Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme

Journal of Molecular Biology - Tập 303 Số 3 - Trang 405-421 - 2000
J.A.R.G. Barbosa1, Brian J. Smith1, R. DeGori1, Hua Chee Ooi1,2, Salvo Marcuccio1, E.M. Campi2, W. Roy Jackson2, Reinhard Brossmer3, Monika Sommer3, Michael C. Lawrence1
1Biomolecular Research Institute, 343 Royal Parade, Parkville, Victoria, 3052, Australia
2Chemistry Department P.O. Box 23, Monash University, Victoria 3801, Australia
3Universität Heidelberg Biochemie-Zentrum, Im Neuenheimer Feld 328 69120 Heidelberg, Germany

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