Advances in the Vascular Pathophysiology of Ischemic Stroke

Thrombosis Research - Tập 98 Số 3 - Trang 73-81 - 2000
Gregory J. del Zoppo1, John M. Hallenbeck2
1Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
2Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.

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Zülch, 1985

Bär, 1972, The formation of capillary basement membranes during internal vascularization of the rat's cerebral cortex, Z Zellforsch, 133, 231, 10.1007/BF00307145

Bär, 1980, The vascular system of the cerebral cortex, Adv Anat Embryol Cell Biol, 59, 1, 10.1007/978-3-642-67432-7_1

Fenstermacher, 1991, Functional variations in parenchymal microvascular systems within the brain, Magn Reson Med, 19, 217, 10.1002/mrm.1910190205

Peters, 1991

Bernstein, 1985, Astrocytes secrete basal lamina after hemisection of rat spinal cord, Brain Res, 327, 135, 10.1016/0006-8993(85)91507-0

Kusaka, 1985, Basal lamina formation by astrocytes in organotypic cultures of mouse spinal cord tissue, J Neuropathol Exp Neurol, 44, 295, 10.1097/00005072-198505000-00007

Nagano, 1993, Extracellular matrix modulates the proliferation of rat astrocytes in serum-free culture, Glia, 8, 71, 10.1002/glia.440080202

Janzer, 1987, Astrocytes induce blood–brain barrier properties in endothelial cells (letter), Nature, 325, 353, 10.1038/325253a0

Tagami, 1992, Morphological differentiation of endothelial cells co-cultured with astrocytes on type-I or type-IV collagen, Cell Tissue Res, 268, 225, 10.1007/BF00318790

Webersinke, 1992, Comparison of gene expression of extracellular matrix molecules in brain microvascular endothelial cells and astrocytes, Biochem Biophys Res Commun, 189, 877, 10.1016/0006-291X(92)92285-6

Hallenbeck, 1998, Inflammatory responses in cerebral ischemia, 489

Hallenbeck, 1988, Stroke risk factors prepare rat brainstem tissues for modified local Schwartzman reaction, Stroke, 19, 863, 10.1161/01.STR.19.7.863

Risau, 1990, Development of the blood–brain barrier, TINS, 13, 174

Okada, 1994, Fibrin contributes to microvascular obstructions and parenchymal changes during early focal cerebral ischemia and reperfusion, Stroke, 25, 1847, 10.1161/01.STR.25.9.1847

Wagner, 1997, Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by α6β4 during focal cerebral ischemia/reperfusion, Stroke, 28, 858, 10.1161/01.STR.28.4.858

Hamann, 1995, Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion, Stroke, 26, 2120, 10.1161/01.STR.26.11.2120

Hamann, 1996, Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion, J Cereb Blood Flow Metab, 16, 1373, 10.1097/00004647-199611000-00036

Takahashi, 1995, Preservation of autoregulatory cerebral vasodilator responses to hypotension after inhibition of nitric oxide synthesis, Brain Res, 678, 21, 10.1016/0006-8993(95)00129-E

Faraci, 1992, Regulation of the cerebral circulation by endothelium, Pharmacol Ther, 56, 1, 10.1016/0163-7258(92)90035-X

Macrae, 1993, Endothelin-1-induced reductions in cerebral blood flow, J Cereb Blood Flow Metab, 13, 276, 10.1038/jcbfm.1993.34

Nag, 1987, Gross pathologic anatomic, 59

del Zoppo, 1992, Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke, Ann Neurol, 32, 78, 10.1002/ana.410320113

del Zoppo, 1998, Proact, Stroke, 29, 4, 10.1161/01.STR.29.1.4

Fieschi, 1989, Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours, J Neurol Sci, 91, 311, 10.1016/0022-510X(89)90060-9

Solis, 1977, Cerebral angiography in acute cerebral infarction, Revist Interam Radiol, 2, 19

Fieschi, 1969, Transient embolic occlusion of the middle cerebral and internal carotid arteries in cerebral apoplexy, J Neurol Neurosurg Psychiatry, 32, 236, 10.1136/jnnp.32.3.236

Irino, 1977, Angiographic manifestations in post-recanalized cerebral infarction, Neurology, 27, 471, 10.1212/WNL.27.5.471

Mori, 1992, Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke, Neurology, 42, 976, 10.1212/WNL.42.5.976

Yamaguchi, 1993, Intravenous tissue plasminogen activator in acute thromboembolic stroke, 59

Fisher, 1951, Observations on brain embolism with special reference to the mechanism of hemorrhagic infarction, J Neuropathol Exp Neurol, 10, 92

Okada, 1989, Hemorrhagic transformation in cerebral embolism, Stroke, 20, 598, 10.1161/01.STR.20.5.598

Hornig, 1986, Hemorrhagic cerebral infarction, Stroke, 17, 179, 10.1161/01.STR.17.2.179

Meyer JS, Gilroy J, Barnhart ME, Johnson JF. Therapeutic thrombolysis in cerebral thromboembolism: randomized evaluation of intravenous streptokinase. In: Millikan CH, Siekert RG, Whisnant JP, editors. Cerebral Vascular Diseases, Fourth Princeton Conference. New York: Grune and Stratton; 1965. p. 200–13.

Babikian, 1989, Intracerebral hemorrhage in stroke patients anticoagulated with heparin, Stroke, 29, 1500, 10.1161/01.STR.20.11.1500

Koller, 1982, Recurrent embolic cerebral infarction and anticoagulation, Neurology, 32, 283, 10.1212/WNL.32.3.283

del Zoppo, 1988, Local intra-arterial fibrinolytic therapy in acute carotid territory stroke. A pilot study, Stroke, 19, 307, 10.1161/01.STR.19.3.307

Mori, 1988, Intracarotid urokinase with thromboembolic occlusion of the middle cerebral artery, Stroke, 19, 802, 10.1161/01.STR.19.7.802

Ogata, 1989, Hemorrhagic infarct of the brain without a reopening of the occluded arteries in cardioembolic stroke, Stroke, 20, 876, 10.1161/01.STR.20.7.876

Rosenberg, 1994, Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain, Lab Invest, 71, 417

Heo, 1999, Matrix metalloproteinases increase very early during experimental focal ischemia, J Cereb Blood Flow Metab, 19, 624, 10.1097/00004647-199906000-00005

Gaetani, 1999, Metalloproteases and intracranial vascular lesions, Neurol Res, 21, 385, 10.1080/01616412.1999.11740948

Carmeliet, 1997, Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation, Nature Genetics, 17, 439, 10.1038/ng1297-439

Tamarina, 1997, Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta, Surgery, 122, 264, 10.1016/S0039-6060(97)90017-9

Risau, 1986, Brain astrocytes induce the expression of an early cell surface marker for blood–brain barrier specific endothelium, EMBO J, 5, 3179, 10.1002/j.1460-2075.1986.tb04627.x

Thomas, 1993, Tissue factor contributes to microvascular defects following cerebral ischemia, Stroke, 24, 847, 10.1161/01.STR.24.6.847

Okada, 1994, P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion, Stroke, 25, 202, 10.1161/01.STR.25.1.202

Haring, 1996, E-selectin appears in non-ischemic tissue during experimental focal cerebral ischemia, Stroke, 27, 1386, 10.1161/01.STR.27.8.1386

Garcia, 1994, Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat), Am J Pathol, 144, 188

Sirén, 1992, Release of proinflammatory and prothrombotic mediators in the brain and peripheral circulation in spontaneously hypertensive and normotensive Wistar-Kyoto rats, Stroke, 23, 1643, 10.1161/01.STR.23.11.1643

Dawson, 1999, Cerebral hemodynamics and ischemic tolerance, J Cereb Blood Flow Metab, 19, 616, 10.1097/00004647-199906000-00004

Symon, 1987, Pathological regulation in cerebral ischemia, 413

Lenzi, 1982, Cerebral oxygen metabolism and blood flow in human cerebral ischemic infarction, J Cereb Blood Flow Metab, 2, 321, 10.1038/jcbfm.1982.33

Weiss, 1982, Quantitative regional determinatin of morphometric indices of the total and perfused capillary network in the rat brain, Circ Res, 51, 494, 10.1161/01.RES.51.4.494

Symon, 1970, Regional vascular reactivity in the middle cerebral arterial distribution, J Neurosurg, 33, 532, 10.3171/jns.1970.33.5.0532

Moncada, 1988, Endothelium-derived relaxing factor, Biochem Pharmacol, 37, 2495, 10.1016/0006-2952(88)90236-5

Huang, 1996, Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine, J Cereb Blood Flow Metab, 16, 981, 10.1097/00004647-199609000-00023

Huang, 1994, Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase, Science, 265, 1883, 10.1126/science.7522345

Tagaya, 1997, DNA scission following focal brain ischemia, Stroke, 28, 1245, 10.1161/01.STR.28.6.1245

Abumiya, 1999, Activated microvessels express vascular endothelial growth factor and integrin αvβ3 during focal cerebral ischemia, J Cereb Blood Flow Metab, 19, 1038, 10.1097/00004647-199909000-00012

Okada, 1996, Integrin αVβ3 is expressed in selected microvessels following focal cerebral ischemia, Am J Pathol, 149, 37

del Zoppo, 1991, Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons, Stroke, 22, 1276, 10.1161/01.STR.22.10.1276

Garcia, 1974, Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates, J Neuropathol Exp Neurol, 33, 408, 10.1097/00005072-197407000-00007

Garcia, 1987, Light and electron-microscopic features of brain ischemia, 75

Garcia, 1993, Astrocytic and microvascular responses to the occlusion of a middle cerebral artery (Wistar rat), J Neuropathol Exp Neurol, 52, 288, 10.1097/00005072-199305000-00111

del Zoppo, 1986, Experimental acute thrombotic stroke in baboons, Stroke, 17, 1254, 10.1161/01.STR.17.6.1254

Garcia, 1983, Brain capillaries expand and rupture in areas of ischemia and reperfusion, 169