A review of toxicity studies of single-walled carbon nanotubes in laboratory animals

Regulatory Toxicology and Pharmacology - Tập 74 - Trang 42-63 - 2016
Makoto Ema1, Masashi Gamo1, Kazumasa Honda1
1Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan

Tài liệu tham khảo

Alexander, 2007, Carbon nanotube structures and compositions: implications for toxicological studies, 7 Bermudez, 2002, Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles, Toxicol. Appl. Pharmacol., 70, 86 Braakhuis, 2014, Physicochemical characteristics of nanomaterials that affect pulmonary inflammation, Part. Fibre Toxicol., 11, 18, 10.1186/1743-8977-11-18 Campagnolo, 2013, Biodistribution and toxicity of pegylated single wall carbon nanotubes in pregnant mice, Part. Fibre Toxicol., 10, 21, 10.1186/1743-8977-10-21 Castranova, 2012, Response to pulmonary exposure to carbon nanotubes, 134 Castranova, 2013, Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers, Accou. Chem. Res., 46, 642, 10.1021/ar300004a Chang, 2012, Epithelial-mesenchymal transition contributes to SWCNT-induced pulmonary fibrosis, Nanotoxicology, 6, 600, 10.3109/17435390.2011.594913 Cherukuri, 2006, Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence, Proc. Natl. Acad. Sci. U. S. A., 103, 18882, 10.1073/pnas.0609265103 Chou, 2008, Single-walled carbon nanotubes can induce pulmonary injury in mouse model, Nano Lett., 8, 437, 10.1021/nl0723634 Costa, 2006, Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure, Toxicol. Sci., 91, 237, 10.1093/toxsci/kfj123 Di, 2013, Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes, Am. J. Respir. Cell Mol. Biol., 49, 759, 10.1165/rcmb.2012-0435OC Djuric, 2001, Effect of varying dietary fat levels on rat growth and oxidative DNA damage, Nutr. Cancer, 39, 214, 10.1207/S15327914nc392_9 Donaldson, 2013, Nanotoxicity: challenging the myth of nano-specific toxicity, Curr. Opin. Biotechnol., 24, 724, 10.1016/j.copbio.2013.05.003 Donaldson, 2006, Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety, Toxicol. Sci., 92, 5, 10.1093/toxsci/kfj130 Donaldson, 2010, Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of lung fibre retention in the parietal pleura, inflammation and mesothelioma, Part. Fibre Toxicol., 7, 5, 10.1186/1743-8977-7-5 Driscoll, 2000, Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations, Toxicol. Sci., 55, 24, 10.1093/toxsci/55.1.24 Elder, 2005, Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology, Toxicol. Sci., 88, 614, 10.1093/toxsci/kfi327 Ema, 2011, Evaluation of dermal and eye irritation and skin sensitization due to carbon nanotubes, Regul. Toxicol. Pharmacol., 61, 276, 10.1016/j.yrtph.2011.08.007 Ema, 2013, Genotoxicity evaluation for single-walled carbon nanotubes in battery on in vitro and in vivo assays, J. Appl. Toxicol., 33, 933, 10.1002/jat.2772 Ema, 2015, Reproductive and developmental toxicity of carbon-based nanomaterials: a literature review, Nanotoxicology ENRHES (Engineered Nanoparticles: Review of Health and Environmental Safety), 2009 Erdely, 2008, Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers, Nano Lett., 9, 36, 10.1021/nl801828z Erdely, 2011, Identification of systemic markers from a pulmonary carbon nanotube exposure, Am. Coll. Occup. Environ. Med., 53, S80, 10.1097/JOM.0b013e31821ad724 Faraj, 2010, Long-term follow-up of lung biodistribution and effect of instilled SWCNTs using multiscale imaging techniques, Nanotechnology, 21, 175103, 10.1088/0957-4484/21/17/175103 Folkmann, 2009, Oxidative damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes, Environ. Health Perspect., 117, 703, 10.1289/ehp.11922 Fonseca, 2015, Characterization of exposure to carbon nanotubes in an industrial setting, Ann. Occup. Hyg., 59, 586 Fujita, 2015, Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression, Nanotoxicology, 9, 290, 10.3109/17435390.2014.921737 Fujita, 2015, Size effects of single-wall carbon nanotubes on in vivo and in vitro pulmonary toxicity, Inhal. Toxicol., 27, 207, 10.3109/08958378.2015.1026620 Ge, 2012, Acute pulmonary and moderate cardiovascular responses of spontaneous hypertensive rats after exposure to single-walled carbon nanotubes, Nanotoxicology, 6, 526, 10.3109/17435390.2011.587905 Hansen, 2012, Redox control of teratogenesis, Reprod. Toxicol., 35, 165, 10.1016/j.reprotox.2012.09.004 Huang, 2014, The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development, Biomaterials, 35, 856, 10.1016/j.biomaterials.2013.10.027 Hubbard, 2000, Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study, Am. J. Respir. Crit. Care Med., 161, 5, 10.1164/ajrccm.161.1.9906062 Jacobsen, 2009, Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE−/− mice, Part. Fibre Toxicol., 6, 2, 10.1186/1743-8977-6-2 Jiménez, 2014, Workplace inhalation exposure to engineered nanomaterials. Detection, measurement, and assessment, 77 Johnston, 2010, A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics, Nanotoxicology, 4, 207, 10.3109/17435390903569639 Joviano-Santos, 2014, Evaluation of cardiovascular toxicity of carbon nanotubes functionalized with sodium hyaluronate in oral regenerative medicine, Braz. J. Med. Biol. Res., 47, 560, 10.1590/1414-431X20143894 Kagan, 2010, Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation, Nat. Nanotechnol., 5, 354, 10.1038/nnano.2010.44 Karsch, 2002, Mechanisms for ovarian cycle disruption by immune/inflammatory stress, Stress, 5, 101, 10.1080/10253890290027868 Kisin, 2011, Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos?, Toxicol. Appl. Pharmacol., 252, 1, 10.1016/j.taap.2011.02.001 Kobayashi, 2011, Pulmonary and systemic responses of highly pure and well-dispersed carbon nanotubes after intratracheal instillation, Inhal. Toxicol., 23, 814, 10.3109/08958378.2011.614968 Kolosnjaj-Tabi, 2010, In vivo behavior of large doses of ultrashort and full-length single-walled carbon nanotubes after oral and intraperitoneal administration to Swiss mice, ACS Nano, 4, 1481, 10.1021/nn901573w Kolosnjaj-Tabi, 2012, Toxicity studies of [60]fullerene and carbon nanotubes: state of the art, vol. 3, 49 Krug, 2014, Nanosafety research–are we on the right tract?, Angew. Chem. Int. Ed., 53, 12304 Lam, 2004, Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation, Toxicol. Sci., 77, 126, 10.1093/toxsci/kfg243 Landsiedel, 2014, Application of short-term inhalation studies to assess the inhalation toxicity of nanoparticles, Part. Fibre Toxicol., 11, 16, 10.1186/1743-8977-11-16 Lavranos, 2012, Investigating ROS sources in male infertility: a common end for numerous pathways, Reprod. Toxicol., 34, 298, 10.1016/j.reprotox.2012.06.007 Legramante, 2009, Cardiac autonomic regulation after lung exposure to carbon nanotubes, Hum. Exp. Toxicol., 28, 369, 10.1177/0960327109105150 Li, 2007, Cardiovascular effects of pulmonary exposure to single-walled carbon nanotubes, Environ. Health Perspect., 115, 377, 10.1289/ehp.9688 Li, 2007, Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation, Environ. Toxicol., 22, 415, 10.1002/tox.20270 Lin, 2013, A comparative study of lung toxicity in rats induced by three types of nanomaterials, Nanoscale Res. Lett., 8, 521, 10.1186/1556-276X-8-521 Liu, 2006, Nanoparticles and their biological and environmental applications, J. Biosci. Bioeng., 102, 1, 10.1263/jbb.102.1 Liu, 2007, In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice, Nat. Nanotechnol., 2, 47, 10.1038/nnano.2006.170 Liu, 2008, Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy, Proc. Natl. Acad. Sci., 105, 1410, 10.1073/pnas.0707654105 Loft, 1998, High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2-deoxyguanosine excretion in rats, Free Radic. Res., 29, 595, 10.1080/10715769800300641 Mangum, 2006, Single-walled carbon nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In situ, Part. Fibre Toxicol., 3 Matsumoto, 2012, No toxicological effects on acute and repeated oral gavage doses of single-walled or multi-walled carbon nanotubes in rats, J. Toxicol. Sci., 37, 463, 10.2131/jts.37.463 Maynard, 2004, Exposure to carbon nanotubes material: aerosol release during the handling of unrefined single-walled carbon nanotube material, J. Toxicol. Environ. Health, 67, 87, 10.1080/15287390490253688 McDevitt, 2007, PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice, PLoS One, 2, e907, 10.1371/journal.pone.0000907 McDevitt, 2007, Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes, J. Nucl. Med., 48, 1180, 10.2967/jnumed.106.039131 Mercer, 2008, Alteration of deposition pattern and pulmonary responses as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model, Am. J. Physiol. Lung Cell Mol. Physiol., 294, L87, 10.1152/ajplung.00186.2007 Møller, 2010, Role of oxidative damage in toxicity of particles, Free Rad. Res., 44, 1, 10.3109/10715760903300691 Morimoto, 2012, Pulmonary toxicity of well-dispersed single-wall carbon nanotubes after inhalation, Nanotoxicology, 6, 766, 10.3109/17435390.2011.620719 Morimoto, 2012, Pulmonary toxicity of well-dispersed single-wall carbon nanotubes following intratracheal instillation, J. Nano Res., 18–19, 9, 10.4028/www.scientific.net/JNanoR.18-19.9 Murray, 2009, Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes, Toxicology, 257, 161, 10.1016/j.tox.2008.12.023 Murray, 2012, Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos, Part. Fibre Toxicol., 9, 10, 10.1186/1743-8977-9-10 Mutlu, 2010, Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity, Nano Lett., 10, 1664, 10.1021/nl9042483 Nagai, 2011, Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis, Proc. Natl. Acad. Sci. U. S. A., 108, E1330, 10.1073/pnas.1110013108 Nagai, 2013, Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats, Pathol. Int., 63, 457, 10.1111/pin.12093 Naya, 2011, Evaluation of the genotoxic potential of single-walled carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays, Regul. Toxicol. Pharmacol., 61, 192, 10.1016/j.yrtph.2011.07.008 Naya, 2012, In vivo genotoxicity study of single-wall carbon nanotubes using comet assay following intratracheal instillation in rats, Regul. Toxicol. Pharmacol., 64, 124, 10.1016/j.yrtph.2012.05.020 Nemmar, 2001, Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamsters, Am. J. Crit. Care Med., 164, 1665, 10.1164/ajrccm.164.9.2101036 Nygaard, 2009, Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice, Toxicol. Sci., 109, 113, 10.1093/toxsci/kfp057 Oberdörster, 2002, Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats, J. Toxicol. Environ. Health Part A, 65, 1531, 10.1080/00984100290071658 Oberdörster, 2005, Principles for characterizing the potential human health effects from exposure to nanoparticles: elements of a screening strategy, Part. Fibre Toxicol., 2, 8, 10.1186/1743-8977-2-8 Oberdörster, 2005, Nanotoxicology: an emerging discipline evolution from studies of ultrafine particles, Environ. Health Perspect., 113, 823, 10.1289/ehp.7339 Ogura, 2011, Release potential of single-wall carbon nanotubes produced by super-growth method during manufacturing and handling, J. Nanopart. Res., 13, 1265, 10.1007/s11051-010-0119-8 Ong, 2014, Toxicity of single-walled carbon nanotubes, Arch. Toxicol. Osier, 1997, Intratracheal inhalation vs intratracheal instillation: differences in particle effects, Fundam. Appl. Toxicol., 40, 220, 10.1006/faat.1997.2390 Park, 2011, A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice, Arch. Toxicol., 85, 1121, 10.1007/s00204-011-0655-8 Park, 2014, Toxic response of HIPCO single-walled carbon nanotubes in mice and RAW264.7 macrophage cells, Toxicol. Lett., 229, 167, 10.1016/j.toxlet.2014.06.015 Patlolla, 2011, Biochemical and histopathological evaluation of functionalized single-walled carbon nanotube in Swiss-Webster mice, J. Appl. Toxicol., 31, 75, 10.1002/jat.1579 Penn, 2003, Nanoparticles for bioanalysis, Curr. Opin. Chem. Biol., 7, 609, 10.1016/j.cbpa.2003.08.013 Philbrook, 2011, Investigating the effects of functionalized carbon nanotubes on reproduction and development in Drosophila melanogaster and CD-1 mice, Reprod. Toxicol., 32, 442, 10.1016/j.reprotox.2011.09.002 Pietroiusti, 2011, Low doses of pristine and oxidized single-wall carbon nanotubes affect mammalian embryonic development, ACS Nano, 5, 4624, 10.1021/nn200372g Poland, 2008, Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study, Nat. Nanotechnol., 3, 423, 10.1038/nnano.2008.111 Powers, 2013, Developmental neurotoxicity of engineered nanomaterials: identifying research needs to support human health risk assessment, Toxicol. Sci., 134, 225, 10.1093/toxsci/kft109 Rao, 2003, Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx, J. Toxicol. Environ. Health A, 66, 1441, 10.1080/15287390306417 Saber, 2013, Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk, PLoS One, 8, e69020, 10.1371/journal.pone.0069020 Saxena, 2007, Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-walled carbon nanotubes, Nanotoxicology, 1, 291, 10.1080/17435390701803110 Shvedova, 2005, Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice, Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L698, 10.1152/ajplung.00084.2005 Shvedova, 2007, Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice, Toxicol. Appl. Pharmacol., 221, 339, 10.1016/j.taap.2007.03.018 Shvedova, 2008, Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis, Am. J. Physiol. Lung Cell. Mol. Physiol., 295, L552, 10.1152/ajplung.90287.2008 Shvedova, 2008, Increased accumulation of neutrophil and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes, Toxicol. Appl. Pharmacol., 231, 235, 10.1016/j.taap.2008.04.018 Shvedova, 2008, Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity, Am. J. Res. Cell. Mol. Biol., 38, 579, 10.1165/rcmb.2007-0255OC Shvedova, 2009, Mechanism of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus?, Pharmacol. Ther., 121, 192, 10.1016/j.pharmthera.2008.10.009 Shvedova, 2012, Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficit mice, PLoS One, 7, e30923, 10.1371/journal.pone.0030923 Shvedova, 2012, Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress, Toxicol. Appl. Pharmacol., 261, 121, 10.1016/j.taap.2012.03.023 Shvedova, 2013, Carbon nanotubes enhance metastatic growth of lung carcinoma via up-regulation of myeloid-derived suppressor cells, Small, 9, 1691, 10.1002/smll.201201470 Shvedova, 2014, Long-term effects of carbon containing nanomaterials and asbestos in the lung: one year postexposure comparisons, Am. J. Physiol. Lung Cell. Mol. Physiol., 306, L170, 10.1152/ajplung.00167.2013 Shvedova, 2014, ESR evidence for in vivo formation of free radicals in tissue of mice exposed to single-walled carbon nanotubes, Free Rad. Biol. Med., 73, 154, 10.1016/j.freeradbiomed.2014.05.010 Singh, 2012, Carbon nanotube structure, synthesis, and application, 1 Singh, 2006, Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers, Proc. Natl. Acad. Sci. U. S. A., 103, 3357, 10.1073/pnas.0509009103 Teeguarden, 2011, Comparative proteomics and pulmonary toxicity of instilled single-walled carbon nanotubes, crocidolite asbestos, and ultrafine carbon black in mice, Toxicol. Sci., 120, 123, 10.1093/toxsci/kfq363 Tenzer, 2013, Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology, Nat. Nanotechnol., 8, 772, 10.1038/nnano.2013.181 Tong, 2009, Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice, Toxicol. Appl. Pharmacol., 239, 224, 10.1016/j.taap.2009.05.019 Vesterdal, 2014, Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in ApoE−/− mice, Nanotoxicology, 8, 61, 10.3109/17435390.2012.750385 Wang, 2004, Biodistribution of carbon single-wall carbon nanotubes in mice, J. Nanosci. Nanotechnol., 4, 1019, 10.1166/jnn.2004.146 Wang, 2006, Rapidly functionalized, water-dispersed carbon nanotubes at high concentration, Am. J. Chem. Soc., 95, 95, 10.1021/ja053003q Wang, 2010, Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies, Part. Fibre Toxicol., 7, 31, 10.1186/1743-8977-7-31 Wang, 2015, Use of a pro-fibrogenic mechanism-based predictive toxicological approach for tiered testing and decision analysis of carbonaceous nanomaterials, ACS Nano Warheit, 2004, Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats, Toxicol. Sci., 77, 117, 10.1093/toxsci/kfg228 Wells, 2005, Molecullar and biochemical mechanisms in teratogenesis involving reactive oxygen species, Toxicol. Appl. Pharmacol., 207, S354, 10.1016/j.taap.2005.01.061 Yang, 2007, Biodistribution of pristine single-walled carbon nanotubes in vivo, J. Phys. Chem. C, 111, 17761, 10.1021/jp070712c Yang, 2008, Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice, Toxicol. Lett., 181, 182, 10.1016/j.toxlet.2008.07.020 Zhang, 2013, Functionalized single-walled carbon nanotubes cause reversible acute lung injury and induce fibrosis in mice, J. Mol. Med., 91, 117, 10.1007/s00109-012-0940-x