Acetals as pH-Sensitive Linkages for Drug Delivery
Tóm tắt
Từ khóa
Tài liệu tham khảo
Engin K., 1995, Int. J. Hypertherm., 11
Ojugo A. S. E., 1999, Measurement of the extracellular pH of solid tumors in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes. NMR Biomed. 12, 495−504
Gallin, J. I., Goldstein, I. M., and Snyderman, R. E. (1992)Inflammation − basic principles and clinical correlates, 2nd ed., pp 511−533.
Duncan R., 2003, Nature Rev., 2
Murthy N., 2003, A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgels. Proc. Nat. Acad. Sci. 100, 4995−5000
Davis M., 2002, Nonviral gene delivery systems. Curr. Opin. Biotechnol. 13, 128−131
Wiethoff C. M., 2003, J. Pharm. Sci., 92
Greenfield R. S., 1990, Cancer Res., 50, 6600
Kaneko T., 1991, New hydrazone derivatives of Adriamycin and their immunoconjugates − a correlation between acid stability and cytotoxicity. Bioconjugate Chem. 2, 133−141
Kruger M., 1997, Synthesis and stability of four maleimide derivatives of the anticancer drug doxorubicin for the preparation of chemoimmunoconjugates. Chem. Pharm. Bull. 45, 399−401
Rodrigues P. C. A., 1999, Acid-sensitive polyethylene glycol conjugates of doxorubicin: preparation, in vitro efficacy and intracellular distribution. Bioorg. Med. Chem. 7, 2517−2524
Padilla De Jesús O. L., 2002, Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation. Bioconjugate Chem. 13, 453−461
Shen W. C., 1981, cis-Aconityl spacer between daunomycin and macromolecular carriers − a model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate. Biochem. Biophys. Res. Commun. 102, 1048−1054
Choi W. M., 1999, J. Bioact. Compat. Polym., 14
Hudecz F., 1990, Immunoconjugate design: a predictive approach for coupling of daunomycin to monoclonal antibodies. Bioconjugate Chem. 1, 197−204
Patel V. F., 1996, Novel acid labile COL1 trityl-linked 1263 difluoronucleoside immunoconjugate: synthesis, characterization, and biological activity. Bioconjugate Chem. 7, 497−510
Patel V. F., 1995, Bioorg. Med. Chem. Lett., 5
Guo X., 2001, Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG-diortho ester-lipid conjugate. Bioconjugate Chem. 12, 291−300
Srinivasachar K., 1989, New protein cross-linking reagents that are cleaved by mild acid. Biochemistry 28, 2501−2509
Tietze L. F., 1989, Proton-mediated liberation of aldophosphamide from a nontoxic prodrug: a strategy for tumor-selective activation of cytocidal drugs. Cancer Res. 49, 4179−4184
Jähde E., 1989, Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro. Cancer Res. 49, 4179−4184
Tietze L. F., 1990, Engl. 29, 782−783.
Tan H., 1999, J. Mol. Catal. A, 142
Coulson R. D., 1964, Tetrahedron Lett. 3323−3326.
Kruse C. G., 1979, Synthetic applications of 2-chlorotetrahydrofuran: protection of alcohols as tetrahydro-2-furanyl (THF) ethers. Recl. Trav. Chim. Pays-Bas. 98, 371−380
Kreevoy M. M., 1955, J. Am. Chem. Soc., 77
Gillies E. R., 2003, A new approach towards acid sensitive copolymer micelles for drug delivery. Chem. Commun. 1640−1641