A trial of Ro 03-8799 (pimonidazole) in carcinoma of the uterine cervix: an interim report from the Medical Research Council Working Party on advanced carcinoma of the cervix

Altman, 1991 BMDP, 1988, Vol. 2 Broders, 1925, Grading of carcinoma, Minn. Med., 8, 726 Chaplin, 1992, Tumor blood flow changes induced by chemical modifiers of radiation response, Int. J. Radiat. Oncol. Biol. Phys., 22, 459, 10.1016/0360-3016(92)90853-A COMPACT Steering Committee, 1991, Improving the quality of data in clinical trials in cancer, Br. J. Cancer, 63, 412, 10.1038/bjc.1991.95 FIGO, 1985, Vol. 19 Fletcher, 1977, Hyperbaric oxygen as a radiotherapeutic adjuvant in advanced carcinoma of the uterine cervix. Preliminary results of a randomised trial, Cancer, 39, 617, 10.1002/1097-0142(197702)39:2<617::AID-CNCR2820390237>3.0.CO;2-2 Gray, 1976, Clinical testing of the radiosensitizer Ro 03-0582. I. Dose tolerance, serum and tumour concentration, Clin. Radiol., 27, 151, 10.1016/S0009-9260(76)80137-7 1978, 1 Jakobsen, 1985, New prognostic factors in squamous cell carcinoma of cervix uteri, Am. J. Clin. Oncol. (CTT), 8, 39, 10.1097/00000421-198502000-00043 Leibel, 1987, Radiotherapy with or without misonidazole for patients with stage IIIB or stage IVA squamous cell carcinoma of the uterine cervix: preliminary report of a Radiation Therapy Oncology Group randomized trial, Int. J. Radiat. Oncol. Biol. Phys., 13, 541, 10.1016/0360-3016(87)90069-1 1984, Medical Research Council trial of misonidazole in carcinoma of the uterine cervix. A Report from the MRC Working Party on misonidazole for cancer of the cervix, Br. J. Radiol., 57, 491, 10.1259/0007-1285-57-678-491 Overgaard, 1989, Misonidazole combined with radiotherapy in the treatment of carcinoma of the uterine cervix, Int. J. Radiat. Oncol. Biol. Phys., 16, 1069, 10.1016/0360-3016(89)90918-8 Sealy, 1979, Vol. 6, 223 Spiegelhalter, 1993, Applying Bayesian thinking in drug development and clinical trials, Statis. Med., 12, 10.1002/sim.4780121516 1988 Stehman, 1988, A randomized trial of hydroxyurea versus misonidazole adjunct to radiation therapy in carcinoma of the cervix. A preliminary report of a Gynecologic Oncology Group study, Am. J. Obstet. Gynecol., 159, 87, 10.1016/0002-9378(88)90499-1 Ward, 1979, A clinical appraisal of hyperbaric oxygen in cervix cancer, Br. J. Radiol., 51, 150 Watson, 1978, Hyperbaric oxygen and radiotherapy. A Medical Research Council trial in carcinoma of the cervix, Br. J. Radiol., 51, 879, 10.1259/0007-1285-51-611-879 WHO, 1979