ANTIBODIES TO RIBONUCLEAR PROTEINS

Abuaf, 1990, Detection of autoantibodies to Sm antigen in systemic lupus erythematosus by immunodiffusion, ELISA and immunoblotting: Variability of incidence related to assays and ethnic origin of patients, Eur, J Clin Invest, 20, 354 Alexander, 1983, Sjögren’s syndrome: Association of anti-Ro (SSA) antibodies with vasculitis, hematologic abnormalities and serologic hyperreactivity, Ann Intern Med, 98, 155, 10.7326/0003-4819-98-2-155 Alexander, 1989, The immunogenetic relationship between anti-Ro/SSA/La/SSB antibody positive Sjögren’s/lupus erythematosus over-lap syndrome and the neonatal lupus syndrome, J Invest Dermatol, 93, 751, 10.1111/1523-1747.ep12284404 Arnett, 1988, Increased frequencies of Sm and URNP autoantibodies in American Blacks compared to Whites with systemic lupus erythematosus, J Rheumatol, 15, 1773 Bach, 1991, Protein RNA interactions in 20s U5 SnRNP, Biochim Biophys Acta, 1088, 139, 10.1016/0167-4781(91)90164-H Bach, 1989, 20s small ribonuclear protein U5 shows a surprisingly complex protein composition, Proc Natl Acad Sci USA, 86, 6038, 10.1073/pnas.86.16.6038 Barada, 1981, Antibodies to Sm in patients with systemic lupus erythematosus, Arthritis Rheum, 24, 1236, 10.1002/art.1780241003 Ben-Chetrit, 1988, A 52 kD protein is a novel component of the SS-A/Ro antigenic particle, J Exp Med, 167, 1560, 10.1084/jem.167.5.1560 Ben-Chetrit, 1989, Isolation and characterization of a cDNA clone encoding the 60 Kd component of the human SS-A/Ro ribonucleoprotein antigen, J Clin Invest, 83, 1284, 10.1172/JCI114013 Buyon, 1989, Acquired congenital heart block. Pattern of maternal antibody response to biochemicals defined antigens of the SSA/Ro, SSB/La system in neonatal lupus, J Chem Invest, 84, 627, 10.1172/JCI114208 Callen, 1985, Neonatal lupus erythematosus occurring in one fraternal twin, Arthritis Rheum, 28, 271, 10.1002/art.1780280306 Craft, 1988, The U2 small nuclear ribonucleoprotein particle as an autoantigen: Analysis with sera from patients with overlap syndrome, J Clin Invest, 8, 1716, 10.1172/JCI113511 Deng, 1987, Localization of Ro/SSA antigen in the cardiac conduction system, Arthritis Rheum, 30, 1232, 10.1002/art.1780301105 Deutscher, 1988, Molecular analysis of the 60 kDa human Ro ribonucleoprotein, Proc Natl Acad Sci USA, 85, 9479, 10.1073/pnas.85.24.9479 Elkon, 1989, Association between anti-Sm and anti-ribosomal P protein antibodies in human systemic lupus erythematosus and MRL/lpr mice, J Immunol, 143, 1549, 10.4049/jimmunol.143.5.1549 Elkon, 1985, Lupus autoantibodies target ribosomal P proteins, J Exp Med, 162, 459, 10.1084/jem.162.2.459 Gripenberg, 1991, Antibodies to Sm and SS-A demonstrated by enzyme immunoassay, Rheumatol Int, 11, 209, 10.1007/BF00332564 Guldner, 1988, Epitope mapping with a recombinant human 60-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human sera, J Immunol, 141, 469, 10.4049/jimmunol.141.2.469 Habets, 1983, Antibodies against distinct nuclear matrix proteins are characteristic for mixed connective tissue disease, Clin Exp Immunol, 54, 265 Habets, 1989, Detection of autoantibodies in a quantitative immunoassay using recombinant ribonucleoprotein antigens, Clin Exp Immunol, 76, 172 Habets, 1989, Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes, Proc Natl Acad Sci USA, 86, 4674, 10.1073/pnas.86.12.4674 Hamilton, 1988, Two Ro (SS-A) antibody responses in systemic lupus erythematosus: Correlation of HLA-DR/DQ specificities with quantitative expression of Ro (SS-A) autoantibody, Arthritis Rheum, 31, 496, 10.1002/art.1780310406 Harley, 1985, Ro/SSA antibody and antigen in congenital complete heart block, Arthritis Rheum, 28, 1321, 10.1002/art.1780281202 Harley, 1989, A model for disease heterogeneity of systemic lupus erythematosus. Relationship between histocompatibility antigens, autoantibodies, and lymphopenia to renal disease, Arthritis Rheum, 32, 826, 10.1002/j.2326-5205.1989.tb00013.x Harley, 1992, Anti-Ro in Sjögren’s syndrome and systemic lupus erythematosus, Rheum Dis Clin North Am, 18, 337, 10.1016/S0889-857X(21)00731-6 Hedgpeth, 1988, Interstitial pneumonitis in antinuclear antibody negative systemic lupus erythematosus: A new clinical manifestation and possible association with anti-Ro (SS-A) antibodies, Arthritis Rheum, 31, 545, 10.1002/art.1780310412 Hochberg, 1985, Systemic lupus erythematosus: A review of clinicolaboratory features and immunogenetic markers in 150 patients with emphasis in demographic subsets, Medicine, 64, 285, 10.1097/00005792-198509000-00001 Hoet, 1992, Changes in anti U1RNA antibody levels correlate with disease activity in patients with SLE overlap syndrome, Arthritis Rheum, 9, 1202, 10.1002/art.1780351013 Houtman, 1985, Quantitation of antibodies to nucleoribonucleoprotein by ELISA: Relation between antibody levels and disease activity in patients with connective tissue disease, Clin Exp Immunol, 62, 696 Itoh, 1992, Autoantibodies to the Ro/SSA antigen are conformation dependent. II: Antibodies to the denatured form of 52 kD Ro/SSA are a crossreacting subset of antibodies to the native 60 kD Ro/SSA molecule, Autoimmunity, 14, 89, 10.3109/08916939209083125 Itoh, 1990, Isoforms of Ro/SSA, Clin Exp Immunol, 81, 45, 10.1111/j.1365-2249.1990.tb05289.x Itoh, 1992, Autoantibodies to the Ro/SSA antigen are conformation dependent. I: Anti-60 kD antibodies are mainly directed to the native protein; anti-52 kD antibodies are mainly directed to the denatured protein, Autoimmunity, 14, 57, 10.3109/08916939309077357 Kephart, 1981, Neonatal lupus: Serologic findings, J Invest Dermatol, 77, 331, 10.1111/1523-1747.ep12482531 Lee, 1986, An animal model of antibody binding in cutaneous lupus, Arthritis Rheum, 29, 782, 10.1002/art.1780290612 Lee, 1989, The pattern of cutaneous IgG deposition in a case of subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin in grafted mice, J Clin Invest, 83, 1556, 10.1172/JCI114052 Litsky, 1985, Maternal connective tissue disease and congenital heart block. 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Association with anti-Ro (SS-A) antibodies, Clin Exp Immunol, 62, 678 Michaelsson, 1972, Complete congenital heart block: An international study of the natural history, Cardiovasc Clin, 4, 87 Mimori, 1991, Newly identified autoantibodies to U4/U6 small nuclear ribonucleoprotein particle in a patient with primary Sjögren’s syndrome, Arthritis Rheum, 34, S46 Miyagawa, 1982, Placental transfer of anticytoplasmic antibodies in annular erythema of newborns, Arch Dermatol, 117, 569, 10.1001/archderm.1981.01650090051026 Mond, 1989, Correlation of anti-Ro antibody with photosensitivity, rash in systemic lupus erythematosus patients, Arthritis Rheum, 32, 202, 10.1002/anr.1780320213 Netter, 1988, A recombinant autoantigen derived from the human (U1) small nuclear RNP-specific 68 kD protein, Arthritis Rheum, 31, 616, 10.1002/art.1780310506 Nimelstein, 1980, Mixed connective tissue disease: A subsequent evaluation of the original 25 patients, Medicine, 59, 239, 10.1097/00005792-198007000-00001 Notman, 1975, Profiles of antinuclear antibodies in systemic rheumatic diseases, Ann Intern Med, 83, 464, 10.7326/0003-4819-83-4-464 Ohosone, 1992, Autoantigenic epitopes of the B polypeptide of Sm small nuclear RNP particles, Arthritis Rheum, 35, 960, 10.1002/art.1780350818 Okano, 1991, Newly identified U4/U6 SnRNP binding proteins by serum autoantibodies from a patient with systemic sclerosis, J Immunol, 146, 535, 10.4049/jimmunol.146.2.535 Parker, 1973, Ribonucleoprotein antibodies: Frequency and clinical significance in systemic lupus erythematosus, scleroderma, and mixed connective tissue disease, J Lab Clin Med, 82, 769 Petterson, 1984, The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti (U1) ribonudeoproteins and anti-Sm autoantibodies, J Biol Chem, 259, 5907, 10.1016/S0021-9258(18)91101-4 Petterson, 1986, The use of immunoblotting and immunoprecipitation of U small nuclear ribonucleoproteins in the analysis of sera of patients with mixed connective tissue disease and systemic lupus erythematosus, Arthritis Rheum, 29, 986, 10.1002/art.1780290807 Powers, 1977, Substantial purification of the Sm antigen and association of high titer antibody to Sm with a clinical subset of systemic lupus erythematosus [abstract], Arthritis Rheum, 20, 131 Provost, 1983, Neonatal lupus, Arch Dermatol, 119, 619, 10.1001/archderm.1983.01650310081019 Provost, 1983, Homozygous C2 deficiency, lupus erythematosus and anti-Ro/SSA antibodies, Arthritis Rheum, 26, 1279, 10.1002/art.1780261017 Provost, 1988, Ro/SSA positive Sjögren’s/lupus erythematosus (SCLE) overlap patients are associated with the HL4-DR3 and/or DRW6 phenotypes, J Invest Dermatol, 91, 369, 10.1111/1523-1747.ep12476204 Provost, 1988, The relationship between anti-Ro/SSA antibody positive Sjögren’s syndrome and anti-Ro/SSA antibody positive lupus erythematosus, Arch Dermatol, 124, 63, 10.1001/archderm.1988.01670010027017 Rader, 1989, Heterogeneity of the Ro/SSA antigen. Different molecular forms in lymphocytes and red blood cells, J Clin Invest, 83, 1293, 10.1172/JCI114014 Reichlin, 1987, Measurement of antibodies to Sm and nRNP by ELISA: Clinical and serological correlation, 85 Reichlin, 1992, Two sisters producing anti-U1RNP exhibit serological concordance and clinical discordance, Lupus, 1, 249, 10.1177/096120339200100408 Reichlin, 1987, Antibodies to Ro/SSA and the heterogeneity of SLE, J Rheumatol Suppl, 14, 112 Reichlin, 1986, Detection by ELISA of antibodies to small RNA protein particles in SLE patients whose sera lack precipitins, Trans Assoc Am Physicians, 99, 161 Reichlin, 1972, Correlation of a precipitin reaction to an RNA protein antigen and a low prevalence of nephritis in patients with systemic lupus erythematosus, N Engl J Med, 86, 908, 10.1056/NEJM197204272861702 Reichlin, 1991, Autoantibodies to URNP particles: Relationship to clinical diagnosis and nephritis, Clin Exp Immunol, 83, 286, 10.1111/j.1365-2249.1991.tb05629.x Scott, 1982, Connective-tissue death, antibodies to ribonucleoprotein and congenital heart block, N Engl J Med, 309, 209, 10.1056/NEJM198307283090403 Sharp, 1971, Association of autoantibodies to different nuclear antigens with clinical patterns of rheumatic disease and responsiveness to therapy, J Clin Invest, 50, 350, 10.1172/JCI106502 Sharp, 1972, Mixed connective tissue disease—an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA), Am J Med, 52, 148, 10.1016/0002-9343(72)90064-2 St. Clair, 1992, Anti-La antibodies, Rheum Dis Clin North Am, 18, 359, 10.1016/S0889-857X(21)00732-8 St. Clair, 1990, Expression of autoantibodies to RNP-associated 70 k antigen in systemic lupus erythematosus, Clin Immunol Immunopathol, 54, 266, 10.1016/0090-1229(90)90088-8 Sontheimer, 1982, Serologic and HLA associations in subacute cutaneous lupus erythematosus, a clinical subset of lupus erythematosus, Ann Intern Med, 97, 664, 10.7326/0003-4819-97-5-664 Sontheimer, 1981, Human histocompatibility antigenic associations in subacute cutaneous lupus erythematosus, J Clin Invest, 67, 312, 10.1172/JCI110029 Takeda, 1989, Enzyme linked immunosorbent assay using isolated (U) small nuclear ribonucleoprotein polypeptides as antigens to investigate the clinical significance of autoantibodies to these polypeptides, Clin Immunol Immunopathol, 50, 213, 10.1016/0090-1229(89)90130-X Van Venrooij, 1990, Anti U1 small RNA antibodies in anti-small ribonucleoprotein sera from patients with connective tissue disease, J Clin Invest, 86, 2154, 10.1172/JCI114954 Venables, 1983, Purification and characterization of the Sjögren’s syndrome A and B antigens, Clin Exp Immunol, 54, 731 Wasicek, 1982, Clinical and serological differences between systemic lupus erythematosus patients with antibodies to RD versus patients with antibodies to Ro and La, J Chem Invest, 69, 835, 10.1172/JCI110523 Winfield, 1978, Serologic studies in patients with systemic lupus erythematosus and central nervous system dysfunction, Arthritis Rheum, 21, 289, 10.1002/art.1780210301 Winn, 1979, Identification of a clinical subset of systemic lupus erythematosus by antibodies to the Sm antigen, Arthritis Rheum, 22, 1334, 10.1002/art.1780221203 Yamagata, 1984, Molecular properties of the Ro/SSA antigen and ELISA for quantitation of antibody, J Clin Invest, 74, 625, 10.1172/JCI111460