Add-on topiramate in the treatment of refractory partial-onset epilepsy: Clinical experience of outpatient epilepsy clinics from 11 general hospitals

Marson, 1996, New antiepileptic drugs: a systematic review of their efficacy and tolerability, Br Med J, 313, 1169, 10.1136/bmj.313.7066.1169 Elferink, 1997, Analysis based on number needed to treat shows differences between drugs studied, Br Med J, 314, 603 Sharief, 1996, Double-blind, placebo-controlled study of topiramate in patients with refractory partial epilepsy, Epilepsy Res, 25, 217, 10.1016/S0920-1211(96)00029-0 Sander, 1997, Practical aspects of the use of topiramate in patients with epilepsy, Epilepsia, 38, 556, 10.1111/j.1528-1157.1997.tb04521.x Sachdeo, 1997, Topiramate monotherapy for partial onset seizures, Epilepsia, 38, 294, 10.1111/j.1528-1157.1997.tb01120.x Gilliam, 2003, A dose-comparison trial of topiramate as monotherapy in recently diagnosed partial epilepsy, Neurology, 60, 196, 10.1212/01.WNL.0000048200.12663.BC Privitera, 2003, Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy, Acta Neurol Scand, 107, 165, 10.1034/j.1600-0404.2003.00093.x Faught, 1996, Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400- and 600-mg daily dosages, Neurology, 46, 1684, 10.1212/WNL.46.6.1684 Ben Menachem, 1996, Double-blind, placebo-controlled trial of topiramate as add-on therapy in patients with refractory partial seizures, Epilepsia, 37, 539, 10.1111/j.1528-1157.1996.tb00606.x Tassinari, 1996, Double-blind, placebo-controlled trial of topiramate (600mg daily) for the treatment of refractory partial epilepsy, Epilepsia, 37, 763, 10.1111/j.1528-1157.1996.tb00649.x Privitera, 1996, Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, and 1000-mg daily dosages, Neurology, 46, 1678, 10.1212/WNL.46.6.1678 Rosenfeld, 1996, Placebo controlled trial of topiramate as adjunctive therapy to carbamazepine or phenytoin for partial-onset epilepsy, Epilepsia, 37, 153 International League Against Epilepsy. International classification of epileptic seizures. Epilepsia 1981;22:489–501. PRI. Topamax (topiramate) Epilepsy Product Monograph; 2000. Peeters, 2003, A pooled analysis of adjunctive topiramate in refractory partial epilepsy, Acta Neurol Scand, 108, 9, 10.1034/j.1600-0404.2003.00113.x Guberman, 2002, Low-dose topiramate in adults with treatment-resistant partial-onset seizures, Acta Neurol Scand, 106, 183, 10.1034/j.1600-0404.2002.02071.x Reife, 2000, Topiramate as add-on therapy: pooled analysis of randomized controlled trials in adults, Epilepsia, 41, S66, 10.1111/j.1528-1157.2000.tb02175.x Grant, 1991, Vigabatrin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and motor control, Drugs, 41, 889, 10.2165/00003495-199141060-00007 Sander, 1990, The efficacy and long-term tolerability of lamotrigine in the treatment of severe epilepsy, Epilepsy Res, 7, 226, 10.1016/0920-1211(90)90019-R UK Gabapentin Group. Gabapentin in partial epilepsy. Lancet 1990;335:114–7.