A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis

Redox Biology - Tập 32 - Trang 101485 - 2020
Yanwen Chen1,2, John W. Evankovich1,3, Travis B. Lear1,3,4, Ferhan Tuncer1, Jason R. Kennerdell1, Daniel P. Camarco1, Morgan S. Shishido1, Yuan Liu1,5,6, Bill B. Chen1,3,6
1Aging Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
2Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
3Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA 15213, USA
4Department of Environmental and Occupational Health, School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA
5McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA
6Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA

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