Aggregation-induced emission probes for cancer theranostics

Drug Discovery Today - Tập 22 - Trang 1288-1294 - 2017
Meng Gao1, Ben Zhong Tang1,2
1Guangdong Innovative Research Team, State Key Laboratory of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, China
2Department of Chemistry and Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China

Tài liệu tham khảo

Idee, 2013, Theranostics and contrast-agents for medical imaging: a pharmaceutical company viewpoint, Quant. Imaging Med. Surg., 3, 292 Chi, 2014, Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology, Theranostics, 4, 1072, 10.7150/thno.9899 Luo, 2011, A review of NIR dyes in cancer targeting and imaging, Biomaterials, 32, 7127, 10.1016/j.biomaterials.2011.06.024 Lim, 2016, The nanoscale rainbow, Nature, 531, 26, 10.1038/531026a Luo, 2001, Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole, Chem. Commun., 1740, 10.1039/b105159h Mei, 2014, Aggregation-induced emission: the whole is more brilliant than the parts, Adv. Mater., 26, 5429, 10.1002/adma.201401356 Mei, 2015, Aggregation-induced emission: together we shine, united we soar!, Chem. Rev., 115, 11718, 10.1021/acs.chemrev.5b00263 Wang, 2015, Red emissive AIE nanodots with high two-photon absorption efficiency at 1040nm for deep-tissue in vivo imaging, Biomed. Opt. Express, 6, 3783, 10.1364/BOE.6.003783 Yue, 2015, RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vasculature imaging, Org. Biomol. Chem., 13, 10716, 10.1039/C5OB01536G Hu, 2014, Mitochondria-targeted cancer therapy using a light-up probe with aggregation-induced emission characteristics, Angew. Chem. Int. Ed., 53, 14225, 10.1002/anie.201408897 Wallace, 2012, Mitochondria and cancer, Nat. Rev. Cancer, 12, 685, 10.1038/nrc3365 Shin, 2016, Mitochondria-targeted aggregation induced emission theranostics: crucial importance of in situ activation, Chem. Sci., 7, 6050, 10.1039/C6SC02236G Reedy, 2016, Synthesis and evaluation of tetraarylethylene-based mono-, bis-, and tris(pyridinium) derivatives for image-guided mitochondria-specific targeting and cytotoxicity of metastatic melanoma cells, Bioconjug. Chem., 27, 2424, 10.1021/acs.bioconjchem.6b00394 Zhao, 2016, A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells, Nanoscale, 8, 12520, 10.1039/C5NR08782A Yuan, 2014, Targeted theranostic platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ, J. Am. Chem. Soc., 136, 2546, 10.1021/ja411811w Yuan, 2014, A targeted theranostic platinum(IV) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation, Chem. Commun., 50, 3868, 10.1039/c3cc49516g Xue, 2014, Spatiotemporal drug release visualized through a drug delivery system with tunable aggregation-induced emission, Adv. Mater., 26, 712, 10.1002/adma.201302365 Chen, 2016, Zwitterionic phosphorylcholine-TPE conjugate for pH-responsive drug delivery and AIE active imaging, ACS Appl. Mater. Interfaces, 8, 21185, 10.1021/acsami.6b06071 Zhang, 2014, Imaging intracellular anticancer drug delivery by self-assembly micelles with aggregation-induced emission (AIE micelles), ACS Appl. Mater. Interfaces, 6, 5212, 10.1021/am5005267 Wang, 2015, A pH-responsive drug delivery system with an aggregation-induced emission feature for cell imaging and intracellular drug delivery, Polym. Chem., 6, 4715, 10.1039/C5PY00584A Wang, 2016, Fabrication of pH-responsive nanoparticles with an AIE feature for imaging intracellular drug delivery, Biomacromolecules, 17, 2920, 10.1021/acs.biomac.6b00744 Wu, 2014, In vivo and in situ tracking cancer chemotherapy by highly photostable nir fluorescent theranostic prodrug, J. Am. Chem. Soc., 136, 3579, 10.1021/ja412380j Zhang, 2016, Fluorescent metallacycle-cored polymers via covalent linkage and their use as contrast agents for cell imaging, Proc. Natl. Acad. Sci. U. S. A., 113, 11100, 10.1073/pnas.1612898113 Ding, 2015, A fluorescent light-up nanoparticle probe with aggregation-induced emission characteristics and tumor-acidity responsiveness for targeted imaging and selective suppression of cancer cells, Mater. Horiz., 2, 100, 10.1039/C4MH00164H Huang, 2016, Emissive nanoparticles from pyridinium-substituted tetraphenylethylene salts: imaging and selective cytotoxicity towards cancer cells in vitro and in vivo by varying counter anions, Chem. Sci., 7, 7013, 10.1039/C6SC02395A Wang, 2016, Aggregation induced emission fluorogens based nanotheranostics for targeted and imaging-guided chemo–photothermal combination therapy, Small, 12, 6568, 10.1002/smll.201601473 Macdonald, 2001, Basic principles of photodynamic therapy, J. Porphyrins Phthalocyanines, 5, 105, 10.1002/jpp.328 Bennett, 1989, Singlet oxygen formation in monomeric and aggregated porphyrin c, J. Photochem. Photobiol. B, 3, 81, 10.1016/1011-1344(89)80022-3 Gui, 2017, AIE-active theranostic system: selective staining and killing of cancer cells, Chem. Sci., 8, 1822, 10.1039/C6SC04947H Li, 2017, One-step formulation of targeted aggregation-induced emission dots for image-guided photodynamic therapy of cholangiocarcinoma, ACS Nano, 11, 3922, 10.1021/acsnano.7b00312 Yuan, 2015, Cancer therapy: smart probe for tracing cancer therapy: selective cancer cell detection, image-guided ablation, and prediction of therapeutic response in situ, Small, 11 Han, 2015, Ratiometric biosensor for aggregation-induced emission-guided precise photodynamic therapy, ACS Nano, 9, 10268, 10.1021/acsnano.5b04243 Hu, 2014, Targeted bioimaging and photodynamic therapy of cancer cells with an activatable red fluorescent bioprobe, Anal. Chem., 86, 7987, 10.1021/ac502103t Zhang, 2016, Real-time specific light-up sensing of transferrin receptor: image-guided photodynamic ablation of cancer cells through controlled cytomembrane disintegration, Anal. Chem., 88, 4841, 10.1021/acs.analchem.6b00524 Yuan, 2015, Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells, Angew. Chem. Int. Ed., 54, 1780, 10.1002/anie.201408476 Yu, 2017, Mitochondrion-anchoring photosensitizer with aggregation-induced emission characteristics synergistically boosts the radiosensitivity of cancer cells to ionizing radiation, Adv. Mater., 10.1002/adma.201770103 Chen, 2017, AIEgen-based theranostic system: targeted imaging of cancer cells and adjuvant amplification of antitumor efficacy of paclitaxel, Chem. Sci., 8, 2191, 10.1039/C6SC03859J Hu, 2015, Aggregation-induced emission (AIE) dye loaded polymer nanoparticles for gene silencing in pancreatic cancer and their in vitro and in vivo biocompatibility evaluation, Nano Res., 8, 1563, 10.1007/s12274-014-0642-5 Jin, 2016, Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy, Chem. Commun., 52, 2752, 10.1039/C5CC07818K Yuan, 2015, A photoactivatable AIE polymer for light-controlled gene delivery: concurrent endo/lysosomal escape and DNA unpacking, Angew. Chem. Int. Ed., 54, 11419, 10.1002/anie.201503640