ALeRT-COVID: Attentive Lockdown-awaRe Transfer Learning for Predicting COVID-19 Pandemics in Different Countries

Journal of Healthcare Informatics Research - Tập 5 - Trang 98-113 - 2021
Yingxue Li1, Wenxiao Jia1, Junmei Wang1, Jianying Guo1, Qin Liu1, Xiang Li1, Guotong Xie1,2,3, Fei Wang4
1Ping An Healthcare Technology, Beijing, China
2Ping An Health Cloud Company Limited, Beijing, China
3Ping An International Smart City Technology Co., Ltd., Beijing, China
4Cornell University, Ithaca, USA

Tóm tắt

Countries across the world are in different stages of COVID-19 trajectory, among which many have implemented lockdown measures to prevent its spread. Although the lockdown is effective in such prevention, it may put the economy into a depression. Predicting the epidemic progression with the government switching the lockdown on or off is critical. We propose a transfer learning approach called ALeRT-COVID using attention-based recurrent neural network (RNN) architecture to predict the epidemic trends for different countries. A source model was trained on the pre-defined source countries and then transferred to each target country. The lockdown measure was introduced to our model as a predictor and the attention mechanism was utilized to learn the different contributions of the confirmed cases in the past days to the future trend. Results demonstrated that the transfer learning strategy is helpful especially for early-stage countries. By introducing the lockdown predictor and the attention mechanism, ALeRT-COVID showed a significant improvement in the prediction performance. We predicted the confirmed cases in 1 week when extending and easing lockdown separately. Our results show that lockdown measures are still necessary for several countries. We expect our research can help different countries to make better decisions on the lockdown measures.

Tài liệu tham khảo

COVID-19 Coronavirus Tracker. Available at https://www.kff.org/coronavirus-covid-19/fact-sheet/coronavirus-tracker/. Accessed 1 June 2020 Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A et al (2020) Olfactory and gustatory dysfunctions as a clinical presentation of mil-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. Eur Arch Otorhinolaryngol 277(8):2251–2261 Bedford J, Enria D, Giesecke J, Heymann DL, Ihekweazu C, Kobinger G et al (2020) COVID-19: towards controlling of a pandemic. Lancet 395(10229):1015–1018 Pan A, Liu L, Wang C, Guo H, Hao X, Wang Q et al (2020) Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China. JAMA 323(19):1915–1923 Peak CM, Childs LM, Grad YH, Buckee CO (2017) Comparing nonpharmaceutical interventions for containing emerging epidemics. Proc Natl Acad Sci 114(15):4023–4028 Prem K, Liu Y, Russell TW, Kucharski AJ, Eggo RM, Davies N et al (2020) The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. Lancet Public Health 5(5):e261–e270 Habibi R, Burci GL, de Campos TC, Chirwa D, Cinà M, Dagron S et al (2020) Do not violate the International Health Regulations during the COVID-19 outbreak. Lancet 395(10225):664–666 Hossain M, Junus A, Zhu X, Jia P, Wen TH, Pfeiffer D, Yuan HY (2020) The effects of border control and quarantine measures on global spread of COVID-19. Epidemics. https://doi.org/10.1016/j.epidem.2020.100397 Kraemer MU, Yang CH, Gutierrez B, Wu CH, Klein B, Pigott DM et al (2020) The effect of human mobility and control measures on the COVID-19 epidemic in China. Science 368(6490):493–497 Chinazzi M, Davis JT, Ajelli M, Gioannini C, Litvinova M, Merler S et al (2020) The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak. Science 368(6489):395–400 Bertuzzo E, Mari L, Pasetto D, Miccoli S, Casagrandi R, Gatto M, Rinaldo A (2020) The geography of COVID-19 spread in Italy and implications for the relaxation of confinement measures. medRxiv Dev SM, Sengupta R (2020) Covid-19: impact on the Indian economy. Indira Gandhi Institute of Development Research, Mumbai Singh S, Parmar KS, Kumar J, Makkhan SJS (2020) Development of new hybrid model of discrete wavelet decomposition and autoregressive integrated moving average (ARIMA) models in application to one month forecast the casualties cases of COVID-19. Chaos, Solitons & Fractals 135. https://doi.org/10.1016/j.chaos.2020.109866 Zhao Z, Li X, Liu F, Zhu G, Ma C, Wang L (2020) Prediction of the COVID-19 spread in African countries and implications for prevention and controls: a case study in South Africa, Egypt, Algeria, Nigeria, Senegal and Kenya. Sci Total Environ 138959 Zheng N, Du S, Wang J, Zhang H, Cui W, Kang et al (2020) Predicting covid-19 in china using hybrid AI model. IEEE Trans Cybern 50(7):2891–2904 Singh RK, Rani M, Bhagavathula AS, Sah R, Rodriguez-Morales AJ, Kalita H et al (2020) Prediction of the COVID-19 pandemic for the top 15 affected countries: advanced autoregressive integrated moving average (ARIMA) model. JMIR Public Health Surveill 6(2):e19115 Verma V, Vishwakarma RK, Verma A, Nath DC, Khan HT (2020) Time-to-death approach in revealing chronicity and severity of COVID-19 across the world. PLoS One 15(5):e0233074 Chen FH (2006) A susceptible-infected epidemic model with voluntary vaccinations. J Math Biol 53(2):253–272 Kermack WO, McKendrick AG (1927) A contribution to the mathematical theory of epidemics. Proc R Soc Lond Ser A, Containing papers of a Mathematical and Physical Character 115(772):700–721 Li MY, Graef JR, Wang L, Karsai J (1999) Global dynamics of a SEIR model with varying total population size. Math Biosci 160(2):191–213 Yang Z, Zeng Z, Wang K, Wong SS, Liang W, Zanin M et al (2020) Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions. J Thorac Dis 12(3):165 López L, Rodo X (2020) A modified SEIR model to predict the COVID-19 outbreak in Spain and Italy: simulating control scenarios and multi-scale epidemics. Results Phys. https://doi.org/10.1016/j.rinp.2020.103746 Zhan C, Chi KT, Fu Y, Lai Z, Zhang H (2020) Modeling and prediction of the 2019 coronavirus disease spreading in China incorporating human migration data. medRxiv Jia W, Wan Y, Li Y, Tan K, Lei W, Hu Y et al (2019) Integrating multiple data sources and learning models to predict infectious diseases in China. AMIA Summits Transl Sci Proc 680:2019 Goodfellow I, Bengio Y, Courville A, Bengio Y (2016) Deep Learning (Vol. 1). MIT press, Cambridge Chen XW, Lin X (2014) Big data deep learning: challenges and perspectives. IEEE Access 2:514–525 Coronavirus Update (Live): 6,573,585 cases and 388,041 deaths from COVID-19 virus pandemic - Worldometer. Available at https://www.worldometers.info/coronavirus/ (2020). Accessed 14 May 2020 Coronavirus (COVID-19) Lockdown Tracker | Aura Vision. Available at https://auravision.ai/covid19-lockdown-tracker/ (2020). Accessed 14 May 2020 Wikipedia. List of countries and dependencies by population. Available at https://en.wikipedia.org/w/index.php?title=List_of_countries_and_dependencies_by_population&oldid=960653268 (2020). Accessed 14 May 2020 Hochreiter S, & Schmidhuber J (1997) Long short-term memory. Neural Comput 9(8): 1735–1780 Bahdanau D, Cho K, Bengio Y (2014) Neural machine translation by jointly learning to align and translate. arXiv:1409.0473 Gulli A, Pal S (2017) Deep learning with Keras. Packt Publishing Ltd Kingma DP, Ba J (2014) Adam: A method for stochastic optimization. arXiv preprint arXiv:1412.6980 Ruder S (2016) An overview of gradient descent optimization algorithms. arXiv preprint arXiv:1609.04747 Wang G, Huang NE, & Qiao F (2020) Quantitative evaluation on control measures for an epidemic: a case study of COVID-19. Kexue Tongbao/Chinese Science Bulletin 65(11) Pan SJ, Yang Q (2009) A survey on transfer learning. IEEE Trans Knowl Data Eng 22(10):1345–1359 Aldhyani TH, Alrasheed M, Alzahrani MY, Ahmed H (2020) Deep learning and Holt-trend algorithms for predicting COVID-19 pandemic. medRxiv Huang NE, Qiao F (2020) A data driven time-dependent transmission rate for tracking an epidemic: a case study of 2019-nCoV. Sci Bull 65(6):425–427 Konečný J, Liu J, Richtárik P, & Takáč M (2015) Mini-batch semi-stochastic gradient descent in the proximal setting. IEEE Journal of Selected Topics in Signal Processing, 10(2):242–255