A study of the impact of polymer–surfactant in drug nanoparticle coated pharmatose composites on dissolution performance

Kesisoglou, 2007, Nanosizing—oral formulation development and biopharmaceutical evaluation, Adv. Drug Deliv. Rev., 59, 631, 10.1016/j.addr.2007.05.003 Singh, 2011, Investigation of preparation parameters of nanosuspension by top-down media milling to improve the dissolution of poorly water-soluble glyburide, Eur. J. Pharm. Biopharm., 78, 441, 10.1016/j.ejpb.2011.03.014 Tanaka, 2012, Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption, Drug Dev. Ind. Pharm., 38, 1015, 10.3109/03639045.2011.637051 Noyes, 1897, The rate of solution of solid substances in their own solutions, J. Am. Chem. Soc., 19, 930, 10.1021/ja02086a003 Müller, 2011, State of the art of nanocrystals – special features, production, nanotoxicology aspects and intracellular delivery, Eur. J. Pharm. Biopharm., 78, 1, 10.1016/j.ejpb.2011.01.007 Sun, 2012, Nanocrystals for the parenteral delivery of poorly water-soluble drugs, Curr. Opin. Solid State Mater. Sci., 16, 295, 10.1016/j.cossms.2012.10.004 Merisko-Liversidge, 2011, Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology, Adv. Drug Deliv. Rev., 63, 427, 10.1016/j.addr.2010.12.007 Keck, 2006, Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation, Eur. J. Pharm. Biopharm., 62, 3, 10.1016/j.ejpb.2005.05.009 Basa, 2008, Production and in vitro characterization of solid dosage form incorporating drug nanoparticles, Drug Dev. Ind. Pharm., 34, 1209, 10.1080/03639040802005024 Van Eerdenbrugh, 2008, Drying of crystalline drug nanosuspensions—the importance of surface hydrophobicity on dissolution behavior upon redispersion, Eur. J. Pharm. Sci., 35, 127, 10.1016/j.ejps.2008.06.009 Bhakay, 2014, Redispersible fast dissolving nanocomposite microparticles of poorly water-soluble drugs, Int. J. Pharm., 461, 367, 10.1016/j.ijpharm.2013.11.059 Lee, 2003, Drug nano-and microparticles processed into solid dosage forms: physical properties, J. Pharm. Sci., 92, 2057, 10.1002/jps.10471 Azad, 2015, Spray drying of drug-swellable dispersant suspensions for preparation of fast-dissolving, high drug-loaded, surfactant-free nanocomposites, Drug Dev. Ind. Pharm., 41, 1617, 10.3109/03639045.2014.976574 Cheow, 2011, Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: effect of freeze-drying adjuvants, Int. J. Pharm., 404, 289, 10.1016/j.ijpharm.2010.11.021 Wang, 2012, A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid–polymer hybrid nanoparticles, Int. J. Pharm., 424, 98, 10.1016/j.ijpharm.2011.12.045 Layre, 2006, Freeze-drying of composite core-shell nanoparticles, Drug Dev. Ind. Pharm., 32, 839, 10.1080/03639040600685134 de Waard, 2008, A novel bottom–up process to produce drug nanocrystals: controlled crystallization during freeze-drying, J. Control. Release, 128, 179, 10.1016/j.jconrel.2008.03.002 Choi, 2008, Effect of polymer molecular weight on nanocomminution of poorly soluble drug, Drug Delivery, 15, 347, 10.1080/10717540802039113 Kim, 2010, Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions, Int. J. Pharm., 397, 218, 10.1016/j.ijpharm.2010.07.010 Bhakay, 2014, Enhanced recovery and dissolution of griseofulvin nanoparticles from surfactant-free nanocomposite microparticles incorporating wet-milled swellable dispersants, Drug Dev. Ind. Pharm., 40, 1509, 10.3109/03639045.2013.831442 Bhakay, 2013, Recovery of BCS Class II drugs during aqueous redispersion of core–shell type nanocomposite particles produced via fluidized bed coating, Powder Technol., 236, 221, 10.1016/j.powtec.2011.12.066 Bilgili, 2012, A combined microhydrodynamics–polymer adsorption analysis for elucidation of the roles of stabilizers in wet stirred media milling, Int. J. Pharm., 439, 193, 10.1016/j.ijpharm.2012.09.040 Bhakay, 2011, Novel aspects of wet milling for the production of microsuspensions and nanosuspensions of poorly water-soluble drugs, Drug Dev. Ind. Pharm., 37, 963, 10.3109/03639045.2010.551775 Chaubal, 2008, Conversion of nanosuspensions into dry powders by spray drying: a case study, Pharm. Res., 25, 2302, 10.1007/s11095-008-9625-0 Ploehn, 1990, Interactions between colloidal particles and soluble polymers, Adv. Chem. Eng., 15, 137, 10.1016/S0065-2377(08)60194-5 Adamson, 1997 Rowe, 1986, The effect of the molecular weight of ethyl cellulose on the drug release properties of mixed films of ethyl cellulose and hydroxypropylmethylcellulose, Int. J. Pharm., 29, 37, 10.1016/0378-5173(86)90197-3 Mittal, 2007, Estradiol loaded PLGA nanoparticles for oral administration: effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo, J. Control. Release, 119, 77, 10.1016/j.jconrel.2007.01.016 Sepassi, 2007, Effect of polymer molecular weight on the production of drug nanoparticles, J. Pharm. Sci., 96, 2655, 10.1002/jps.20979 Kalyanasundaram, 1977, Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems, J. Am. Chem. Soc., 99, 2039, 10.1021/ja00449a004 Afolabi, 2014, Impact of process parameters on the breakage kinetics of poorly water-soluble drugs during wet stirred media milling: a microhydrodynamic view, Eur. J. Pharm. Sci., 51, 75, 10.1016/j.ejps.2013.09.002 Bilgili, 2016, Is the combination of cellulosic polymers and anionic surfactants a good strategy for ensuring physical stability of BCS Class II drug nanosuspensions?, Pharm. Dev. Technol., 21, 499 Knieke, 2013, A study of the physical stability of wet media-milled fenofibrate suspensions using dynamic equilibrium curves, Chem. Eng. Res. Des., 91, 1245, 10.1016/j.cherd.2013.02.008 Rao, 1997, A mechanistic study of griseofulvin dissolution into surfactant solutions under laminar flow conditions, J. Pharm. Sci., 86, 1132, 10.1021/js9604974 Ain-Ai, 2008, Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound, Int. J. Pharm., 351, 282, 10.1016/j.ijpharm.2007.09.029 Li, 2015, Sub-100nm drug particle suspensions prepared via wet milling with low bead contamination through novel process intensification, Chem. Eng. Sci., 130, 207, 10.1016/j.ces.2015.03.020 Bilgili, 2011, Experimental study of fluidized bed co-granulation of two active pharmaceutical ingredients: an industrial scale-up perspective, Part. Sci. Technol., 29, 285, 10.1080/02726351.2010.516803 Rasenack, 2003, Microcrystals for dissolution rate enhancement of poorly water-soluble drugs, Int. J. Pharm., 254, 137, 10.1016/S0378-5173(03)00005-X Dalvi, 2010, Analysis of nucleation kinetics of poorly water-soluble drugs in presence of ultrasound and hydroxypropyl methyl cellulose during antisolvent precipitation, Int. J. Pharm., 387, 172, 10.1016/j.ijpharm.2009.12.026 de Villiers, 1996, Influence of agglomeration of cohesive particles on the dissolution behaviour of furosemide powder, Int. J. Pharm., 136, 175, 10.1016/0378-5173(95)04380-2 Azad, 2015, Enhanced physical stabilization of fenofibrate nanosuspensions via wet co-milling with a superdisintegrant and an adsorbing polymer, Eur. J. Pharm. Biopharm., 94, 372, 10.1016/j.ejpb.2015.05.028 Moore, 1996, Mathematical comparison of dissolution profiles, Pharm. Technol., 20, 64