A stochastic model for PSA levels: behavior of solutions and population statistics

Journal of Mathematical Biology - Tập 53 - Trang 437-463 - 2006
Pavel Bělík1, P. W. A. Dayananda1, John T. Kemper1, Mikhail M. Shvartsman1
1Department of Mathematics, University of St. Thomas, St. Paul, USA

Tóm tắt

This paper investigates the partial differential equation for the evolving distribution of prostate-specific antigen (PSA) levels following radiotherapy. We also present results on the behavior of moments for the evolving distribution of PSA levels and estimate the probability of long-term treatment success and failure related to values of treatment and disease parameters. Results apply to a much wider range of parameter values than was considered in earlier studies, including parameter combinations that are patient specific.

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