Adipocytes harbor a glucosylceramide biosynthesis pathway involved in iNKT cell activation

Maryam Rakhshandehroo1, Robert J. van Eijkeren1, Tanit L. Gabriel2, Colin de Haar3, Sanne M.W. Gijzel1, Nicole Hamers1, Maria J. Ferraz4, Johannes M.F.G. Aerts4, Henk S. Schipper3,5, Marco van Eijk4, Marianne Boes3,6, Eric Kalkhoven1
1Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands
2Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
3Laboratory for Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands
4Leiden Institute of Chemistry, Department of Biochemistry, Leiden University, Leiden, the Netherlands
5Department of Pediatric Cardiology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, The Netherlands
6Department of Paediatric Immunology, University Medical Center Utrecht, Utrecht, the Netherlands

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