A role for fibroblast growth factor receptor 1 in the pathogenesis of Neisseria meningitidis

Microbial Pathogenesis - Tập 149 - Trang 104534 - 2020
Sheyda Azimi1, Lee M. Wheldon1, Neil J. Oldfield1, Dlawer A.A. Ala’Aldeen1, Karl G. Wooldridge1
1Molecular Bacteriology and Immunology Group, School of Life Sciences, University of Nottingham, UK

Tài liệu tham khảo

Takada, 2016, Meningococcemia in adults: a review of the literature, Intern. Med., 55, 567, 10.2169/internalmedicine.55.3272 Nassif, 1999, Interaction mechanisms of encapsulated meningococci with eucaryotic cells: what does this tell us about the crossing of the blood-brain barrier by Neisseria meningitidis?, Curr. Opin. Microbiol., 2, 71, 10.1016/S1369-5274(99)80012-5 Virji, 2009, Pathogenic neisseriae: surface modulation, pathogenesis and infection control, Nat. Rev. Microbiol., 7, 274, 10.1038/nrmicro2097 Merz, 1999, Type IV pili of pathogenic Neisseriae elicit cortical plaque formation in epithelial cells, Mol. Microbiol., 32, 1316, 10.1046/j.1365-2958.1999.01459.x Eugene, 2002, Microvilli-like structures are associated with the internalization of virulent capsulated Neisseria meningitidis into vascular endothelial cells, J. Cell Sci., 115, 1231, 10.1242/jcs.115.6.1231 Stephens, 1983, Interaction of Neisseria meningitidis with human nasopharyngeal mucosa: attachment and entry into columnar epithelial cells, J. Infect. Dis., 148, 369, 10.1093/infdis/148.3.369 Coureuil, 2014, Invasive meningococcal disease: a disease of the endothelial cells, Trends Mol. Med., 20, 571, 10.1016/j.molmed.2014.08.002 Sokolova, 2004, Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP- and tyrosine kinases in invasion and inflammatory cytokine release, Cell Microbiol., 6, 1153, 10.1111/j.1462-5822.2004.00422.x Hill, 2010, Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease, Clin. Sci. (Lond.), 118, 547, 10.1042/CS20090513 Yazdankhah, 2004, Neisseria meningitidis: an overview of the carriage state, J. Med. Microbiol., 53, 821, 10.1099/jmm.0.45529-0 Simonis, 2014, Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells, PLoS Pathog., 10, 10.1371/journal.ppat.1004160 Bernard, 2014, Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization, Nat. Med., 20, 725, 10.1038/nm.3563 Carbonnelle, 2009, Meningococcal interactions with the host, Vaccine, 27, B78, 10.1016/j.vaccine.2009.04.069 Merz, 2000, Interactions of pathogenic neisseriae with epithelial cell membranes, Annu. Rev. Cell Dev. Biol., 16, 423, 10.1146/annurev.cellbio.16.1.423 Orihuela, 2009, Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models, J. Clin. Invest., 119, 1638, 10.1172/JCI36759 Massari, 2006, Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling, J. Immunol., 176, 2373, 10.4049/jimmunol.176.4.2373 Bartley, 2013, Attachment and invasion of Neisseria meningitidis to host cells is related to surface hydrophobicity, bacterial cell size and capsule, PloS One, 8, 10.1371/journal.pone.0055798 Sa, 2009, Neisseria meningitidis Opc invasin binds to the cytoskeletal protein alpha-actinin, Cell Microbiol., 11, 389, 10.1111/j.1462-5822.2008.01262.x Slanina, 2010, Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases, Infect. Immun., 78, 1905, 10.1128/IAI.01267-09 Slanina, 2012, Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin, PloS One, 7, 10.1371/journal.pone.0039613 Muenzner, 2000, Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells, Infect. Immun., 68, 3601, 10.1128/IAI.68.6.3601-3607.2000 Virji, 1996, Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae, Mol. Microbiol., 22, 941, 10.1046/j.1365-2958.1996.01551.x Kallstrom, 1997, Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria, Mol. Microbiol., 25, 639, 10.1046/j.1365-2958.1997.4841857.x Kirchner, 2005, CD46-independent binding of neisserial type IV pili and the major pilus adhesin, PilC, to human epithelial cells, Infect. Immun., 73, 3072, 10.1128/IAI.73.5.3072-3082.2005 Jen, 2013, Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells, PLoS Pathog., 9, 10.1371/journal.ppat.1003377 Quattroni, 2012, Galectin-3 binds Neisseria meningitidis and increases interaction with phagocytic cells, Cell Microbiol., 14, 1657, 10.1111/j.1462-5822.2012.01838.x Slanina, 2014, Role of epidermal growth factor receptor signaling in the interaction of Neisseria meningitidis with endothelial cells, Infect. Immun., 82, 1243, 10.1128/IAI.01346-13 Hoffmann, 2001, Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis, J. Cell Biol., 155, 133, 10.1083/jcb.200106148 Eswarakumar, 2005, Cellular signaling by fibroblast growth factor receptors, Cytokine Growth Factor Rev., 16, 139, 10.1016/j.cytogfr.2005.01.001 Guillemot, 2011, From cradle to grave: the multiple roles of fibroblast growth factors in neural development, Neuron, 71, 574, 10.1016/j.neuron.2011.08.002 Turner, 2010, Fibroblast growth factor signalling: from development to cancer, Nat. Rev. Canc., 10, 116, 10.1038/nrc2780 Ornitz, 2001, Fibroblast growth factors, Genome Biol., 2, 1, 10.1186/gb-2001-2-3-reviews3005 Ortega, 1998, Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2, Proc. Natl. Acad. Sci. U.S.A., 95, 5672, 10.1073/pnas.95.10.5672 Gerwins, 2000, Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis, Crit. Rev. Oncol. Hematol., 34, 185, 10.1016/S1040-8428(00)00062-7 Presta, 2005, Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis, Cytokine Growth Factor Rev., 16, 159, 10.1016/j.cytogfr.2005.01.004 Groth, 2002, The structure and function of vertebrate fibroblast growth factor receptor 1, Int. J. Dev. Biol., 46, 393 Miki, 1992, Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene, Proc. Natl. Acad. Sci. U.S.A., 89, 246, 10.1073/pnas.89.1.246 Latko, 2019, Cross-talk between fibroblast growth factor receptors and other cell surface proteins, Cells, 8, 10.3390/cells8050455 Reiland, 1993, Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations, J. Cell Sci., 105, 1085, 10.1242/jcs.105.4.1085 Ornitz, 1992, Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells, Mol. Cell Biol., 12, 240 Cavallaro, 2004, Cell adhesion and signalling by cadherins and Ig-CAMs in cancer, Nat. Rev. Canc., 4, 118, 10.1038/nrc1276 Francavilla, 2009, The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking, J. Cell Biol., 187, 1101, 10.1083/jcb.200903030 Zhang, 2006, Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family, J. Biol. Chem., 281, 15694, 10.1074/jbc.M601252200 Lundin, 2003, Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin, Exp. Cell Res., 287, 190, 10.1016/S0014-4827(03)00125-3 Mohammadi, 1996, Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction, Mol. Cell Biol., 16, 977, 10.1128/MCB.16.3.977 Mohammadi, 1992, Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis, Nature, 358, 681, 10.1038/358681a0 Murakami, 2008, The FGF system has a key role in regulating vascular integrity, J. Clin. Invest., 118, 3355, 10.1172/JCI35298 Kanda, 1996, Fibroblast growth factor receptor 1-induced differentiation of endothelial cell line established from tsA58 large T transgenic mice, Cell Growth Differ. : Mol. biol. J. Am. Ass. Canc. Res., 7, 383 Tettelin, 2000, Complete genome sequence of Neisseria meningitidis serogroup B strain MC58, Science, 287, 1809, 10.1126/science.287.5459.1809 Fleischmann, 1995, Whole-genome random sequencing and assembly of Haemophilus influenzae Rd, Science, 269, 496, 10.1126/science.7542800 Fernebro, 2004, Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance, J. Infect. Dis., 189, 328, 10.1086/380564 Oldfield, 2007, T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells, Cell Microbiol., 9, 463, 10.1111/j.1462-5822.2006.00803.x Wheldon, 2011, Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model, Biochem. J., 436, 71, 10.1042/BJ20100884 Burgar, 2002, Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain, J. Biol. Chem., 277, 4018, 10.1074/jbc.M107785200 Mizushima, 1990, pEF-BOS, a powerful mammalian expression vector, Nucleic Acids Res., 18, 5322, 10.1093/nar/18.17.5322 Alqahtani, 2014, Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis, Open Biol., 4, 10.1098/rsob.140053 Virion, 2019, Sialic acid mediated mechanical activation of beta2 adrenergic receptors by bacterial pili, Nat. Commun., 10, 4752, 10.1038/s41467-019-12685-6 Coureuil, 2010, Meningococcus Hijacks a beta2-adrenoceptor/beta-Arrestin pathway to cross brain microvasculature endothelium, Cell, 143, 1149, 10.1016/j.cell.2010.11.035 Coureuil, 2009, Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium, Science, 325, 83, 10.1126/science.1173196 Unkmeir, 2002, Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells, Mol. Microbiol., 46, 933, 10.1046/j.1365-2958.2002.03222.x Schubert-Unkmeir, 2010, Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8, PLoS Pathog., 6, 10.1371/journal.ppat.1000874 van Hinsbergh, 2005, FGFR1 and the bloodline of the vasculature, Arterioscler. Thromb. Vasc. Biol., 25, 883, 10.1161/01.ATV.0000165691.55540.73 Elfenbein, 2012, Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis, Sci. Signal., 5, ra36, 10.1126/scisignal.2002495 Estes, 2006, siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation, Oncol. Rep., 15, 1407 Miller, 2012, Neisseria meningitidis colonization of the brain endothelium and cerebrospinal fluid invasion, Cell Microbiol., 15, 512, 10.1111/cmi.12082 Liu, 1999, Src is required for cell migration and shape changes induced by fibroblast growth factor 1, Oncogene, 18, 6700, 10.1038/sj.onc.1203050 Zhan, 1994, Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin, J. Biol. Chem., 269, 20221, 10.1016/S0021-9258(17)31978-6 Landgren, 1995, Fibroblast growth factor receptor-1 regulation of Src family kinases, Oncogene, 10, 2027 Kim, 2011, Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infection, PLoS Pathog., 7, 10.1371/journal.ppat.1002285 Sahni, 2017, Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium, PLoS One, 12, 10.1371/journal.pone.0183181 Klughammer, 2017, Comparative genome sequencing reveals within-host genetic changes in Neisseria meningitidis during invasive disease, PLoS One, 12, 10.1371/journal.pone.0169892