A role for epigenetic changes in the development of retinal neurodegenerative conditions
Tóm tắt
Từ khóa
Tài liệu tham khảo
Yeo S, et al. Characterization of DNA methylation change in stem cell marker genes during differentiation of human embryonic stem cells. Biochem Biophys Res Commun. 2007;359(3):536–42.
Vaquero A, Loyola A, Reinberg D. The constantly changing face of chromatin. Sci Aging Knowledge Environ. 2003;2003(14):RE4.
Happel N, Doenecke D. Histone H1 and its isoforms: contribution to chromatin structure and function. Gene. 2009;431(1–2):1–12.
Cosgrove MS, Boeke JD, Wolberger C. Regulated nucleosome mobility and the histone code. Nat Struct Mol Biol. 2004;11(11):1037–43.
Allis CD, Jenuwein T, Reinberg D, editors. Epigenetics. New York: Cold Spring Harbor Laboratory Press; 2007.
Taverna SD, et al. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol. 2007;14(11):1025–40.
Oliver SS, Denu JM. Dynamic interplay between histone H3 modifications and protein interpreters: emerging evidence for a “histone language”. ChemBioChem. 2011;12(2):299–307.
Peter IS, Davidson EH. Evolution of gene regulatory networks controlling body plan development. Cell. 2011;144(6):970–85.
Dekker FJ, Haisma HJ. Histone acetyl transferases as emerging drug targets. Drug Discov Today. 2009;14(19–20):942–8.
de Ruijter AJ, et al. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J. 2003;370(Pt 3):737–49.
Grozinger CM, Schreiber SL. Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol. 2002;9(1):3–16.
Saha RN, Pahan K. HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ. 2006;13:539–50.
Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Ann Rev Biochem. 2007;76:75–100.
Agalioti T, Chen G, Thanos D. Deciphering the transcriptional histone acetylation code for a human gene. Cell. 2002;111(3):381–92.
Vogelauer M, et al. Global histone acetylation and deacetylation in yeast. Nature. 2000;408(6811):495–8.
Guo Y, et al. Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model. Invest Ophthalmol Vis Sci. 2011;52(3):1460–73.
Panagis L, et al. Retinal gene expression changes related to IOP exposure and axonal loss in DBA/2J mice. Invest Ophthalmol Vis Sci. 2011;52(11):7807–16.
Pelzel HR, Schlamp CL, Nickells RW. Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis. BMC Neurosci. 2010;11:62.
Rattner A, et al. The genomic response of the retinal pigment epithelium to light damage and retinal detachment. J Neurosci. 2008;28(39):9880–9.
Swiderski RE, et al. Gene expression analysis of photoreceptor cell loss in bbs4-knockout mice reveals an early stress gene response and photoreceptor cell damage. Invest Ophthalmol Vis Sci. 2007;48(7):3329–40.
Van Kirk CA, et al. Age-related alterations in retinal neurovascular and inflammatory transcripts. Mol Vis. 2011;17:1261–74.
Ahmed F, et al. Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure. Invest Ophthalmol Vis Sci. 2004;45:1247–58.
Piri N, et al. Gene expression changes in the retina following optic nerve transection. Mol Vis. 2006;12:1660–73.
Yang Z, et al. Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms. Invest Ophthalmol Vis Sci. 2007;48:5539–48.
Soto I, et al. Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model. J Neurosci. 2008;28(2):548–61.
Schlamp CL, et al. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Mol Vis. 2001;7:192–201.
Janssen KT et al. Nuclear atrophy of retinal ganglion cells precedes the Bax-dependent stage of apoptosis., 2012; in press.
Biermann J, et al. Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells. Invest Ophthalmol Vis Sci. 2010;51(1):526–34.
Pelzel HR et al. Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity. submitted, 2012.
Crosson CE, et al. Inhibition of histone deacetylase protects the retina from ischemic injury. Invest Ophthalmol Vis Sci. 2010;51(7):3639–45.
Miao F, et al. In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J Biol Chem. 2004;279(17):18091–7.
Zhong Q, Kowluru RA. Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenon. J Cell Biochem. 2010;110(6):1306–13.
Suuronen T, et al. Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. Biochem Biophys Res Commun. 2007;357(2):397–401.
Kuo MH, et al. Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription. Mol Cell. 2000;6(6):1309–20.
Suka N, et al. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol Cell. 2001;8(2):473–9.
Palhan VB, et al. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proc Natl Acad Sci U S A. 2005;102(24):8472–7.
Peng CH, et al. Delivery of Oct4 and SirT1 with cationic polyurethanes-short branch PEI to aged retinal pigment epithelium. Biomaterials. 2011;32(34):9077–88.
Wu Z, et al. Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3. J Biol Chem. 2007;282(31):22414–25.
Bardai FH, D’Mello SR. Selective toxicity by HDAC3 in neurons: regulation by Akt and GSK3beta. J Neurosci. 2011;31(5):1746–51.
Sandi C, et al. Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model. Neurobiol Dis. 2011;42(3):496–505.
Rai M, et al. Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich’s ataxia patients and in a mouse model. PLoS One. 2010;5(1):e8825.
Zhang Z, et al. Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia–reperfusion injury. Neurosci Lett. 2011;504(2):88–92.
Biermann J, et al. Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells. Mol Vis. 2011;17:395–403.
Shahid H et al. Age-related macular degeneration: the importance of family history as a risk factor. Br J Ophthalmol, 2011.
Zanke B, et al. A genetic approach to stratification of risk for age-related macular degeneration. Can J Ophthalmol. 2010;45(1):22–7.
Fraga MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A. 2005;102(30):10604–9.
Poulsen P, et al. The epigenetic basis of twin discordance in age-related diseases. Pediatr Res. 2007;61(5 Pt 2):38R–42.
Bollati V, et al. Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res. 2007;67(3):876–80.
Franco R, et al. Oxidative stress, DNA methylation and carcinogenesis. Cancer Lett. 2008;266(1):6–11.
Liu H, et al. Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B. Oncogene. 2007;26(40):5900–10.
Milagro FI, et al. A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss. FASEB J. 2011;25(4):1378–89.
Rampersaud GC, et al. Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr. 2000;72(4):998–1003.
Clemons TE, et al. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study (AREDS) AREDS report no. 19. Ophthalmology. 2005;112(4):533–9.
Jia L, et al. Risk factors for age-related macular degeneration in elderly Chinese opulation in Shenyang of China. Biomed Environ Sci. 2011;24(5):506–11.
Chiu CJ, Taylor A. Dietary hyperglycemia, glycemic index and metabolic retinal diseases. Prog Retin Eye Res. 2011;30(1):18–53.
Seddon JM, et al. The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences. Arch Ophthalmol. 2005;123(3):321–7.
Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US twin study of age-related macular degeneration. Arch Ophthalmol. 2006;124(7):995–1001.
