Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial

The Lancet - Tập 386 Số 9992 - Trang 433-443 - 2015
Michael Gnant1,2, Georg Pfeiler1,3, Peter Dubsky1,2, Michael Hubalek4, Richard Greil5,6, Raimund Jakesz1,2, Viktor Wette7, Marija Balić8, Ferdinand Haslbauer9, Elisabeth Melbinger10, Vesna Bjelic‐Radisic11, Silvia Artner-Matuschek12, Florian Fitzal13,1,2, Christian Marth4, P. Sevelda14, Brigitte Mlineritsch5, Günther Steger15, D. Manfreda16, Ruth Exner1,2, Daniel Egle4, Jonas Bergh17, Franz Kainberger18, Susan Talbot19, Douglas Warner20, Christian Fesl21, Christian F. Singer1,3
1Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
2Department of Surgery, Medical University of Vienna, Vienna, Austria
3Department of Gynecology and Obstetrics, Medical University of Vienna, Vienna, Austria
4Department of Gynecology, Medical University Innsbruck, Innsbruck, Austria
5Department of Internal Medicine III, Paracelsus Medical University Salzburg, Salzburg, Austria
6Salzburg Cancer Research Institute, Salzburg, Austria
7Doctor's Office Wette, Breast Center, St Veit an der Glan, Austria
8Department of Oncology, Medical University of Graz, Graz, Austria
9Department of Internal Medicine, Hospital Vöcklabruck, Vöcklabruck, Austria
10Department of Surgery, Hospital Wolfsberg, Wolfsberg, Austria
11Department of Gynecology, Medical University of Graz, Graz, Austria
12Department of Surgery, Breast Center Hospital Hanusch Vienna, Vienna, Austria
13Breast Health Center, Hospital of Sisters of Mercy Linz, Linz, Austria
14Department of Gynecology, Hospital Hietzing, Vienna, Austria
15Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria
16Doctor's Office Manfreda, Klagenfurt, Austria
17Department of Oncology/Radiumhemmet, Karolinska Oncology, Karolinska Institutet and University Hospital, Stockholm, Sweden
18Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
19Amgen Ltd., Uxbridge, UK
20Amgen Inc., Thousand Oaks, CA USA
21Department of Statistics, Austrian Breast & Colorectal Cancer Study Group, Vienna, Austria

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