ACTH 1–17 effects in intrinsic bronchial asthma
Tóm tắt
We have studied the effect of Synchrodyn® 1–17 (100 μg/day/15 days, intramuscularly) on 12 patients with intrinsic asthma, presenting a circadian pattern in several functional parameters related to the bronchial patency (and/or with bouts of nocturnal asthma). Treatment with ACTH 1–17 had two main effects: the pathological rhythms of the bronchial tone disappeared and there was a clear general improvement in the indices of bronchial patency. The drug was well tolerated. Euphoria and water retention were the side effects: they were noticed in a variable number of subjects and disappeared after discontinuation of treatment.
Tài liệu tham khảo
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