Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling

Molecular Metabolism - Tập 42 - Trang 101086 - 2020
Hyun Cheol Roh1,2,3, Manju Kumari1, Solaema Taleb3, Danielle Tenen1,2, Christopher Jacobs1,2, Anna Lyubetskaya1,2, Linus T.-Y. Tsai1,2, Evan D. Rosen1,2
1Division of Endocrinology, Diabetes and Obesity, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA
2Broad Institute, Cambridge, MA 02142, USA
3Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA

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