2010.05.001

2010, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 65, 577

Harrison, 2009, Nature; Physical Science (London), 460, 392, 10.1038/nature08221

2011, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 66, 191

Kirken, 2003, Transplantation proceedings, 35, 227S, 10.1016/S0041-1345(03)00230-6

Dancey, 2010, 7, 209, 10.1038/nrclinonc.2010.21

Masoro, 1998, Experimental gerontology, 33, 61, 10.1016/S0531-5565(97)00071-5

Rattan, 2008, Ageing research reviews, 7, 63, 10.1016/j.arr.2007.03.002

Bourg, 2009, Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology, 1790, 1030, 10.1016/j.bbagen.2009.01.004

Mattson, 2008, Ageing research reviews, 7, 43, 10.1016/j.arr.2007.08.004

Calabrese, 2003, Critical reviews in toxicology, 33, 407, 10.1080/713611043

Sagan, 1989, Science, 245, 574, 10.1126/science.2669125

Schrattenholz, 2008, Current medicinal chemistry, 15, 1520, 10.2174/092986708784638843

Athar, 2009, Archives of Biochemistry and Biophysics, 486, 95, 10.1016/j.abb.2009.01.018

Baynes, 2001, Experimental gerontology, 36, 1527, 10.1016/S0531-5565(01)00138-3

Chen, 2003, Experimental gerontology, 38, 1051, 10.1016/S0531-5565(03)00186-4

Tucker, 2002, Drug discovery today, 7, S125, 10.1016/S1359-6446(02)02409-1

2008, AGE DORDR, 30, 187, 10.1007/s11357-008-9048-1

Ingram, 2001, Experimental gerontology, 36, 1025, 10.1016/S0531-5565(01)00110-3

Simm, 2010, Experimental gerontology, 45, 731, 10.1016/j.exger.2010.08.006

Sprott, 2010, Experimental gerontology, 45, 2, 10.1016/j.exger.2009.07.008

2009, AGING ALBANY NY, 1, 281, 10.18632/aging.100034

McLean, 2004, Pharmacological Reviews, 56, 163, 10.1124/pr.56.2.4

Hilmer, 2007, Fundamental & clinical pharmacology, 21, 217, 10.1111/j.1472-8206.2007.00473.x

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Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Tập 67A Số 2

168-174

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