A prospective study to assess the association between genotype, phenotype and Prakriti in individuals on phenytoin monotherapy

Journal of Ayurveda and Integrative Medicine - Tập 8 - Trang 37-41 - 2017
Saket J. Thaker1, Prajakta P. Gandhe1, Charuta J. Godbole1, Shital R. Bendkhale1, Nitin B. Mali1, Urmila M. Thatte1, Nithya J. Gogtay1
1Dept. of Clinical Pharmacology, 1st Floor New M.S. Building, Seth G.S. Medical College & K.E.M.H., Parel, Mumbai, 400012, India

Tài liệu tham khảo

Johansson, 2011, Genetic polymorphism and toxicology—with emphasis on cytochrome p450, Toxicol Sci, 120, 1, 10.1093/toxsci/kfq374 McNamara, 2011, Pharmacotherapy of the epilepsies, 593 Aynacioglu, 1999, Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin, Br J Clin Pharmacol, 48, 409, 10.1046/j.1365-2125.1999.00012.x Kerb, 2001, The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels, Pharmacogenomics J, 1, 204, 10.1038/sj.tpj.6500025 Zhou, 2008, Clinical pharmacogenetics and potential application in personalized medicine, Curr Drug Metab, 9, 738, 10.2174/138920008786049302 Taur, 2014, Association of polymorphisms of CYP2C9, CYP2C19, and ABCB1, and activity of P-glycoprotein with response to anti-epileptic drugs, J Postgrad Med, 60, 265 Dahanulkar, 1989, Historical survey of the evolution of Ayurveda, 10 Ghodke, 2011, Traditional medicine to modern pharmacogenomics: ayurveda Prakriti type and CYP2C19 gene polymorphism associated with the metabolic variability, Evid Based Complement Altern Med, 2011, 249528, 10.1093/ecam/nep206 Bhalerao, 2012, Prakriti (Ayurvedic concept of constitution) and variations in platelet aggregation, BMC Complement Altern Med, 12, 248, 10.1186/1472-6882-12-248 Govindaraj, 2015, Genome-wide analysis correlates ayurveda Prakriti, Sci Rep, 5, 15786, 10.1038/srep15786 Centre for development of advanced Computing [Home page on internet]. Available from: http://www.cdac.in/index.aspx?id=hi_dss_ayusoft (Last Accessed on 22 June 2016). Rotti, 2014, Determinants of Prakriti, the human constitution types of Indian traditional medicine and its correlation with contemporary science, J Ayurveda Integr Med, 5, 167 Bhalerao, 2016, Prakriti-based research: good reporting practices, J Ayurveda Integr Med, 7, 69, 10.1016/j.jaim.2015.08.002 Sullivan-Klose, 1996, The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism, Pharmacogenetics, 6, 341, 10.1097/00008571-199608000-00007 Rosemary, 2006, Influence of the CYP2C9 AND CYP2C19 polymorphisms on phenytoin hydroxylation in healthy individuals from South India, Indian J Med Res, 123, 665 Neel, 1965, Hardy–Weinberg equilibrium and primitive populations, Am J Hum Genet, 17, 92 Joshi, 1990, Simultaneous estimation of phenytoin, phenobarbitone, and carbamazepine, Indian J Pharmacol, 22, 177 Evans, 2003, Pharmacogenomics—drug disposition, drug targets, and side effects, N. Engl J Med, 348, 538, 10.1056/NEJMra020526 Thakkar, 2012, Association of CYP2C9 polymorphisms with phenytoin toxicity in Indian patients, Neurol India, 60, 577, 10.4103/0028-3886.105189 Kesavan, 2010, Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients, Eur J Clin Pharmacol, 66, 689, 10.1007/s00228-010-0817-2