A simple one-step electrochemical deposition of bioinspired nanocomposite for the non-enzymatic detection of dopamine

Journal of Analytical Science and Technology - 2021
Vijayaraj Kathiresan1, Dinakaran Thirumalai2, Thenmozhi Rajarathinam2, Miri Yeom2, Jaewon Lee3, Suhkmann Kim4, Jung‐Sik Yoon5, Seung‐Cheol Chang2
1Graduate Department of Chemical Materials, Pusan National University, Busan, 46241, Republic of Korea
2Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan, 46241, Republic of Korea
3College of Pharmacy, Pusan National University, Busan, 46241, Republic of Korea
4Department of Chemistry, Pusan National University, Busan 46241, Republic of Korea
5Busan Center, Korea Basic Science Institute, Busan, 46241, Republic of Korea

Tóm tắt

AbstractA simple and cost-effective electrochemical synthesis of carbon-based nanomaterials for electrochemical biosensor is of great challenge these days. Our study describes a single-step electrochemical deposition strategy to prepare a nanocomposite of electrochemically reduced graphene oxide (ErGO), multi-walled carbon nanotubes (MWCNTs), and polypyrrole (PPy) in an aqueous solution of pH 7.0 for dopamine (DA) detection. The ErGO/MWCNTs/PPy nanocomposites show enhanced electrochemical performance due to the strong π–π* stacking interactions among ErGO, MWCNTs, and PPy. The efficient interaction of the nanocomposites is confirmed by evaluating its physical and electrochemical characteristics using field-emission scanning electron microscopy, Raman spectroscopy, electrochemical impedance spectroscopy, cyclic voltammetry, and amperometry. The deposited nanocomposites are highly stable on the substrates and possess high surface areas, which is vital to improve the sensitivity and selectivity for DA detection. The controlled deposition of the ErGO/MWCNTs/PPy nanocomposites can provide enhanced electrochemical detection of DA. The sensor demonstrates a short time response within 2 s and is a highly sensitive approach for DA detection with a dynamic linear range of 25–1000 nM (R2 = 0.999). The detection limit is estimated to be 2.3 nM, and the sensor sensitivity is calculated to be 8.96 μA μM−1 cm−2, with no distinct responses observed for other biological molecules.

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