Adolescent Substance Use in the Multimodal Treatment Study of Attention-Deficit/Hyperactivity Disorder (ADHD) (MTA) as a Function of Childhood ADHD, Random Assignment to Childhood Treatments, and Subsequent Medication

Brooke S. G. Molina1, Stephen P. Hinshaw, L. Eugene Arnold, James M. Swanson, William E. Pelham, Lily Hechtman, Betsy Hoza, Jeffery N. Epstein, Timothy Wigal, Howard Abikoff, Laurence L. Greenhill, Peter S. Jensen, Karen C. Wells, Benedetto Vitiello, Robert D. Gibbons, Andrea L. Howard, Patricia R. Houck, Kwan Hur, Bo Lü, Sue M. Marcus
1Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]

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Charach, 2011, Childhood attention-deficit/hyperactivity disorder and future substance use disorders: comparative meta-analyses, J Am Acad Child Adolesc Psychiatry, 50, 9, 10.1016/j.jaac.2010.09.019

Lee, 2011, Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review, Clin Psychol Rev, 31, 328, 10.1016/j.cpr.2011.01.006

Derefinko, 2013, ADHD and substance use

Molina, 2011, Delinquency and substance use in ADHD: adolescent and young adult outcomes in developmental context, Vol. 2

Pelham, 2008, Evidence-based psychosocial treatment for attention deficit/hyperactivity disorder: an update, J Clin Child Adolesc Psychol, 37, 185, 10.1080/15374410701818681

Swanson, 2011, Contrast of medical and nonmedical use of stimulant drugs, basis for the distinction, and risk of addiction: comment on Smith and Farah (2011), Psychol Bull, 137, 742, 10.1037/a0024898

Arnold, 2000, Methylphenidate vs. amphetamine: comparative review, J Atten Disord, 3, 200, 10.1177/108705470000300403

Faraone, 2010, Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis, Eur Child Adolesc Psychiatry, 19, 353, 10.1007/s00787-009-0054-3

Barkley, 2008

Chang, 2012, The effects of childhood ADHD symptoms on early-onset substance use: a Swedish twin study, J Abnorm Child Psychol, 40, 425, 10.1007/s10802-011-9575-6

Knop, 2009, Childhood ADHD and conduct disorder as independent predictors of male alcohol dependence at age 40, J Stud Alcohol Drugs, 70, 169, 10.15288/jsad.2009.70.169

Molina, 2012, Childhood ADHD and growth in adolescent alcohol use: the roles of functional impairments, ADHD symptom persistence, and parental knowledge, J Abnorm Psychol, 121, 922, 10.1037/a0028260

Lambert, 2006, Subjective responses to initial experience with cocaine: an exploration of the incentive–sensitization theory of drug abuse, Addiction, 101, 713, 10.1111/j.1360-0443.2006.01408.x

Volkow, 2008, Does childhood treatment of ADHD with stimulant medication affect substance abuse in adulthood?, Am J Psychiatry, 165, 553, 10.1176/appi.ajp.2008.08020237

Valvassori, 2007, Sensitization and cross-sensitization after chronic treatment with methylphenidate in adolescent Wistar rats, Behav Pharmacol, 18, 205, 10.1097/FBP.0b013e328153daf5

Wilens, 2003, Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature, Pediatrics, 111, 179, 10.1542/peds.111.1.179

Biederman, 1999, Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder, Pediatrics, 104, e20, 10.1542/peds.104.2.e20

Loney, 2002, Medicated vs. unmedicated ADHD children: adult involvement with legal and illegal drugs

Mannuzza, 2008, Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood, Am J Psychiatry, 165, 604, 10.1176/appi.ajp.2008.07091465

Wilens, 2008, Effect of prior stimulant treatment for attention-deficit/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescents, Arch Pediatr Adolesc Med, 162, 916, 10.1001/archpedi.162.10.916

Lambert, 2005, The contribution of childhood ADHD, conduct problems, and stimulant treatment to adolescent and adult tobacco and psychoactive substance abuse, Ethic Hum Psychol Psychiatry, 7, 197, 10.1891/1559-4343.7.3.197

Lambert, 1998, Prospective study of tobacco smoking and substance dependencies among samples of ADHD and non-ADHD participants, J Learn Disabil, 31, 533, 10.1177/002221949803100603

Biederman, 2008, Stimulant therapy and risk for subsequent substance use disorders in male adults with ADHD: a naturalistic controlled 10-year follow-up study, Am J Psychiatry, 165, 597, 10.1176/appi.ajp.2007.07091486

Molina, 2007, Delinquent behavior and emerging substance use in the MTA at 36-months: prevalence, course, and treatment effects, J Am Acad Child Adolesc Psychiatry, 46, 1027, 10.1097/chi.0b013e3180686d96

Barkley, 2003, Does the treatment of attention-deficit/hyperactivity disorder with stimulants contribute to drug use/abuse? A 13-year prospective study, Pediatrics, 111, 97, 10.1542/peds.111.1.97

Katusic, 2005, Psychostimulant treatment and risk for substance abuse among young adults with a history of attention-deficit/hyperactivity disorder: a population-based, birth cohort study, J Child Adolesc Psychopharmacol, 15, 764, 10.1089/cap.2005.15.764

Harty, 2011, The impact of conduct disorder and stimulant medication on later substance use in an ethnically diverse sample of individuals with attention-deficit/hyperactivity disorder in childhood, J Child Adolesc Psychopharmacol, 21, 331, 10.1089/cap.2010.0074

Winters, 2011, A prospective examination of the association of stimulant medication history and drug use outcomes among community samples of ADHD youths, J Child Adolescent Subst Abuse, 20, 314, 10.1080/1067828X.2011.598834

Substance Abuse and Mental Health Services Administration. Results from the 2008 National Survey on Drug Use and Health: National Findings. NSDUH Series H-36, HHS Publication No. (SMA) 09-4434. Rockville, MD: Office of Applied Studies; 2009.

Swanson, 2008, Evidence, interpretation, and qualification from multiple reports of long-term outcomes in the Multimodal Treatment Study of Children with ADHD (MTA) Part I: Executive Summary, J Atten Disord, 12, 4, 10.1177/1087054708319345

Swanson, 2008, Evidence, interpretation, and qualification from multiple reports of long-term outcomes in the Multimodal Treatment Study of Children with ADHD (MTA). Part II: Supporting details, J Atten Disord, 12, 15, 10.1177/1087054708319525

Swendsen, 2012, Use and abuse of alcohol and illicit drugs in US adolescents, Arch Gen Psychiatry, 69, 390, 10.1001/archgenpsychiatry.2011.1503

Jensen, 2007, 3-Year follow-up of the NIMH MTA Study, J Am Acad Child Adolesc Psychiatry, 46, 988, 10.1097/CHI.0b013e3180686d48

Lu, 2001, Matching with doses in an observational study of a media campaign against drug abuse, J Am Stat Assoc, 96, 1245, 10.1198/016214501753381896

Swanson, 2007, Secondary evaluations of MTA 36-month outcomes: propensity score and growth mixture model analyses, J Am Acad Child Adolesc Psychiatry, 46, 1002, 10.1097/CHI.0b013e3180686d63

Rezvani, 2001, Cognitive effects of nicotine, Biol Psychiatry, 49, 258, 10.1016/S0006-3223(00)01094-5

Babinski, 2011, Late adolescent and young adult outcomes of girls diagnosed with ADHD in childhood: an exploratory investigation, J Atten Disord, 15, 204, 10.1177/1087054710361586

Biederman, 2006, Psychopathology in females with attention-deficit/hyperactivity disorder: a controlled five-year prospective study, Biol Psychol, 60, 1098, 10.1016/j.biopsych.2006.02.031

Hinshaw, 2006, Prospective follow-up of girls with attention-deficit/hyperactivity disorder into adolescence: evidence for continuing cross-domain impairment, J Consult Clin Psychol, 74, 489, 10.1037/0022-006X.74.3.489

Hinshaw, 2012, Prospective follow-up of girls with attention-deficit hyperactivity disorder into early adulthood: continuing impairment includes elevated risk for suicide attempts and self-injury, J Consult Clinical Psychol, 80, 1041, 10.1037/a0029451

Arnold, 1997, NIMH collaborative multimodal treatment study of children with ADHD (MTA): design, methodology, and protocol evolution, J Atten Disord, 2, 141, 10.1177/108705479700200301

Greenhill, 1996, Medication treatment strategies in the MTA: relevance to clinicians and researchers, J Am Acad Child Adoelsc Psychiatry, 35, 1304, 10.1097/00004583-199610000-00017

Hinshaw, 1997, Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial, J Atten Disord, 1, 217, 10.1177/108705479700100403

MTA Cooperative Group, 1999, A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder, Arch Gen Psychiatry, 56, 1073, 10.1001/archpsyc.56.12.1073

MTA Cooperative Group, 1999, Moderators and mediators of treatment response for children with attention-deficit/hyperactivity disorder, Arch Gen Psychiatry, 56, 1088, 10.1001/archpsyc.56.12.1088

Wells, 2000, Psychosocial treatment strategies in the MTA study: rationale, methods, and critical issues in design and implementation, J Abnorm Child Psychol, 28, 483, 10.1023/A:1005174913412

Molina, 2009, The MTA at 8 years: prospective follow-up of children treated for combined type ADHD in a multisite study, J Am Acad Child Adolesc Psychiatry, 48, 484, 10.1097/CHI.0b013e31819c23d0

Shaffer, 2000, NIMH diagnostic interview schedule for children version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses, J Am Acad Child Adolesc Psychiatry, 39, 28, 10.1097/00004583-200001000-00014

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed., DSM-IV, Washington, DC; 1994.

Molina, 2003, Childhood predictors of adolescent substance use in a longitudinal study of children with ADHD, J Abnorm Psychol, 112, 497, 10.1037/0021-843X.112.3.497

Donovan, 1994

Jessor, 1989

National Household Survey on Drug Abuse (NHSDA). National Institute on Drug Abuse, U.S. Dept of Health and Human Services; 1992. OMB No: 0930-0110.

Winters, 2005, Assessment issues in adolescent drug abuse treatment research, 407, 10.1007/0-306-48626-1_19

Hedeker, 2000, Analysis of longitudinal substance use outcomes using ordinal random-effects regression models, Addiction, 95, S381, 10.1046/j.1360-0443.95.11s3.7.x

Robins, 2000

Hoagwood, 2004, Reliability of the Services for Children and Adolescents Parent Interview (SCAPI), J Am Acad Child Adolesc Psychiatry, 43, 1345, 10.1097/01.chi.0000139558.54948.1f

Jensen, 2004, The Services for Children and Adolescents Parent Interview (SCAPI): development and performance characteristics, J Am Acad Child Adolesc Psychiatry, 43, 1334, 10.1097/01.chi.0000139557.16830.4e

Hedeker, 2006

Swanson, 2001, Clinical relevance of the primary findings of the MTA: success rates based on severity of ADHD and ODD symptoms at the end of treatment, J Am Acad Child Adolesc Psychiatry, 40, 168, 10.1097/00004583-200102000-00011

Biederman, 1997, Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective follow-up study, J Am Acad Child Adolesc Psychiatry, 36, 21, 10.1097/00004583-199701000-00013

Chassin, 2002, Binge drinking trajectories from adolescence to emerging adulthood in a high-risk sample: predictors and substance use outcomes, J Clin Child Psychol, 70, 67

Grant, 1997, Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: results from the National Longitudinal Epidemiologic Survey, J Subst Abuse, 9, 103, 10.1016/S0899-3289(97)90009-2

Barkley, 1990, The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study, J Am Acad Child Adolesc Psychiatry, 29, 546, 10.1097/00004583-199007000-00007

Hartsough, 1987, Pattern and progression of drug use among hyperactives and controls: a prospective short-term longitudinal study, J Child Psychol Psychiatry, 28, 543, 10.1111/j.1469-7610.1987.tb00222.x

Substance Abuse and Mental Health Services Administration, 2011

Brook, 2008, The association between earlier marijuana use and subsequent academic achievement and health problems: a longitudinal study, Am J Addict, 17, 155, 10.1080/10550490701860930

Crean, 2011, An evidence-based review of acute and long-term effects of cannabis use on executive cognitive functions, J Addict Med, 5, 1, 10.1097/ADM.0b013e31820c23fa

Grant, 2003, Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study, J Int Neuropsychol Soc, 9, 679, 10.1017/S1355617703950016

Hanson, 2011, Impact of adolescent alcohol and drug use on neuropsychological functioning in young adulthood: 10-year outcomes, J Child Adolesc Subst Abuse, 20, 135, 10.1080/1067828X.2011.555272

Pope, 2003, Early-onset cannabis use and cognitive deficits: what is the nature of the association?, Drug Alcohol Depend, 69, 303, 10.1016/S0376-8716(02)00334-4

Meier MH, Caspi A, Harrington H, et al. Persistent cannabis users show neuropsychological decline from childhood to midlife. [published online ahead of print August 27, 2012]. Proc Natl Acad Sci USA. E2657-E2664.

Centers for Disease Control and Prevention. Youth Risk Behavior Surveillance— United States, 2009. MMWR CDC Surveill Summ. 2010; 59(SS-5). Accessed March 27, 2012.

Milberger, 1997, ADHD is associated with early initiation of cigarette smoking in children and adolescents, J Am Acad Child Adolesc Psychiatry, 36, 37, 10.1097/00004583-199701000-00015

Centers for Disease Control and Prevention. Vital Signs: Current Cigarette Smoking among Adults Aged>18 Years—United States, 2005-2010. MMWR CDC Surveill Summ. 2011;60:1207-1212. Accessed January 24, 2012.

Chen, 1998, Age of smoking initiation: Implications for quitting, Health Rep, 9, 39

Riggs, 2007, Adolescent to emerging adulthood smoking trajectories: when do smoking trajectories diverge, and do they predict early adulthood nicotine dependence?, Nicotine Tob Res, 9, 1147, 10.1080/14622200701648359

Chen, 2002, Prior cigarette smoking initiation predicting current alcohol use: evidence for a gateway drug effect among California adolescents from eleven ethnic groups, Addict Behav, 27, 799, 10.1016/S0306-4603(01)00211-8

Petraitis, 1995, Reviewing theories of adolescent substance use: organizing pieces in the puzzle, Psychol Bull, 117, 67, 10.1037/0033-2909.117.1.67

Iacono, 2008, Behavioral disinhibition and the development of early-onset addiction: common and specific influences, Annu Rev Clin Psychol, 4, 325, 10.1146/annurev.clinpsy.4.022007.141157

Zucker, 2008, Early developmental processes and the continuity of risk for underage drinking and problem drinking, Pediatrics, 121, S252, 10.1542/peds.2007-2243B

Brook, 2010, Association between attention-deficit/hyperactivity disorder in adolescence and substance use disorders in adulthood, Arch Pediatr Adolesc Med, 164, 930, 10.1001/archpediatrics.2010.180

Gittelman, 1985, Hyperactive boys almost grown up: I. Psychiatric status, Arch Gen Psychiatry, 42, 937, 10.1001/archpsyc.1985.01790330017002

Waldron, 2008, Evidence-based psychosocial treatments for adolescent substance abuse, J Clin Child Adolesc Psychol, 37, 238, 10.1080/15374410701820133

Spas, 2012, All might have won, but not all have the prize: optimal treatment for substance abuse among adolescents with conduct problems, Subst Abuse, 6, 1

Volkow, 2012, Methylphenidate-elicited dopamine increases in ventral striatum are associated with long-term symptom improvement in adults with attention deficit hyperactivity disorder, J Neurosci, 32, 841, 10.1523/JNEUROSCI.4461-11.2012

Wang, 2009, Chronic treatment with methylphenidate increases dopamine transporter density in patients with attention deficit hyperactive disorder, J Nucl Med, 50, 1283

Castellanos, 2002, Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder, JAMA, 288, 1740, 10.1001/jama.288.14.1740

Brown, 2001, Prevalence and assessment of attention-deficit/hyperactivity disorder in primary care settings, Pediatrics, 107, e43, 10.1542/peds.107.3.e43