APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study

Journal of Lipid Research - Tập 46 Số 3 - Trang 564-570 - 2005
Kathy L.E. Klos1, Sara Hamon2, Andrew G. Clark3, Eric Boerwinkle4, Kiang Liu5, Charles F. Sing2
1University of Texas Health Science Center at Houston
2Department of Human Genetics, University of Michigan, Ann Arbor, MI
3(Cornell University
4Human Genetics Center, University of Texas Health Science Center, Houston, TX
5Department of Preventive Medicine, Northwestern University, Chicago, IL

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Assmann, 1998, The emergence of triglycerides as a significant independent risk factor in coronary artery disease, Eur. Heart J., 19, 8

Austin, 1998, Hypertriglyceridemia as a cardiovascular risk factor, Am. J. Cardiol., 81, 7B, 10.1016/S0002-9149(98)00031-9

Hunt, 1989, Genetic heritability and common environmental components of resting and stressed blood pressure, lipids, and body mass index in Utah pedigrees and twins, Am. J. Epidemiol., 129, 625, 10.1093/oxfordjournals.aje.a115175

Brenn, 1994, Genetic and environmental effects on coronary heart disease risk factors in northern Norway. The Cardiovascular Disease Study in Finnmark, Ann. Hum. Genet., 58, 369, 10.1111/j.1469-1809.1994.tb00733.x

Pennacchio, 2001, An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing, Science., 294, 169, 10.1126/science.1064852

Talmud, 2002, Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides, Hum. Mol. Genet, 11, 3039, 10.1093/hmg/11.24.3039

Pennacchio, 2002, Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels, Hum. Mol. Genet., 11, 3031, 10.1093/hmg/11.24.3031

Baum, 2003, APOA5− 1131T>C polymorphism is associated with triglyceride levels in Chinese males, Clin. Genet., 63, 377, 10.1034/j.1399-0004.2003.00063.x

Eichenbaum-Voline, 2003, Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia, Arterioscler. Thromb. Vasc. Biol., 23, 2070

Evans, 2003, The single nucleotide polymorphism −1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia, J. Mol. Med., 81, 645, 10.1007/s00109-003-0465-4

Horinek, 2003, T-1131-C polymorphism within the apolipoprotein AV gene in hypertriglyceridemic individuals, Atherosclerosis., 167, 369, 10.1016/S0021-9150(03)00022-4

Kao, 2003, A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia, Hum. Mol. Genet., 12, 2533, 10.1093/hmg/ddg255

Lai, 2003, The apolipoprotein A5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore, J. Lipid Res., 44, 2365, 10.1194/jlr.M300251-JLR200

Martin, 2003, Contribution of APOA5 variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges, Biochim. Biophys. Acta., 1637, 217, 10.1016/S0925-4439(03)00033-4

Vrablik, 2003, Ser19-Trp polymorphism within the apolipoprotein AV gene in hypertriglyceridaemic people, J. Med. Genet, 40, e105, 10.1136/jmg.40.8.e105

Hubacek, 2004, The influence of APOAV polymorphisms (T−1131>C and S19>W) on plasma triglyceride levels and risk of myocardial infarction, Clin. Genet., 65, 126, 10.1111/j.0009-9163.2004.00199.x

Austin, 2004, Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans, Biochim. Biophys. Acta., 1688, 1, 10.1016/j.bbadis.2003.10.003

Li, 2004, Genetic effect of two polymorphisms in the apolipoprotein A5 gene and apolipoprotein C3 gene on serum lipids and lipoproteins levels in a Chinese population, Clin. Genet., 65, 470, 10.1111/j.1399-0004.2004.00251.x

Lai, 2004, Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study, J. Lipid Res, 45, 2096, 10.1194/jlr.M400192-JLR200

Friedman, 1988, CARDIA: study design, recruitment, and some characteristics of the examined subjects, J. Clin. Epidemiol., 41, 1105, 10.1016/0895-4356(88)90080-7

Warnick, 1986, Enzymatic methods for quantification of lipoprotein lipids, Methods Enzymol., 129, 101, 10.1016/0076-6879(86)29064-3

Fullerton, 2004, The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster, Hum. Genet., 115, 36, 10.1007/s00439-004-1106-x

Weir, 1996

Stephens, 2001, A new statistical method for haplotype reconstruction from population data, Am. J. Hum. Genet., 68, 978, 10.1086/319501

Stephens, 2003, A comparison of Bayesian methods for haplotype reconstruction, Am. J. Hum. Genet., 73, 1162, 10.1086/379378

Levene, 1960, Robust tests for equality of variance, 278

Sokal, 1998

Welch, 1951, On the comparison of several mean values: an alternative approach, Biometrika., 38, 330, 10.1093/biomet/38.3-4.330

Boerwinkle, 1986, Bias of the contribution of single locus effects to the variance of a quantitative trait, Am. J. Hum. Genet., 39, 137

Kaprio, 1991, Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease, Arterioscler. Thromb., 11, 1330, 10.1161/01.ATV.11.5.1330