AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia

Journal of Molecular Signaling
Gilles M. Leclerc1, Guy J. Leclerc1, Guilian Fu1, Julio C. Barredo2
1Department of Pediatric Hematology-Oncology, University of Miami Miller School of Medicine, 1601 N.W. 12th Avenue, Miami, FL 33136 USA
2Department of Pediatric Hematology-Oncology, University of Miami Miller School of Medicine, 1601 N.W. 12th Avenue, Miami, FL 33136 USA Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 1011 N.W. 15th Street, Miami, FL 33101 USA Sylvester Comprehensive Cancer Center, University of Miami Hospital and Clinics, 1475 N.W. 12th Avenue, Miami, FL 33136 USA

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Journal of Molecular Signaling

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