Advances in research on the active constituents and physiological effects of Ganoderma lucidum
Tóm tắt
The review summarizes the traditional usages, distribution, active constituents, structure, and biological effects of
Từ khóa
Tài liệu tham khảo
Ahmad MF. Ganoderma lucidum: persuasive biologically active constituents and their health endorsement. Biomed Pharmacother. 2018;107:507–19.
Baby S, Johnson AJ, Govindan B. Secondary metabolites from Ganoderma. Phytochemistry. 2015;114:66–101.
Bishop KS, Kao CH, Xu Y, Glucina MP, Paterson RR, Ferguson LR. From 2000years of Ganoderma lucidum to recent developments in nutraceuticals. Phytochemistry. 2015;114:56–65.
Campos Ziegenbein F, Hanssen HP, Konig WA. Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus. Phytochemistry. 2006;67(2):202–11.
Chen TQ, Li KB. Resources, taxonomy, ecological distribution, exploitation and utilization of Ganodermataceae from China. Acta Agric Univ Jiangxiensis. 2004;26(1):89–95.
Chen Y, Lv J, Li K, Xu J, Li M, Zhang W, et al. Sporoderm-broken spores of ganoderma lucidum inhibit the growth of lung cancer: involvement of the Akt/mTOR signaling pathway. Nutr Cancer. 2016;68(7):1151–60.
Chung D-J, Yang M-Y, Li Y-R, Chen W-J, Hung C-Y, Wang C-J. Ganoderma lucidum repress injury of ethanol-induced steatohepatitis via anti-inflammation, anti-oxidation and reducing hepatic lipid in C57BL/6J mice. J Funct Foods. 2017;33:314–22.
Cilerdzic JL, Sofrenic IV, Tesevic VV, Brceski ID, Duletic-Lausevic SN, Vukojevic JB, et al. Neuroprotective potential and chemical profile of alternatively cultivated Ganoderma lucidum basidiocarps. Chem Biodivers. 2018;15(5):e1800036.
Cör D, Knez Ž, Knez HM. Antitumour, antimicrobial, antioxidant and antiacetylcholinesterase effect of Ganoderma Lucidum terpenoids and polysaccharides: a review. Molecules. 2018;23(3):649.
Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, et al. Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. Phytochemistry. 2015;114:38–55.
Gao J, Leung K, Wang Y, Lai C, Li S, Hu L, et al. Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS. J Pharm Biomed Anal. 2007;44(3):807–11.
Hapuarachchi K, Elkhateeb W, Karunarathna S, Cheng C, Bandara A, Kakumyan P, et al. Current status of global Ganoderma cultivation, products, industry and market. MYCOSPHERE. 2018;9(5):1025–52.
Hasnat MA, Pervin M, Cha KM, Kim SK, Lim BO. Anti-inflammatory activity on mice of extract of Ganoderma lucidum grown on rice via modulation of MAPK and NF-kappaB pathways. Phytochemistry. 2015;114:125–36.
Hsu K-D, Chen H-J, Wang C-S, Lum C-C, Wu S-P, Lin S-P, et al. Extract of Ganoderma formosanum mycelium as a highly potent tyrosinase inhibitor. Sci Rep. 2016;6:32854.
Hu F, Yan Y, Wang CW, Liu Y, Wang JJ, Zhou F, et al. Article effect and mechanism of Ganoderma lucidum polysaccharides on human fibroblasts and skin wound healing in mice. Chinese journal of integrative medicine. 2019a;25(3):203–9.
Hu S, Huang J, Pei S, Ouyang Y, Ding Y, Jiang L, et al. Ganoderma lucidum polysaccharide inhibits UVB-induced melanogenesis by antagonizing cAMP/ PKA and ROS/MAPK signaling pathways. J Cell Physiol. 2019b;234(5):7330–40.
Hwang E, Lin P, Ngo HTT, Gao W, Wang YS, Yu HS, et al. Icariin and icaritin recover UVB-induced photoaging by stimulating Nrf2/ARE and reducing AP-1 and NF-ĸB signaling pathways: a comparative study on UVB-irradiated human keratinocytes. Photochem Photobiol Sci. 2018;17(10):1396–408.
Jiang L, Huang J, Lu J, Hu S, Pei S, Ouyang Y, et al. Ganoderma lucidum polysaccharide reduces melanogenesis by inhibiting the paracrine effects of keratinocytes and fibroblasts via IL-6/STAT3/FGF2 pathway. J Cell Physiol. 2019. https://doi.org/10.1002/jcp.28844.
Kao CH, Bishop KS, Xu Y, Han DY, Murray PM, Marlow GJ, et al. Identification of potential anticancer activities of novel Ganoderma lucidum extracts using gene expression and pathway network analysis. Genomics insights. 2016;9:1–16.
Khanna PK, Shivani HK, Gupta S, Chahal KK, editors. Evaluating Ganoderma lucidum strains for the production of bioactive components. Congress of the International Society for Mushroom Science; 2012.
Kim JW, Kim HI, Kim JH, Kwon OC, Son ES, Lee CS, et al. Effects of ganodermanondiol, a new melanogenesis inhibitor from the medicinal mushroom manoderma lucidum. Int J Mol Sci. 2016;17:11.
Kong SZ, Li DD, Luo H, Li WJ, Huang YM, Li JC, et al. Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin. Exp Gerontol. 2018;103:27–34.
Kubota A, Kobayashi M, Sarashina S, Takeno R, Okamoto K, Narumi K, et al. Reishi mushroom Ganoderma lucidum modulates IgA production and alpha-defensin expression in the rat small intestine. J Ethnopharmacol. 2018;214:240–3.
Kumakura K, Hori C, Matsuoka H, Igarashi K, Samejima M. Protein components of water extracts from fruiting bodies of the Reishi mushroom Ganoderma lucidum contribute to the production of functional molecules. J Sci Food Agric. 2019;99(2):529–35.
Lee S, Bae I, Lee E, Min D, Park N, Choi S, et al. 1116 The extract of Ganoderma lucidum inhibits MMP-1 expression through suppression of ERK activation in UVB irradiated dermal fibroblast and skin equivalent model. J Investig Dermatol. 2018;138(5):S190.
Lee YH, Kim JH, Song CH, Jang KJ, Kim CH, Kang JS, et al. Ethanol extract of Ganoderma lucidum augments cellular anti-oxidant defense through activation of Nrf2/HO-1. Journal of pharmacopuncture. 2016;19(1):59–69.
Lin CC, Yu YL, Shih CC, Liu KJ, Ou KL, Hong LZ, et al. A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells. Cancer immunology, immunotherapy: CII. 2011;60(7):1019–27.
Liu JQ, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, et al. Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora. Food Chem. 2018;263:155–62.
Liu Y, Zhang J, Tang Q, Yang Y, Guo Q, Wang Q, et al. Physicochemical characterization of a high molecular weight bioactive beta-d-glucan from the fruiting bodies of Ganoderma lucidum. Carbohydr Polym. 2014;101:968–74.
Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, et al. Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.). Int Immunopharmacol. 2015;25(1):112–20.
Montalbano G. Evaluation of the antimicrobial, anti-inflammatory, regenerative and wound healing properties of the bracket fungus ganoderma lucidum. Queensland University of Technology; 2018.
Ren ZL, Wang CD, Wang T, Ding H, Zhou M, Yang N, et al. Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis. Acta Pharmacol Sin. 2019;40(4):441–50.
Sa-Ard P, Sarnthima R, Khammuang S, Kanchanarach W. Antioxidant, antibacterial and DNA protective activities of protein extracts from Ganoderma lucidum. J Food Sci Technol. 2015;52(5):2966–73.
Sarnthima R, Khammaung S, Sa-Ard P. Culture broth of Ganoderma lucidum exhibited antioxidant, antibacterial and alpha-amylase inhibitory activities. J Food Sci Technol. 2017;54(11):3724–30.
Shen C, Shen B, Shen G, Li J, Zhang FC, Xu P, et al. Therapeutic effects of nanogel containing triterpenoids isolated from Ganoderma lucidum (GLT) using therapeutic ultrasound (TUS) for frostbite in rats. Drug delivery. 2016;23(8):2643–50.
Siwulski M, Sobieralski K, Golak-Siwulska I, Sokół S, Sękara A. Ganoderma lucidum (Curt.: Fr.) Karst. – health-promoting properties. A review. Herba Polonica. 2015;61(3):105–18.
Smina TP, Nitha B, Devasagayam TP, Janardhanan KK. Ganoderma lucidum total triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas in experimental animals. Mutation Research/genetic Toxicology & Environmental Mutagenesis. 2017;813:45–51.
Sone Y, Okuda R, Wada N, Kishida E, Misaki A. Structures and antitumor activities of the polysaccharides isolated from fruiting body and the growing culture of mycelium of Ganoderma lucidum. Agric Biol Chem. 1985;49(9):2641-53.
Tian Y, Yang T, Yu S, Liu C, He M, Hu C. Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med. 2018;22(12):6327–37.
Wang C, Shi S, Chen Q, Lin S, Wang R, Wang S, et al. Antitumor and immunomodulatory activities of Ganoderma lucidum polysaccharides in glioma-bearing rats. Integrative cancer therapies. 2018;17(3):674–83.
Wang XC, Xi RJ, Li Y, Wang DM, Yao YJ. The species identity of the widely cultivated Ganoderma, 'G. lucidum' (Ling-zhi), in China. PLoS One. 2012;7(7):e40857.
Wei B, Zhang R, Zhai J, Zhu J, Yang F, Yue D, et al. Suppression of Th17 cell response in the alleviation of dextran sulfate sodium-induced colitis by Ganoderma lucidum polysaccharides. J Immunol Res. 2018;2018:2906494.
Wu JG, Kan YJ, Wu YB, Yi J, Chen TQ, Wu JZ. Hepatoprotective effect of ganoderma triterpenoids against oxidative damage induced by tert-butyl hydroperoxide in human hepatic HepG2 cells. Pharm Biol. 2016;54(5):919–29.
Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, et al. A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp. Molecules. 2014;19(11):17478–535.
Xiao C, Wu Q, Zhang J, Xie Y, Cai W, Tan J. Antidiabetic activity of Ganoderma lucidum polysaccharides F31 down-regulated hepatic glucose regulatory enzymes in diabetic mice. J Ethnopharmacol. 2017;196:47–57.
Yang Z, Wu F, He Y, Zhang Q, Zhang Y, Zhou G, et al. A novel PTP1B inhibitor extracted from Ganoderma lucidum ameliorates insulin resistance by regulating IRS1-GLUT4 cascades in the insulin signaling pathway. Food Funct. 2018;9(1):397–406.
Yang Z, Zhang Z, Zhao J, He Y, Yang H, Zhou P. Modulation of energy metabolism and mitochondrial biogenesis by a novel proteoglycan from Ganoderma lucidum. RSC Adv. 2019;9(5):2591–8.
Yu HZ, Liu YF, Zhou S, Zhang Z, Wang C, Tang QJ, et al. Difference of chemical components in fruiting body, mycelium and spore powder of Ganoderma lingzhi. Journal of Food Science & Biotechnology. 2016;35(08):823–7.
Zeng Q, Zhou F, Lei L, Chen J, Lu J, Zhou J, et al. Ganoderma lucidum polysaccharides protect fibroblasts against UVB-induced photoaging. Mol Med Rep. 2017;15(1):111–6.
Zhang H, Jiang H, Zhang X, Yan J. Amino acids from Ganoderma lucidum: extraction optimization, composition analysis, hypoglycemic and antioxidant activities. Curr Pharm Anal. 2018a;14(6):562–70.
Zhang K, Liu Y, Zhao X, Tang Q, Dernedde J, Zhang J, et al. Anti-inflammatory properties of GLPss58, a sulfated polysaccharide from Ganoderma lucidum. Int J Biol Macromol. 2018b;107:486–93.
Zhang L, Ding Z, Xu P, Wang Y, Gu Z, Qian Z, et al. Methyl lucidenate F isolated from the ethanol-soluble-acidic components of Ganoderma lucidum is a novel tyrosinase inhibitor. Biotechnol Bioprocess Eng. 2011;16(3):457–61.
Zhao C, Fan J, Liu Y, Guo W, Cao H, Xiao J, et al. Hepatoprotective activity of Ganoderma lucidum triterpenoids in alcohol-induced liver injury in mice, an iTRAQ-based proteomic analysis. Food Chem. 2019;271:148–56.
Zheng L, Wong YS, Shao M, Huang S, Wang F, Chen J. Apoptosis induced by 9,11dehydroergosterol peroxide from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl1 dependent. Mol Med Rep. 2018;18(1):938–44.