Age-related macular degeneration and cognitive impairment show similarities in changes of neutral lipids in peripheral blood mononuclear cells

Experimental Eye Research - Tập 124 - Trang 11-16 - 2014
Enrico Peiretti1, Antonella Mandas2, Claudia Abete2, Michela Vinci1, Stefania Piludu1, Maura Casu1, Giulia Caminiti1, Sandra Dessì2, Maurizio Fossarello1
1Department of Surgical Sciences, Eye Clinic, University of Cagliari, Cagliari, Italy
2Internal Medical Sciences, University of Cagliari, Cagliari, Italy

Tài liệu tham khảo

Adler, 1999, Cell death in age related macular degeneration, Mol. Vis., 5, 31 Anchisi, 2012, Cholesterol homeostasis: a key to prevent or slow down neurodegeneration, Front. Physiol., 3, 486 Baker, 2009, Early age-related macular degeneration, cognitive function, and dementia: the Cardiovascular Health Study, Arch. Ophthalmol., 127, 667, 10.1001/archophthalmol.2009.30 Botti, 1991, Concentrations of pravastatin and lovastatin in cerebrospinal fluid in healthy subjects, Clin. Neuropharmacol., 14, 256, 10.1097/00002826-199106000-00010 Bretillon, 2008, ApoBlOO, LDLR -/- mice exhibit reduced electroretinographic response and cholesteryl esters deposits in the retina, Investig. Ophthalmol. Vis. Sci., 49, 1307, 10.1167/iovs.07-0808 Bretillon, 2008, Lipid and fatty acid profile of the retina, retinal pigment epithelium/choroid, and lacrimal gland, and associations with adipose tissue fatty acids in human subjects, Exp. Eye Res., 87, 521, 10.1016/j.exer.2008.08.010 Butterfield, 2002, Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists, J. Alzheimer Dis., 4, 193, 10.3233/JAD-2002-4309 Curcio, 2005, Basal deposits and drusen in eyes with age related maculopathy: evidence for solid lipid particles, Exp. Eye Res., 80, 761, 10.1016/j.exer.2004.09.017 Curcio, 2005, Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy, Exp. Eye Res., 81, 731, 10.1016/j.exer.2005.04.012 Dentchev, 2003, Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas, Mol. Vis., 9, 184 Ding, 2009, Molecular pathology of age-related macular degeneration, Prog. Retin. Eye Res., 28, 1, 10.1016/j.preteyeres.2008.10.001 Esenwah, 2010, Age-related macular degeneration-an emerging and re-emerging eye blinding disease, J. Niger. Optom. Assoc., 16, 40 Ferris, 2005, A simplified severity scale for age-related macular degeneration: AREDS Report No. 18, Arch. Ophthalmol., 123, 1570, 10.1001/archopht.123.11.1570 Fliesler, 2010, The ins and outs of cholesterol in the vertebrate retina, J. Lipid Res., 51, 3399, 10.1194/jlr.R010538 Fliesler, 1993, In vivo biosynthesis of cholesterol in the rat retina, FEBS Lett., 335, 234, 10.1016/0014-5793(93)80736-E Folstein, 1975, Mini Mental State: a practical method for grading the cognitive state of patients for the clinician, J. Psychiatr. Res., 12, 189, 10.1016/0022-3956(75)90026-6 Francis, 1955, Lipids in the retina, J. Comp. Neurol., 103, 355, 10.1002/cne.901030209 Gehlbach, 2012, Statins for age-related macular degeneration, Cochrane Database Syst. Rev., 3, 10.1002/14651858.CD006927.pub3 Green, 1993, Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture, Ophthalmology, 100, 1519, 10.1016/S0161-6420(93)31466-1 Hutter-Paier, 2004, The ACAT inhibitor CP- 113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease, Neuron, 44, 227, 10.1016/j.neuron.2004.08.043 Huttunen, 2008, ACAT as a drug target for Alzheimer's disease, Neurodegener. Dis., 5, 212, 10.1159/000113705 Johnson, 2002, The Alzheimer's Ap-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration, PNAS, 99, 11830, 10.1073/pnas.192203399 Kaarniranta, 2011, Age-related macular degeneration (AMD): Alzheimer's disease in the eye?, J. Alzheimer Dis., 24, 615, 10.3233/JAD-2011-101908 Kishan, 2011, Lipids and age- related macular degeneration, Surv. Ophthalmol., 56, 195, 10.1016/j.survophthal.2010.08.008 Kruth, 1984, Histochemical detection and differentiation of free and esterified cholesterol in swine atherosclerosis using filipin, Exp. Mol. Pathol., 40, 288, 10.1016/0014-4800(84)90046-7 Luibl, 2006, Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers, J. Clin. Investig., 116, 378, 10.1172/JCI25843 Maguire, 2009, Statin use and the incidence of advanced age-related macular degeneration in the complications of age-related macular degeneration prevention trial, Ophthalmology, 116, 2381, 10.1016/j.ophtha.2009.06.055 Malek, 2005, Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration, PNAS, 102, 11900, 10.1073/pnas.0503015102 Mandas, 2012, Changes in cholesterol metabolism related gene expression in peripheral blood mononuclear cells from Alzheimer patients, Lipids Health Dis., 14, 11 Mandas, 2014, Cognitive decline and depressive symptoms in late-life are associated with statin use: evidence from a population-based study of Sardinian old people living in their own home, Neurol. Res., 36, 247, 10.1179/1743132813Y.0000000287 McCarty, 2001, Cholesterol-lowering medications reduce the risk of age-related maculopathy progression, Med. J. Aust., 175, 340, 10.5694/j.1326-5377.2001.tb143604.x Mehlem, 2013, Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease, Nat. Protoc., 8, 1149, 10.1038/nprot.2013.055 Niikura, 2006, Neuronal cell death in Alzheimer's disease and a neuroprotective factor, humanin, Curr. Neuropharmacol., 4, 139, 10.2174/157015906776359577 Pani, 2009, Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease, BMC Med., 2, 7 Pani, 2009, Altered cholesterol ester cycle in skin fibroblasts from patients with Alzheimer's disease, J. Alzheimer Dis., 18, 829, 10.3233/JAD-2009-1193 Peponis, 2010, The controversy over the association between statins use and progression of age-related macular degeneration: a mini review, Clin. Ophthalmol., 4, 865 Puglielli, 2003, Alzheimer's disease: the cholesterol connection, Nat. Neurosci., 6, 345, 10.1038/nn0403-345 Puglielli, 2004, Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein, J. Mol. Neurosci., 24, 93, 10.1385/JMN:24:1:093 Sarks, 1980, Council Lecture. Drusen and their relationship to senile macular degeneration, Aust. J. Ophthalmol., 8, 117, 10.1111/j.1442-9071.1980.tb01670.x VanderBeek, 2013, Role of statins in the development and progression of age-related macular degeneration, Retina, 33, 414, 10.1097/IAE.0b013e318276e0cf Vingerling, 1995, Age- related macular degeneration is associated with atherosclerosis. The Rotterdam Study, Am. J. Epidemiol., 142, 404, 10.1093/oxfordjournals.aje.a117648 Wilson, 2004, Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration, Am. J. Ophthalmol., 137, 615