A simple and effective approach for the treatment of diabetic foot ulcers with different Wagner grades

International Wound Journal - Tập 7 Số 3 - Trang 153-158 - 2010
Basavraj Nagoba1, Rajan C Gandhi2, Bharat Wadher3, Arunkumar Rao4, Amol Hartalkar5, Sohan P Selkar6
1Department of Microbiology, MIMSR Medical College and YCR Hospital, Latur, India.
2RC Gandhi, MS, Department of Surgery, MIMSR Medical College and YCR Hospital, Latur, India
3BJ Wadher, PhD, Medical Microbiology Research Laboratory, PG Department of Microbiology, RTM Nagpur University, Nagpur, India
4AK Rao, MS, Department of Orthopedics, MIMSR Medical College and YCR Hospital, Latur, India
5AR Hartalkar, MD, Department of Medicine, MIMSR Medical College and YCR Hospital, Latur, India
6SP Selkar, MP Th, Department of Physiotherapy, MIMSR Medical College, Latur, India

Tóm tắt

Diabetic foot infections are the major cause of morbidity. Infection is the common sequel of diabetic foot ulceration that leads to delayed wound healing. These infections are difficult to control. If not addressed well in time, they may lead to amputation of foot. An attempt has been made to develop simple and effective treatment modality by using citric acid as a sole antimicrobial agent to control diabetic foot infections not responding to conventional treatment. Hundred and fifteen cases of diabetic foot ulcers of different Wagner grades infected with a variety of bacteria were investigated for culture and susceptibility, and susceptibility to citric acid. Citric acid gel was applied to ulcer to determine its efficacy in the management of diabetic foot ulcers with different Wagner grades. Citric acid gel was found effective in the control of foot infections; especially in Wagner grades I and II, the success rate was found to be more than 94%. In Wagner grade III also, it was found effective in complete healing of ulcers without deep osteomyelitis. Citric acid treatment is effective in the control of diabetic foot infections and in successful management of diabetic foot ulcers with Wagner grades I and II, and even with Wagner grade III, without deep osteomyelitis.

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Tài liệu tham khảo

10.1001/jama.293.2.217

Barbul A., 2005, Schwartz's Principles of Surgery, 223

Branemark P, 1966, Local tissue effects of disinfectants., Acta Chir Scand, 357, 166

10.1016/S1062-0303(99)90004-3

Pathare NA., 1998, Infections and diabetes mellitus, J Diabetic Asso Ind, 38, 4

10.1016/0022-4804(74)90046-8

10.1001/archsurg.1986.01400020077009

10.1016/S0305-4179(98)00052-7

10.1016/S0195-6701(98)90095-0

10.1016/j.jhin.2008.03.014

10.1046/j.1365-2133.2002.04634.x

10.1099/jmm.0.47647-0

Collee JG, 1989, Mackie & McCartney Practical Medical Microbiology

10.1093/ajcp/45.4_ts.493

Baron EJ, 1990, Diagnostic Microbiology, 168

10.1007/BF00400697

10.1002/dme.1996.13.s1.12

10.3109/17453679508995520

10.2337/diacare.13.5.513

Budhavari S., 1989, The Merck Index

Thông tin
Thông tin xuất bản

International Wound Journal

Tập 7 Số 3

153-158

Thông tin tác giả