Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania

PLoS Pathogens - Tập 12 Số 11 - Trang e1005971
Susan Wyllie1, Adam J. Roberts1, Suzanne Norval1, Stephen Patterson1, Bernardo J. Foth2, Matthew Berriman2, Kevin D. Read1, Alan H. Fairlamb1
1Division of Biological Chemistry and Drug Discovery, Wellcome Trust Building, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom
2Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

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