A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice

Life Sciences - Tập 138 - Trang 72-77 - 2015
Richard D. Ronca1, Alyssa M. Myers2, Doina Ganea3, Ronald F. Tuma1, Ellen A. Walker2, Sara Jane Ward1
1Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA 19140, USA
2Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19140, USA
3Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA

Tài liệu tham khảo

Atwood, 2010, CB2: a cannabinoid receptor with an identity crisis, Br. J. Pharmacol., 160, 467, 10.1111/j.1476-5381.2010.00729.x Bingham, 2012, Watermaze performance after middle cerebral artery occlusion in the rat: the role of sensory motor versus memory impairments, J. Cereb. Blood Flow Metab., 32, 989, 10.1038/jcbfm.2012.16 Bisen-Hersh, 2013, Effects of early chemotherapeutic treatment on learning in adolescent mice: implications for cognitive impairment and remediation in childhood cancer survivors, Clin. Cancer Res., 19, 3008, 10.1158/1078-0432.CCR-12-3764 Bouet, 2007, Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse, Exp. Neurol., 203, 555, 10.1016/j.expneurol.2006.09.006 Diederich, 2014, Cortical photothrombotic infarcts impair the recall of previously acquired memories but spare the formation of new ones, Stroke, 45, 614, 10.1161/STROKEAHA.113.001907 Lakhan, 2009, Inflammatory mechanisms in ischemic stroke: therapeutic approaches, J. Transl. Med., 7 Lee, 2007, Photochemically induced cerebral ischemia in a mouse model, Surg. Neurol., 67, 620, 10.1016/j.surneu.2006.08.077 Marin, 2013, Learning and memory ... and the immune system, Learn. Mem., 20, 601, 10.1101/lm.028357.112 Paolicelli, 2014, Fractalkine regulation of microglial physiology and consequences on the brain and behavior, Front. Cell. Neurosci., 8 Sakai, 1996, Behavioral studies on rats with transient cerebral ischemia induced by occlusion of the middle cerebral artery, Behav. Brain Res., 77, 181, 10.1016/0166-4328(95)00232-4 Vanover, 1998, An automated learning and memory model in mice: pharmacological and behavioral evaluation of an autoshaped response, Behav. Pharmacol., 9, 273 Wake, 2013, Microglia: actively surveying and shaping neuronal circuit structure and function, Trends Neurosci., 36, 209, 10.1016/j.tins.2012.11.007 Walker, 2011, Effects of repeated administration of chemotherapeutic agents tamoxifen, methotrexate, and 5-fluorouracil on the acquisition and retention of a learned response in mice, Psychopharmacology, 217, 539, 10.1007/s00213-011-2310-8 Watson, 1985, Induction of reproducible brain infarction by photochemically initiated thrombosis, Ann. Neurol., 17, 497, 10.1002/ana.410170513 Whyte, 2011, Cognitive impairment in acquired brain injury: a predictor of rehabilitation outcomes and an opportunity for novel interventions, PM R, Jun;3, S45, 10.1016/j.pmrj.2011.05.007 Zhang, 2009, CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury, Microvasc. Res., 10.1016/j.mvr.2009.03.005 Zhang, 2012, Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke, Transl. Stroke. Res., 3, 348, 10.1007/s12975-012-0197-2 Zhang, 2008, Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury, Neuroscience, 152, 753, 10.1016/j.neuroscience.2008.01.022 Zhang, 2007, Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model, J. Cereb. Blood Flow Metab., 10.1038/sj.jcbfm.9600447 Hattori, 2000, Cognitive deficits after focal cerebral ischemia in mice, Stroke, 31, 1939, 10.1161/01.STR.31.8.1939 Cardinal, 2002, Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in rats, Behav. Neurosci., 116, 553, 10.1037/0735-7044.116.4.553