A specific peptide with immunomodulatory activity from Pseudostellaria heterophylla and the action mechanism

Beutler, 2004, Innate immunity: An overview, Molecular Immunology, 40, 845, 10.1016/j.molimm.2003.10.005 Chalamaiah, 2018, Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review (Review), Food Chemistry, 245, 205, 10.1016/j.foodchem.2017.10.087 Dai, 2014, Immunomodulatory activity in vitro and in vivo of verbascose from mung beans (Phaseolus aureus), Journal of Agricultural and Food Chemistry, 62, 10727, 10.1021/jf503510h Ehlers, 2000, CR3: A general purpose adhesion-recognition receptor essential for innate immunity, Microbes and Infection, 2, 289, 10.1016/S1286-4579(00)00299-9 Ferwerda, 2008, Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages, Cellular Microbiology, 10, 2058, 10.1111/j.1462-5822.2008.01188.x Han, 2018, Immunomodulatory activity of Docosahexenoic Acid on RAW264.7 cells activation through GPR120-mediated signaling pathway, Journal of Agricultural and Food Chemistry, 66, 926, 10.1021/acs.jafc.7b05894 Hartley, 2008, Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line, Retrovirology, 5, 1, 10.1186/1742-4690-5-1 Hou, 2012, Purification and identification of immunomodulating peptides from enzymatic hydrolysates of Alaska pollock frame, Food Chemistry, 134, 821, 10.1016/j.foodchem.2012.02.186 Hu, 2013, Hypoglycemic effect of polysaccharides with different molecular weight of Pseudostellaria heterophylla, BMC Complementary and Alternative Medicine, 13, 267, 10.1186/1472-6882-13-267 Kawai, 2010, The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors, Nature Immunology, 11, 373, 10.1038/ni.1863 Kiewiet, 2017, Toll-like receptor mediated activation is possibly involved in immunoregulating properties of cow's milk hydrolysates, PLoS ONE, 12, 10.1371/journal.pone.0178191 Kohchi, 2009, ROS and innate immunity, Anticancer Research, 29, 817 Kong, 2008, Enzymatic preparation of immunomodulating hydrolysates from soy proteins, Bioresource Technology, 99, 8873, 10.1016/j.biortech.2008.04.056 Kundu, 2006, Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-κB and AP-1 as prime targets, Biochemical Pharmacology, 72, 1506, 10.1016/j.bcp.2006.08.005 Lai, 2018, Dicalcium Silicate induced proinflammatory responses through TLR2-mediated NF-κB and JNK pathways in the murine RAW 264.7 macrophage cell line, Mediators of Inflammation, 2018, 8167932, 10.1155/2018/8167932 Li, 2017, Mannose receptor mediates the immune response to Ganoderma atrum polysaccharides in macrophages, Journal of Agricultural and Food Chemistry, 65, 348, 10.1021/acs.jafc.6b04888 Liu, 2015, iTRAQ-based quantitative proteomic analysis of Pseudomonas aeruginosa SJTD-1: A global response to n-octadecane induced stress, Journal of Proteomics, 123, 14, 10.1016/j.jprot.2015.03.034 Lozano-Ojalvo, 2016, Hydrolysates of egg white proteins modulate T- and B-cell responses in mitogen-stimulated murine cells, Food & Function, 7, 1048, 10.1039/C5FO00614G Medzhitov, 2000, The Toll receptor family and microbial recognition, Trends in Microbiology, 8, 452, 10.1016/S0966-842X(00)01845-X Santiago-Lopez, 2016, Food-derived immunomodulatory peptides, Journal of the Science of Food and Agriculture, 96, 3631, 10.1002/jsfa.7697 Sheu, 2009, Purification, cloning, and functional characterization of a novel immunomodulatory protein from Antrodia camphorata (bitter mushroom) that exhibits TLR2-dependent NF-kappaB activation and M1 polarization within murine macrophages, Journal of Agricultural and Food Chemistry, 57, 4130, 10.1021/jf900469a Tu, 2019, Anti-inflammatory effects of Glycine tabacina extract in LPS-stimulated macrophages and collagen-induced arthritis mice, Journal of Functional Foods, 62, 10.1016/j.jff.2019.103528 Wong, 1994, The immunostimulating activities of anti-tumor polysaccharides from Pseudostellaria heterophylla, Immunopharmacology, 28, 47, 10.1016/0162-3109(94)90038-8 Wu, 2017, Characterization and immunomodulatory activity of a novel peptide, ECFSTA, from wheat germ globulin, Journal of Agricultural and Food Chemistry, 65, 5561, 10.1021/acs.jafc.7b01360 Xu, 2019, Purification and identification immunomodulatory peptide from rice protein hydrolysates, Food and Agricultural Immunology, 30, 150, 10.1080/09540105.2018.1553938 Yang, 2019, Immunomodulatory effects of Pseudostellaria heterophylla peptide on spleen lymphocytes via a Ca2+/CaN/NFATc1/IFN-γ pathway, Food & Function, 10, 3466, 10.1039/C9FO00577C Yang, 2019, Investigation on activation in RAW264.7 macrophage cells and protection in cyclophosphamide-treated mice of Pseudostellaria heterophylla protein hydrolysate, Food and Chemical Toxicology, 134, 10.1016/j.fct.2019.110816 Yang, 2018, A β-glucan from Durvillaea Antarctica has immunomodulatory effects on RAW264.7 macrophages via toll-like receptor 4, Carbohydrate Polymers, 191, 255, 10.1016/j.carbpol.2018.03.019 Zhao, 2014, A specific peptide with calcium chelating capacity isolated from whey protein hydrolysate, Journal of Functional Foods, 10, 46, 10.1016/j.jff.2014.05.013