Accelerated Telomere Shortening in the Human Inactive X Chromosome

Biessman, 1997, Telomere maintenance without telomerase, Chromosoma, 106, 63 Blasco, 1997, Telomere shortening and tumor formation by mouse cells lacking telomerase RNA, Cell, 91, 25, 10.1016/S0092-8674(01)80006-4 Colgin, 1999, Telomere maintenance mechanisms and cellular immortalization, Curr Opin Genet Dev, 9, 97, 10.1016/S0959-437X(99)80014-8 d'Adda di Fagagna, 1999, Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability, Nat Genet, 23, 76, 10.1038/12680 Dietzel, 1998, Evidence agaist a looped structure of the inactive human X-chromosome territory, Exp Cell Res, 240, 187, 10.1006/excr.1998.3934 Fitzgerald, 1977, Total aneuploidy and age-related sex chromosome aneuploidy in cultured lymphocytes of normal men and women, Hum Genet, 39, 329, 10.1007/BF00295428 Greider, 1996, Telomere length regulation, Annu Rev Biochem, 65, 337, 10.1146/annurev.bi.65.070196.002005 Greider, 1985, Identification of a specific telomere terminal transferase activity in Tetrahymena extracts, Cell, 43, 405, 10.1016/0092-8674(85)90170-9 Griffith, 1999, Mammalian telomeres end in a large duplex loop, Cell, 97, 503, 10.1016/S0092-8674(00)80760-6 Hande, 1999, Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice, J Cell Biol, 144, 589, 10.1083/jcb.144.4.589 Harley, 1995, Telomeres and aging, 247 Hastie, 1990, Telomere reduction in human colorectal carcinoma and with ageing, Nature, 346, 866, 10.1038/346866a0 Heard, 1997, X-chromosome inactivation in mammals, Annu Rev Genet, 31, 571, 10.1146/annurev.genet.31.1.571 Jacobs, 1963, Change in human chromosome count with age: evidence for a sex difference, Nature, 197, 1080, 10.1038/1971080a0 Jacobs, 1961, Distribution of human chromosome counts in relation to age, Nature, 191, 1178, 10.1038/1911178a0 Jeppesen, 1993, The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression, Cell, 74, 281, 10.1016/0092-8674(93)90419-Q Kirk, 1997, Block in anaphase chromosome separation caused by telomerase template mutation, Science, 275, 1478, 10.1126/science.275.5305.1478 Lansdorp, 1996, Heterogeneity in telomere length of human chromosomes, Hum Mol Genet, 5, 685, 10.1093/hmg/5.5.685 Lyon, 1961, Gene action in the X chromosome of the mouse (Mus musculus), Nature, 190, 372, 10.1038/190372a0 Martens, 1998, Short telomeres on human chromosome 17p, Nat Genet, 18, 76, 10.1038/ng0198-76 Rufer, 1999, Telomere fluorescence measurements in granulocytes and T lymphocytes subsets points to a high turnover of hematopoietic stem cells and memory T cells in early childhood, J Exp Med, 190, 157, 10.1084/jem.190.2.157 Sandell, 1993, Loss of a yeast telomere: arrest, recovery, and chromosome loss, Cell, 75, 729, 10.1016/0092-8674(93)90493-A Slijepcevic, 1998, Telomere length regulation: a view from the individual chromosome perspective, Exp Cell Res, 244, 268, 10.1006/excr.1998.4185 Slijepcevic, 1997, Telomere length, chromatin structure and chromosome fusigenic potential, Chromosoma, 106, 413, 10.1007/s004120050263 Surrallés, 1996, Analysis of loss of inactive X chromosome in interphase cells, Am J Hum Genet, 59, 1091 Surrallés, 1998, Position effect of translocations involving the inactive X chromosome: physical linkage to XIC/XIST does not lead to de novo inactivation in human differentiated cells, Cytogenet Cell Genet, 82, 58, 10.1159/000015065 Surrallés, 1998, Radiosensitivity and repair of the inactive X-chromosome: insights from FISH and immunocytogenetics, Mutat Res, 414, 117, 10.1016/S1383-5718(98)00046-1 Willard, 1996, X-chromosome inactivation, XIST, and pursuit of the X-inactivation center, Cell, 86, 5, 10.1016/S0092-8674(00)80071-9 Willard, 1976, Analysis of deoxyribonucleic acid replication in human X chromosomes by fluorescence microscopy, Am J Hum Genet, 28, 213 Zijlmans, 1997, Telomeres in the mouse have large inter-chromosomal variation in the number of T2AG3 repeats, Proc Natl Acad Sci USA, 94, 7423, 10.1073/pnas.94.14.7423