A short-term (accelerated release) approach to evaluate peptide release from PLGA depot formulations

AAPS PharmSci - Tập 1 Số 3 - Trang 1-6 - 1999
Mohammed Shameem1, Heeyong Lee1, Patrick P. DeLuca1
1University of Kentucky College of Pharmacy, Rose Street, Room 327G, 40536-0082, Lexington, KY

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Tài liệu tham khảo

Holden C. Drugs and biotechnology. Science. 1994;248:964.

Okada H, Heya T, Ogawa Y, Shimamoto T. One month release injectable microcapsules of a lutenizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometrosis in rats. J Pharm Exp Ther. 1988;244:744–750.

Walker KJ, Turkes AO, Turkes A, Zwink R, Beacock C, Buck AC, Peeling WB, Griffiths K. Treatment of patients with advanced cancer of the prostate using a slow-release (depot) formulation of the LHRH agonist ICI 118630 (Zoladex). J Endocrinol 1984;103:R1-R4.

Eldrige JH, Staas JK, Meulbroek JA, Tice TR, Gilley RM. Biodegradable and biocompatible poly(dl-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin neutralizing antibodies. Infect Immun. 1991;59:2978–2986.

Bergsma JE, Rozema FR, Bos RR, Boering G, de Bruijn WC, Pennings AJ. In vivo degradation and biocompatability study of in vitro pre-degraded as-polymerized polylactide particles. Biomaterials. 1996;16:267–274.

Aso Y, Yoshiyoka S, Wan Po L, Terao T. Effect of temperature on mechanisms of drug release and matrix degradation of poly (D,L-lactide) microspheres. J Control Release. 1994;31:33–39.

Kaniwa N, Shameem M, Katori N, Aoyagi N, Kojima S. The suitable temperature for the evaluation of controlled release products in vitro. Pharmazie. 1995;50:53–55.

Cha Y, Pitt CG. The acceleration of degradation-controlled drug delivery from polyester microspheres. J Control Release. 1989;8:259–265.

DeLuca PP, Mehta RC, Hausberger AG, Thanoo BC. Biodegradable polyesters for drug and polypeptide delivery In: El-Nokaly MA, Piatt DM, Charpentier BA, eds. Polymer Delivery Systems, Properties and Applications. ACS Symposium Series 520. Washington, DC: American Chemical Society, 1993:53–79.

Shameem M, Lee H, Burton K, Thanoo BC, DeLuca, PP. Effect of-irradiation on peptide-containing hydrophilic poly (d,l-lactide-coglycolide) microspheres. J. Pharm Sci. Tech. (1999). In press.

Mehta RC, Thanoo BC, DeLuca PP. Peptide containing microspheres from low molecular weight and hydrophilic poly(d,l-lactide-co-glycolide). J Control Release. 1996;41:249–257.

Okada H, Doken Y, Ogawa Y, Toguchi H. Preparation of three-month depot injectable microspheres of leuprorelin acetate using biodegradable polymers. Pharm Res. 1994;11:1143–1147.

Park TG, Lu W, Crotts G. Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulate poly (d,l-lactide-co-glycolide) microspheres. J Control Release. 1995;33:211–222.

Mader K, Gallez B, Liu KJ, Swartz HM. Non-invasive in vivo characterization of release processes in biodegradable polymers by low-frequency electron paramagnetic resonance spectroscopy. Biomaterials. 1996;17:457–461.