A rare presentation of clinically intractable hypertension: Pancreatic paraganglioma

ADVANCES IN DIGESTIVE MEDICINE - Tập 3 - Trang 132-134 - 2016
Chao-Ming Tseng1, Jen-Wei Tsai2, Chi-Ming Tai1, Chi-Yang Chang1, TaoQian Tang1, Hsiu-Po Wang3
1Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan
2Department of Pathology, E-DA Hospital, I-Shou University, Kaohsiung, Taiwan
3Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan

Tóm tắt

SummaryParaganglioma is a rare extra‐adrenal pheochromocytoma which originates from chromaffin cells within the ganglia of the sympathetic trunk and of the celiac, renal, suprarenal, and hypogastric plexuses. Pancreatic paragangliomas are rarer still. And even then, paragangliomas are mostly reported to be nonfunctional. We report a case of a 64‐year‐old woman with underlying disease of hypertension who presented with biliary colic. Contrast‐enhanced computer tomography showed an enhancing mass in the uncinate process of the pancreas. Pylorus‐sparing Whipple procedure was performed for complete tumor excision. Hypertensive crisis developed after Whipple, which improved after continuous intravenous nicardipine infusion. Pathology revealed a paraganglioma. A 24‐h catecholamine urine test showed increased norepinephrine and vanillylmandelic acid level. Functional paraganglioma was diagnosed.

Tài liệu tham khảo

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