Acupuncture attenuates the development of diabetic peripheral neuralgia by regulating P2X4 expression and inflammation in rat spinal microglia

Yao DD, Shu L, Yang L, Jia XB (2014) Advance in studies on anti-diabetic mechanism of Gardeniae Fructus and its active ingredient geniposide. Zhongguo Zhong Yao Za Zhi 39:1368–1373 Pan H, Huang H, Zhang L, Ma S, Yang H, Wang H (2019) “Adjusting internal organs and dredging channel” electroacupuncture treatment prevents the development of diabetic peripheral neuropathy by downregulating glucose-related protein 78 (GRP78) and caspase-12 in streptozotocin-diabetic rats. J Diabet 11:928–937 Feng L, Liu WK, Deng L, Tian JX, Tong XL (2014) Clinical efficacy of aconitum-containing traditional Chinese medicine for diabetic peripheral neuropathic pain. Am J Chin Med 42:109–117 Boulton AJ, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R, Malik RA, Maser RE, Sosenko JM, Ziegler D (2005) Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care 28:956–962 Tesfaye S, Boulton AJ, Dickenson AH (2013) Mechanisms and management of diabetic painful distal symmetrical polyneuropathy. Diabetes Care 36:2456–2465 Garrow AP, Xing M, Vere J, Verrall B, Wang L, Jude EB (2014) Role of acupuncture in the management of diabetic painful neuropathy (DPN): a pilot RCT. Acupunct Med 32:242–249 Ites KI, Anderson EJ, Cahill ML, Kearney JA, Post EC, Gilchrist LS (2011) Balance interventions for diabetic peripheral neuropathy: a systematic review. J Geriatr Phys Ther 34:109–116 Irving G, Tanenberg RJ, Raskin J, Risser RC, Malcolm S (2014) Comparative safety and tolerability of duloxetine vs. pregabalin vs. duloxetine plus gabapentin in patients with diabetic peripheral neuropathic pain. Int J Clin Pract 68:1130–1140 Zuo L, Zhang L (2010) Study on the effect of acupuncture plus methylcobalamin in treating diabetic peripheral neuropathy. J Acupunct Tuina Sci 8:249–252 Li-Weber M (2013) Targeting apoptosis pathways in cancer by Chinese medicine. Cancer Lett 332:304–312 Anshasi HA, Ahmad M (2018) An assessment of methodological quality of systematic reviews of acupuncture and related therapies for cancer-related pain. Complement Ther Clin 32:163–168 Zhao ZQ (2008) Neural mechanism underlying acupuncture analgesia. Prog Neurobiol 85:355–375 Abuaisha BB, Costanzi JB, Boulton AJ (1998) Acupuncture for the treatment of chronic painful peripheral diabetic neuropathy: a long-term study. Diabetes Res Clin Pract 39:115–121 Tong Y, Guo H, Han B (2010) Fifteen-day acupuncture treatment relieves diabetic peripheral neuropathy. J Acupunct Meridian Stud 3:95–103 Ahn AC, Bennani T, Freeman R, Hamdy O, Kaptchuk TJ (2007) Two styles of acupuncture for treating painful diabetic neuropathy–a pilot randomised control trial. Acupunct Med 25:11–17 Chen X-M, Xu J, Song J-G, Zheng B-J, Wang X-R (2015) Electroacupuncture inhibits excessive interferon-γ evoked up-regulation of P2X4 receptor in spinal microglia in a CCI rat model for neuropathic pain. Br J Anaesth 114:150–157 Liang Y, Du JY, Qiu YJ, Fang JF, Liu J, Fang JQ (2016) Electroacupuncture attenuates spinal nerve ligation-induced microglial activation mediated by p38 mitogen-activated protein kinase. Chin J Integr Med 22:704–713 Tsuda M, Inoue K (2007) Neuropathic pain and ATP receptors in spinal microglia. Brain Nerve 59:953–959 Beggs S, Trang T, Salter MW (2012) P2X4R+ microglia drive neuropathic pain. Nat Neurosci 15:1068–1073 Inoue K (2019) Role of the P2X4 receptor in neuropathic pain. Curr Opin Pharmacol 47:33–39 DeLeo JA, Tanga FY, Tawfik VL (2004) Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist 10:40–52 Dang JK, Wu Y, Cao H, Meng B, Huang CC, Chen G, Li J, Song XJ, Lian QQ (2014) Establishment of a rat model of type II diabetic neuropathic pain. Pain Med 15:637–646 Zhang M, Lv XY, Li J, Xu ZG, Chen L (2008) The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res 2008:704045 Xu X, Liang T, Wen Q, Lin X, Tang J, Zuo Q, Tao L, Xuan F, Huang R (2014) Protective effects of total extracts of Averrhoa carambola L. (Oxalidaceae) roots on streptozotocin-induced diabetic mice. Cell Physiol Biochem 33:1272–1282 Brussee V, Guo G, Dong Y, Cheng C, Martinez JA, Smith D, Glazner GW, Fernyhough P, Zochodne DW (2008) Distal degenerative sensory neuropathy in a long-term type 2 diabetes rat model. Diabetes 57:1664–1673 Lin Y, Sun Z (2010) Current views on type 2 diabetes. J Endocrinol 204:1–11 Zhao ZM, Liu CL, Zhang QY, Zhang BB, Guo JH, Yuan AH, Cai H (2018) Acupuncture treatment reduces body weight possibly by down-regulating insulin and leptin resistance, and up-regulating soluble leptin receptor level in prediabetic patients. Zhen Ci Yan Jiu 43:506–511 Takenobu Y, Katsube N, Marsala M, Kondo K (2001) Model of neuropathic intermittent claudication in the rat: methodology and application. J Neurosci Methods 104:191–198 Hong Z, Hong H, Chen H, Wang Z, Hong D (2011) Investigation of the protective effect of erythropoietin on spinal cord injury in rats. Exp Ther Med 2:837–841 Weisberg SP, Leibel R, Tortoriello DV (2008) Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 149:3549–3558 El-Moselhy MA, Taye A, Sharkawi SS, El-Sisi SF, Ahmed AF (2011) The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids. Food Chem Toxicol 49:1129–1140 Srinivasan K, Viswanad B, Asrat L, Kaul C, Ramarao P (2005) Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol Res 52:313–320 Chao PC, Li Y, Chang CH, Shieh JP, Cheng JT, Cheng KC (2018) Investigation of insulin resistance in the popularly used four rat models of type-2 diabetes. Biomed Pharmacother 101:155–161 Zychowska M, Rojewska E, Pilat D, Mika J (2015) The role of some chemokines from the CXC subfamily in a mouse model of diabetic neuropathy. J Diabetes Res 2015:750182 Dan Y (2004) Clinical observation on therapeutic effects of acupuncture treatment for 100 cases of type II diabetes. J Acupunct Tuina Sci 2:34–35 Han D, Liu C, Qie L, Wang F, Wang Z (2015) Acupoint selection and medication rules analysis for allergic rhinitis treated with acupoint application-based on data mining technology. Zhongguo Zhen Jiu 35:1177–1180 Berman BM, Langevin HM, Witt CM, Dubner R (2010) Acupuncture for chronic low back pain. New Engl J Med 363:454–461 Bailey A, Wingard D, Allison M, Summers P, Calac D (2017) Acupuncture treatment of diabetic peripheral neuropathy in an American Indian community. J Acupunct Meridian Stud 10:90–95 Rapson LM, Wells N, Pepper J, Majid N, Boon H (2003) Acupuncture as a promising treatment for below-level central neuropathic pain: a retrospective study. J Spinal Cord Med 26:21–26 Toth CC, Jedrzejewski NM, Ellis CL, Frey WH (2010) Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain. Mol Pain 6:16 Wang D, Couture R, Hong Y (2014) Activated microglia in the spinal cord underlies diabetic neuropathic pain. Eur J Pharmacol 728:59–66 Zhuang ZY, Kawasaki Y, Tan PH, Wen YR, Huang J, Ji RR (2007) Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun 21:642–651 Old EA, Malcangio M (2012) Chemokine mediated neuron–glia communication and aberrant signalling in neuropathic pain states. Curr Opin Pharmacol 12:67–73 Lee KM, Jeon SM, Cho HJ (2009) Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model. Eur J Pain 13:794–806 Andrade P, Hoogland G, Garcia MA, Steinbusch HW, Daemen MA, Visser-Vandewalle V (2013) Elevated IL-1β and IL-6 levels in lumbar herniated discs in patients with sciatic pain. Eur Spine J 22:714–720 Zhang Z, Zhang Z-Y, Fauser U, Schluesener H (2008) Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats. Neuroscience 152:495–501 Sweitzer S, Schubert P, DeLeo J (2001) Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain. J Pharmacol Exp Ther 297:1210–1217 Tsuda M, Kohro Y, Yano T, Tsujikawa T, Kitano J, Tozaki-Saitoh H, Koyanagi S, Ohdo S, Ji RR, Salter MW, Inoue K (2011) JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. Brain 134:1127–1139 Dubový P, Klusáková I, Hradilová-Svíženská I, Joukal M, Boadas-Vaello P (2018) Activation of astrocytes and microglial cells and CCL2/CCR2 upregulation in the dorsolateral and ventrolateral nuclei of periaqueductal gray and rostral ventromedial medulla following different types of sciatic nerve injury. Front Cell Neurosci 12:40 Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Liu D, Fu S (2018) Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways. Int J Mol Sci 19:821