Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

New England Journal of Medicine - Tập 350 Số 21 - Trang 2129-2139 - 2004
Thomas J. Lynch1,2, Daphne W. Bell1,2, Raffaella Sordella1, Sarada Gurubhagavatula1,3, Ross A. Okimoto1, Brian W. Brannigan1, Patricia L. Harris1, Sara M. Haserlat1, Jeffrey G. Supko1,2, Frank G. Haluska1,2, David N. Louis1,4, David C. Christiani1,2,3, Jeff Settleman1,2, Daniel A. Haber1,2
1Cancer Center, Massachusetts General Hospital and Harvard Medical School
2Departments of Medicine, Massachusetts General Hospital and Harvard Medical School
3Harvard School of Public Health
4Pathology, Massachusetts General Hospital and Harvard Medical School.

Tóm tắt

Từ khóa


Tài liệu tham khảo

10.1056/NEJMoa011954

10.1056/NEJM200104053441401

Wakeling AE, 2002, Cancer Res, 62, 5749

Arteaga CL, 2003, Exp Cell Res, 284, 122, 10.1016/S0014-4827(02)00104-0

Jorissen RN, 2003, Exp Cell Res, 284, 31, 10.1016/S0014-4827(02)00098-8

Luetteke NC, 1994, Genes Dev, 8, 399, 10.1101/gad.8.4.399

Threadgill DW, 1995, Science, 269, 230, 10.1126/science.7618084

10.1200/JCO.2002.10.112

10.1200/JCO.2002.03.038

10.1200/JCO.2002.03.100

10.1001/jama.290.16.2149

10.1200/JCO.2003.10.038

10.1200/JCO.2004.08.001

10.1200/JCO.2004.07.215

Frederick L, 2000, Cancer Res, 60, 1383

10.1200/JCO.2004.08.110

Cohen MH, 2004, Clin Cancer Res, 10, 1212, 10.1158/1078-0432.CCR-03-0564

10.1093/jnci/92.3.205

10.1101/gad.1023703

Nielsen UB, 2003, Proc Natl Acad Sci U S A, 100, 9330, 10.1073/pnas.1633513100

10.1200/JCO.20.1.110

10.1074/jbc.M207135200

10.1126/science.2406902

Pegram MD, 2000, Cancer Treat Res, 103, 57, 10.1007/978-1-4757-3147-7_4

10.1200/JCO.2003.04.190

10.1038/nature00766

10.1126/science.1082596

Li B, 2003, Cancer Res, 63, 7443