A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis

Galle, 1996, Apoptosis in liver disease, J Hepatol, 27, 405, 10.1016/S0168-8278(97)80189-4 Rehermann, 2000, Intrahepatic T cells in hepatitis B: viral control versus liver cell injury, J Exp Med, 191, 1263, 10.1084/jem.191.8.1263 Maini, 2000, The role of virus-specific CD8+ cells in liver damage and viral control during persistent Hepatitis B infection, J Exp Med, 191, 1269, 10.1084/jem.191.8.1269 Lee, 1993, Acute Liver Failure, N Engl J Med, 329, 1862, 10.1056/NEJM199312163292508 Shakil, 2000, Acute liver failure: clinical features, outcome analysis, and applicability of prognostic criteria, Liver Transpl, 6, 163 Hockenbery, 1999, BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death, Proc Natl Acad Sci U S A, 88, 6961, 10.1073/pnas.88.16.6961 de la Coste, 1999, Differential protective effects of Bcl-xL and Bcl-2 on apoptotic liver injury in transgenis mice, Am J Physiol, 277, G702 Lacronique, 1996, Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice, Nat Med, 2, 80, 10.1038/nm0196-80 Galanos, 1979, Galactosamine-induced sensitization to the lethal effects of endotoxin, Proc Natl Acad Sci U S A, 76, 5939, 10.1073/pnas.76.11.5939 Rahman, 2000, Animal models of acute hepatic failure, Int J Exp Pathol, 81, 145, 10.1046/j.1365-2613.2000.00144.x Opipari, 1990, The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein, J Biol Chem, 265, 14705, 10.1016/S0021-9258(18)77165-2 Opipari, 1992, The A20 zinc finger protein protects cells from TNF cytotoxicity, J Biol Chem, 267, 12424, 10.1016/S0021-9258(18)42292-2 Sarma, 1995, Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis, J Biol Chem, 270, 12343, 10.1074/jbc.270.21.12343 Grey, 1999, A20 inhibits cytokine-induced apoptosis and nuclear factor κB-dependent gene activation in islets, J Exp Med, 190, 1135, 10.1084/jem.190.8.1135 Ferran, 1998, A20 inhibits NF-κB activation in endothelial cells without sensitizing to TNF-mediated apoptosis, Blood, 91, 2249, 10.1182/blood.V91.7.2249 Cooper, 1996, A20 blocks endothelial cell activation through a NF-κB-dependent mechanism, J Biol Chem, 271, 18068, 10.1074/jbc.271.30.18068 Daniel, 2001, Overexpression of A20 in endothelial cells of vascularized Grafts creates a protective barrier against TNF and FAS-mediated apoptosis, Transpl Proc, 33, 225, 10.1016/S0041-1345(00)01984-9 Laherty, 1993, Human T cell leukemia virus type I Tax and phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger protein by distinct mechanisms involving nuclear factor κB, J Biol Chem, 268, 5032, 10.1016/S0021-9258(18)53498-0 Bach, 1997, Protective genes expressed in endothelial cells: a regulatory response to injury, Immunol Today, 18, 483, 10.1016/S0167-5699(97)01129-8 Lee, 2000, Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice, Science, 289, 2350, 10.1126/science.289.5488.2350 Ferran, 1996, Expression of a truncated form of the human p55 TNF-Receptor in bovine aortic endothelial cells renders them resistant to human TNF, Transpl Proc, 28, 618 Carithers, 2000, Liver Transplantation, Liver Transpl, 6, 122, 10.1002/lt.500060122 Baeuerle, 1996, NF-κB: ten years later, Cell, 87, 13, 10.1016/S0092-8674(00)81318-5 Li, 1993, Assessment of recombinant adenoviral vectors for hepatic gene therapy, Hum Gene Ther, 4, 403, 10.1089/hum.1993.4.4-403 Engelhardt, 1994, Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver, Proc Natl Acad Sci U S A, 91, 6196, 10.1073/pnas.91.13.6196 Strauss, 1994, Liver-directed gene therapy: prospects and problems, Gene Ther, 1, 156 Rodriguez, 1996, A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody, J Exp Med, 183, 1031, 10.1084/jem.183.3.1031 Li, 2000, Inhibition of Fas-mediated fulminant hepatitis in CrmA gene-transfected mice, Biochem Biophys Res Commun, 273, 101, 10.1006/bbrc.2000.2888 Huang, 1999, Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL, Proc Natl Acad Sci U S A, 96, 14871, 10.1073/pnas.96.26.14871 Wang, 1996, TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB, Science, 274, 784, 10.1126/science.274.5288.784 Marusawa, 1999, Hepatitis C virus core protein inhibits Fas- and tunor necrosis factor alpha-mediated apoptosis via NF-κB activation, J Virol, 73, 4713, 10.1128/JVI.73.6.4713-4720.1999 Zwacka, 1998, Redox gene therapy for ishemia/reperfusion injury of the liver reduces AP1 and NF-κB activation, Nat Med, 4, 698, 10.1038/nm0698-698 VanAntwerp, 1996, Suppression of TNF-α-induced apoptosis by NF-κB, Science, 274, 787, 10.1126/science.274.5288.787 Santucci, 1996, Interleukin 10 reduces lethality and hepatic injury induced by lipolysaccharide in galctosamine-sensitized mice, Gastroenterology, 111, 736, 10.1053/gast.1996.v111.pm8780580 Barton, 1993, Protective role of interleukin 6 in the lipopolysaccharide-galactosamine septic shock model, Infect Immun, 61, 1496, 10.1128/IAI.61.4.1496-1499.1993 Yamada, 1997, Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor, Proc Natl Acad Sci U S A, 94, 1441, 10.1073/pnas.94.4.1441 Limuro, 1998, NF-κB prevents apoptosis and liver dysfunction during liver regeneration, J Clin Invest, 101, 802, 10.1172/JCI483 Kondo, 1997, Essential roles of the Fas ligand in the development of hepatitis, Nat Med, 3, 409, 10.1038/nm0497-409 Desbarats, 2000, Fas engagement accelerates liver regeneration after partial hepatectomy, Nat Med, 6, 920, 10.1038/78688 Cressman, 1996, Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice, Science, 274, 1379, 10.1126/science.274.5291.1379 Fausto, 2000, Liver regeneration, J Hepatol, 32, 19, 10.1016/S0168-8278(00)80412-2 Kay, 2001, Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics, Nat Med, 7, 33, 10.1038/83324