ARID1A and TERT promoter mutations in dedifferentiated meningioma

Wiemels, 2010, Epidemiology and etiology of meningioma, J Neurooncol, 99, 307, 10.1007/s11060-010-0386-3 Goutagny, 2014, High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression, Brain Pathol, 24, 184, 10.1111/bpa.12110 Abedalthagafi, 2014, Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5, Oncotarget, 5, 10596, 10.18632/oncotarget.2517 Smith, 2013, Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas, Nat Genet, 45, 295, 10.1038/ng.2552 Sahm, 2013, AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry, Acta Neuropathol, 126, 757, 10.1007/s00401-013-1187-5 Reuss, 2013, Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations, Acta Neuropathol, 125, 351, 10.1007/s00401-013-1093-x Clark, 2013, Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO, Science, 339, 1077, 10.1126/science.1233009 Brastianos, 2013, Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations, Nat Genet, 45, 285, 10.1038/ng.2526 Aavikko, 2012, Loss of SUFU function in familial multiple meningioma, Am J Hum Genet, 91, 520, 10.1016/j.ajhg.2012.07.015 Du, 2015, Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma, Oncotarget, 6, 4704, 10.18632/oncotarget.3082 Yang, 2012, Alternative splicing of CHEK2 and codeletion with NF2 promote chromosomal instability in meningioma, Neoplasia, 14, 20, 10.1593/neo.111574 Kliese, 2013, miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells, Oncogene, 32, 4712, 10.1038/onc.2012.468 Choy, 2011, The molecular genetics and tumor pathogenesis of meningiomas and the future directions of meningioma treatments, Neurosurg Focus, 30, E6, 10.3171/2011.2.FOCUS1116 Wang, 2012, RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues, J Mol Diagn, 14, 22, 10.1016/j.jmoldx.2011.08.002 Brastianos, 2014, Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas, Nat Genet, 46, 161, 10.1038/ng.2868 DePristo, 2011, A framework for variation discovery and genotyping using next-generation DNA sequencing data, Nat Genet, 43, 491, 10.1038/ng.806 McKenna, 2010, The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data, Genome Res, 20, 1297, 10.1101/gr.107524.110 Cibulskis, 2013, Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples, Nat Biotechnol, 31, 213, 10.1038/nbt.2514 International HapMap 3 Consortium, 2010, Integrating common and rare genetic variation in diverse human populations, Nature, 467, 52, 10.1038/nature09298 Browning, 2009, Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies, Am J Hum Genet, 85, 847, 10.1016/j.ajhg.2009.11.004 Carter, 2012, Absolute quantification of somatic DNA alterations in human cancer, Nat Biotechnol, 30, 413, 10.1038/nbt.2203 Riemenschneider, 2006, Histological classification and molecular genetics of meningiomas, Lancet Neurol, 5, 1045, 10.1016/S1474-4422(06)70625-1 Bostrom, 2001, Alterations of the tumor suppressor genes CDKN2A (p16INK4a), p14ARF, CDKN2B (p15INK4b), and CDKN2C (p18INK4c) in atypical and anaplastic meningiomas, Am J Pathol, 159, 661, 10.1016/S0002-9440(10)61737-3 Goutagny, 2010, Genomic profiling reveals alternative genetic pathways of meningioma malignant progression dependent on the underlying NF2 status, Clin Cancer Res, 16, 4155, 10.1158/1078-0432.CCR-10-0891 Simon, 2000, Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progression, J Neurosurg, 92, 832, 10.3171/jns.2000.92.5.0832 Wu, 2013, ARID1A mutations in cancer: another epigenetic tumor suppressor?, Cancer Disc, 3, 35, 10.1158/2159-8290.CD-12-0361 Guan, 2011, ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers, Cancer Res, 71, 6718, 10.1158/0008-5472.CAN-11-1562 Dykhuizen, 2013, BAF complexes facilitate decatenation of DNA by topoisomerase II α, Nature, 497, 624, 10.1038/nature12146 Eroglu, 2014, SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells, Cell, 156, 1259, 10.1016/j.cell.2014.01.053 Kadoch, 2014, Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy, Nat Genet, 45, 592, 10.1038/ng.2628 Craig, 2012, DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues, PLoS One, 7, e38881, 10.1371/journal.pone.0038881