Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

Cell Metabolism - Tập 30 - Trang 754-767.e9 - 2019
José M. Bravo-San Pedro1,2,3, Valentina Sica1,2,3, Isabelle Martins1,2,3, Jonathan Pol1,2,3, Friedemann Loos1,2,3, Maria Chiara Maiuri1,2,3, Sylvère Durand1,2,3, Noélie Bossut1,2,3, Fanny Aprahamian1,2,3, Gerasimos Anagnostopoulos1,2,3,4, Mireia Niso-Santano5, Fernando Aranda6, Ignacio Ramírez-Pardo7, Justine Lallement8, Jessica Denom8, Erwan Boedec9,10,11, Philip Gorwood12,13, Nicolas Ramoz13, Karine Clément14, Veronique Pelloux14
1INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France
2Team “Metabolism, Cancer & Immunity”, Équipe 11 labellisée par la Ligue contre le Cancer, Paris, France
3Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France
4Faculté de Médecine, Université de Paris Saclay, Kremlin Bicêtre, France
5Biomedical Research Networking Center on Neurodegenerative Diseases (CIBERNED), Department of Biochemistry and Molecular Biology and Genetics, University of Extremadura, Faculty of Nursing and Occupational Therapy, Cáceres, Spain
6Group of Immune receptors of the Innate and Adaptive System, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
7Department of Cellular and Molecular Biology, Centro de Investigaciones Biológicas (CSIC), Madrid, Spain
8Université of Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, Paris, France
9INSERM U1149, Center of Research on Inflammation, Paris, France
10Paris-Diderot University, Sorbonne Paris Cité, Paris, France
11National French Center of Scientific Research (CNRS), ERL 8252, Paris, France
12Clinique des Maladies Mentales et de l'Encéphale (CMME), Hôpital Sainte-Anne, Université of Paris, Paris, France
13INSERM U894, Centre de Psychiatrie et Neurosciences (CPN), Université of Paris, Paris, France
14Sorbonne Université, Inserm, NutriOMics team, Pitié-Salpêtrière Hospital, Paris, France

Tài liệu tham khảo

Amaravadi, 2016, Recent insights into the function of autophagy in cancer, Genes Dev., 30, 1913, 10.1101/gad.287524.116 Barmack, 2004, Activity-dependent expression of acyl-coenzyme A-binding protein in retinal Muller glial cells evoked by optokinetic stimulation, J. Neurosci., 24, 1023, 10.1523/JNEUROSCI.3936-03.2004 Bek, 2015, Compromised epidermal barrier stimulates harderian gland activity and hypertrophy in ACBP-/- mice, J. Lipid Res., 56, 1738, 10.1194/jlr.M060780 Bhuiyan, 1995, Effects of high-fat diet and fasting on levels of acyl-coenzyme A binding protein in liver, kidney, and heart of rat, Metabolism, 44, 1185, 10.1016/0026-0495(95)90013-6 Bormann, 1991, Electrophysiological characterization of diazepam binding inhibitor (DBI) on GABAA receptors, Neuropharmacology, 30, 1387, 10.1016/S0028-3908(11)80006-7 Boudoures, 2017, Obesity-exposed oocytes accumulate and transmit damaged mitochondria due to an inability to activate mitophagy, Dev. Biol., 426, 126, 10.1016/j.ydbio.2017.04.005 Bravo-San Pedro, 2017, High-throughput quantification of GFP-LC3+ dots by automated fluorescence microscopy, Methods Enzymol, 587, 71, 10.1016/bs.mie.2016.10.022 Christian, 2013, Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor, Neuron, 78, 1063, 10.1016/j.neuron.2013.04.026 Conti, 2013, Reduced fasting plasma levels of diazepam-binding inhibitor in adolescents with anorexia nervosa, Int. J. Eat. Disord., 46, 626, 10.1002/eat.22129 Cotillard, 2013, Dietary intervention impact on gut microbial gene richness, Nature, 500, 585, 10.1038/nature12480 Dupont, 2011, Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta, EMBO J., 30, 4701, 10.1038/emboj.2011.398 Duran, 2010, Unconventional secretion of Acb1 is mediated by autophagosomes, J. Cell Biol., 188, 527, 10.1083/jcb.200911154 Esteban-Martínez, 2015, Autophagic flux determination in vivo and ex vivo, Methods, 75, 79, 10.1016/j.ymeth.2015.01.008 Farooqi, 2001, Partial leptin deficiency and human adiposity, Nature, 414, 34, 10.1038/35102112 Fernández, 2017, Autophagy couteracts weight gain, lipotoxicity and pancreatic beta-cell death upon hypercaloric pro-diabetic regimens, Cell Death Dis., 8, e2970, 10.1038/cddis.2017.373 Galluzzi, 2014, Metabolic control of autophagy, Cell, 159, 1263, 10.1016/j.cell.2014.11.006 Guillebaud, 2017, Glial endozepines inhibit feeding-related autonomic functions by acting at the brainstem level, Front. Neurosci., 11, 308, 10.3389/fnins.2017.00308 Gulati, 2007, Nutrient sensing in the mTOR/S6K1 signalling pathway, Biochem. Soc. Trans., 35, 236, 10.1042/BST0350236 Hansen, 1991, Induction of acyl-CoA-binding protein and its mRNA in 3T3-L1 cells by insulin during preadipocyte-to-adipocyte differentiation, Biochem. J., 277, 341, 10.1042/bj2770341 He, 2013, Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism, Cell, 154, 1085, 10.1016/j.cell.2013.07.035 Henning, 2017, Proteostasis in cardiac health and disease, Nat. Rev. Cardiol., 14, 637, 10.1038/nrcardio.2017.89 Inui, 2001, Ghrelin: an orexigenic and somatotrophic signal from the stomach, Nat. Rev. Neurosci., 2, 551, 10.1038/35086018 Izzo, 2017, Metabolic interactions between cysteamine and epigallocatechin gallate, Cell Cycle, 16, 271, 10.1080/15384101.2016.1249550 Kimura, 2017, Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy, EMBO J., 36, 42, 10.15252/embj.201695081 Kinseth, 2007, The Golgi-associated protein GRASP is required for unconventional protein secretion during development, Cell, 130, 524, 10.1016/j.cell.2007.06.029 Klionsky, 2016, Guidelines for the use and interpretation of assays for monitoring autophagy, [Third edition], Autophagy, 12, 1, 10.1080/15548627.2015.1100356 Koga, 2010, Altered lipid content inhibits autophagic vesicular fusion, FASEB J., 24, 3052, 10.1096/fj.09-144519 Landrock, 2010, Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice, Lipids, 45, 567, 10.1007/s11745-010-3437-9 Lanfray, 2013, Gliotransmission and brain glucose sensing: critical role of endozepines, Diabetes, 62, 801, 10.2337/db11-0785 Lassailly, 2015, Bariatric surgery reduces features of nonalcoholic steatohepatitis in morbidly obese patients, Gastroenterology, 149, 379, 10.1053/j.gastro.2015.04.014 Levine, 2019, Biological functions of autophagy genes: a disease perspective, Cell, 176, 11, 10.1016/j.cell.2018.09.048 López-Otín, 2016, Metabolic control of longevity, Cell, 166, 802, 10.1016/j.cell.2016.07.031 Manjithaya, 2010, Unconventional secretion of pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation, J. Cell Biol., 188, 537, 10.1083/jcb.200911149 Mariño, 2010, Autophagy is essential for mouse sense of balance, J. Clin. Invest., 120, 2331, 10.1172/JCI42601 Mariño, 2014, Regulation of autophagy by cytosolic acetyl-coenzyme A, Mol. Cell, 53, 710, 10.1016/j.molcel.2014.01.016 Menzies, 2017, Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities, Neuron, 93, 1015, 10.1016/j.neuron.2017.01.022 Mizunoe, 2017, Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice, Autophagy, 13, 642, 10.1080/15548627.2016.1274850 Mizushima, 2004, In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker, Mol. Biol. Cell, 15, 1101, 10.1091/mbc.e03-09-0704 Neess, 2006, ACBP–a PPAR and SREBP modulated housekeeping gene, Mol. Cell. Biochem., 284, 149, 10.1007/s11010-005-9039-9 Neess, 2015, Long-chain acyl-CoA esters in metabolism and signaling: role of acyl-CoA binding proteins, Prog. Lipid Res., 59, 1, 10.1016/j.plipres.2015.04.001 Ponpuak, 2015, Secretory autophagy, Curr. Opin. Cell Biol., 35, 106, 10.1016/j.ceb.2015.04.016 Potes, 2017, Overweight in elderly people induces impaired autophagy in skeletal muscle, Free Radic. Biol. Med., 110, 31, 10.1016/j.freeradbiomed.2017.05.018 Qian, 2008, Acyl coenzyme A-binding protein (ACBP) is phosphorylated and secreted by retinal Muller astrocytes following protein kinase C activation, J. Neurochem., 105, 1287, 10.1111/j.1471-4159.2008.05229.x Qu, 2007, Autophagy gene-dependent clearance of apoptotic cells during embryonic development, Cell, 128, 931, 10.1016/j.cell.2006.12.044 Roberts, 2014, Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition, Mol. Cell, 53, 521, 10.1016/j.molcel.2013.12.019 Sakurai, 1998, Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior, Cell, 92, 573, 10.1016/S0092-8674(00)80949-6 Semerano, 2016, Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis, Angiogenesis, 19, 39, 10.1007/s10456-015-9487-0 Simon, 2017, Retrograde signaling from autophagy modulates stress responses, Sci. Signal., 10, 10.1126/scisignal.aag2791 Stienstra, 2007, PPARs, obesity, and inflammation, PPAR Res., 2007, 95974, 10.1155/2007/95974 Vacchelli, 2015, Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1, Science, 350, 972, 10.1126/science.aad0779 Wei, 2013, EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance, Cell, 154, 1269, 10.1016/j.cell.2013.08.015 Zhang, 2013, Cell biology. Unconventional secretion, unconventional solutions, Science, 340, 559, 10.1126/science.1234740