Age-related Differences in Recall of Information and Handling of Chemotherapy-related Side Effects in Cancer Patients: The ReCap Study

Oncologist - Tập 27 Số 2 - Trang e185-e193 - 2022
Cecilia Margareta Lund1,2, Marta Kramer Mikkelsen3,4, Susann Theile3, Hanne Marie Michelsen3, Martin Schultz1,2, Stéphane Oudard3, Dorte Nielsen5,3
1CopenAge – Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark
2Department of Medicine, Copenhagen University Hospital, Herlev and Gentofte, Copenhagen, Denmark
3Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Copenhagen, Denmark
4Department of Oncology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
5Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark

Tóm tắt

Abstract Background To prevent severe toxicity and hospital admissions, adequate management and recall of information about side effects are crucial and health literacy plays an important role. If age-related factors impact recall of given information and handling of side effects, revised ways to give information are required. Patients and Methods We undertook a questionnaire-based survey among 188 newly diagnosed patients with pancreatic cancer or colorectal cancer and chemo-naive patients with prostate cancer treated with adjuvant or first-line palliative chemotherapy comprising satisfaction with given information, recall of potential side effects, and handling of hypothetical side effect scenarios. We evaluated the association between baseline characteristics, ie, age, frailty (G8 score), comorbidity (Charlson Comorbidity Index), cognitive function (Mini-Cog), satisfaction, recall of information, and handling of side effects. Results Reduced ability to recall information about several side effects (eg, chest pain) was associated with older age (odds ratio adjusted for cancer [aOR] 0.94 [95% CI, 0.88-0.98]) and poor cognitive screening (aOR 0.56 [95% CI, 0.33-0.91]). Insufficient or dangerous handling of side effects was associated with older age (aOR 0.96 (95% CI, 0.92-0.99)) and cognitive impairment (aOR 0.70 [95% CI, 0.50-0.95]). Conclusion Older age and poor cognitive screening may impact patients’ ability to understand and adequately handle chemotherapy-related side effects. Cognitive screening and focus on individual ways to give information including assessment of recall and handling are needed.

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Oncologist

Tập 27 Số 2

e185-e193

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